选择性剪接

mRNA前体选择性剪接的研究进展

Progress in the study of alternative splicing of pre - mRNA

植物前体mRNA的选择性剪接

Pre - mRNA Alternative Splicing in Plants

mRNA选择性剪接的分子机制

Molecular Mechanism of mRNA Alternative Splicing

选择性剪接在Toll样受体4信号转导通路中的作用

The role of alternative splicing in the Toll-like receptor 4 signal transduction

DNA重新甲基化酶3b在成年及新生小鼠部分组织中的选择性剪接表达

Alternative Splicing of de novo Methyltransferase Gene 3b in Adult and Newborn Mice

RNA的选择性剪接是在高等真核生物基因中普遍存在的一种生命现象，它在真核基因表达调控中起着十分重要的作用。

Alternative splicing plays an important role in regulating gene expression . It is widespread in eukaryotic genes .

Bcl-X基因前体mRNA选择性剪接调控研究

The Regulation of the Alternative Splicing of Bcl-X Pre - mRNA

真核生物前体RNA需要经过一系列的转录后加工才能形成成熟的mRNA，这些加工过程包括选择性剪接、RNA编辑以及RNA3'端多聚腺苷酸化等过程。

Before maturing of the eukaryotic mRNA , Pre-mRNA undergoes several processes of post-transcriptional modification , including alternative splicing , editing and polyadenylation .

人IL-4选择性剪接变异体（IL-4δ2）cDNA的克隆和序列测定

Cloning and sequencing of human interleukin 4 alternative splicing variants ( IL 4 δ 2 ) cDNA

真核细胞mRNA前体经过剪接成为成熟的mRNA，而mRNA前体的选择性剪接极大地增加了蛋白质的多样性和基因表达的复杂程度。而内含子内部的组成结构对可变性剪接具有重要的影响。

Eukaryotic pre-mRNAs are spliced to form mature mRNA . The pre-mRNAs alternative splicing greatly increases the diversity of proteins and the complexity of genes expression .

RNA的选择性剪接在真核基因表达调控中起着十分重要的作用。

Research has shown that mRNA affects gene regulation and expression , so splicing , especially alternative splicing of RNA , will affect the control of eukaryotic gene expression .

在生物信息学的飞速发展中，与之相应的各种类型的数据库不断涌现，选择性剪接数据库（AlternativeSplicingDatabase，ASD）便是其中之一。

With the fast development of bioinformatics , all kind of relevant database are keeping appearing , one of which is The Alternative Splicing Database ( ASD ) .

前体mRNA的选择性剪接发生频率很高，它在人类基因组中广泛存在，是增加蛋白质多样性及基因表达复杂程度的主要原因。

Alternative splicing of pre-mRNA , which happens in high frequency and generally exists in genome , is the main reason that increases the diversity of proteins and multiplicity of gene expression .

mRNA前体的选择性剪接具有组织发育阶段性、特异性等特征，在系统发育、分化和癌变过程中发挥着非常重要的作用。

Alternative splicing of pre-mRNA is specific to different stages of development and particular tissues of organism . Moreover , it plays an important role in development , differentiation and cancer of system .

剪切力可通过IGF-I内含子上的元件调控其选择性剪接。

Weightlessness can influence the alternative splicing of IGF-I. FSS can regulated the IGF-I alternative splicing via the intron elements .

NADH选择性剪接的异常可能与宫颈鳞癌的发生发展密切相关。

Abnormal of NADH alternative splicing may be closely related to the occurrence and development of cervical squamous cell carcinoma .

NMD作用的顺式调控元件选择性剪接过程受多种顺式作用元件和反式作用因子相互作用调节。

The alternative splicing is regulated by the interaction between diverse cis-acting elements and trans-acting factors .

MGF是Igf-1基因的选择性剪接变异体，在拉伸刺激的骨骼肌和损伤的神经、肌肉等组织中高表达。

It is an alternative splicing variant of Igf-1 gene which is mainly expressed in stretched skeletal muscle , damaged muscle and neuron .

肾透明细胞癌转移相关的CD99选择性剪接异构体的筛选

Identification of metastasis-associated alternatively spliced variants of CD99 in clear cell renal cell carcinoma tissues

SR蛋白是具有帮助识别正确剪接位点并促进剪接体的成熟的一类重要剪接因子，为组成性剪接所必需，在选择性剪接中更起着不可替代的作用。

SR protein is a kind of splicing factors that help recognition splicing site correctly and promote mature of splicesome , they are essential to constitutive splicing and have pivotal contribution to alternative splicing .

在分子生物学基础研究领域，通过对特定基因的RT-PCR产物的分析，实现了对基因的表达和选择性剪接的直接分析。

Investigation of gene expression and gene alternative splicing by CE was earned out in this study by analyzing the RT-PCR products of the target gene , FMR1 gene , a gene leading to fragile X syndrome .

它们可以结合特定的RNA，参与识别5′及3′剪接位点，与snRNP及其他剪接因子共同完成RNA的组成性和选择性剪接。

They can bind specific RNA , recognize 5 ′ and 3 ′ splice site , help to complete RNA constitutive and alternative splicing with snRNP and other splicing factors .

Cbfα1基因含9个外显子，但它的多个外显子存在选择性剪接，产生多样Cbfα1的异构体，具有不同的转录激活潜能。

The Cbf α 1 gene contains 9 exons , however , the alternative splicing of its exons leads to genesis of multiple Cbf α 1 isoforms with differences in transactivation potentials .

出生后大鼠牙胚组织中nfic基因多种选择性剪接体的克隆研究

Analysis of multiple alternative spliceosome of nfic gene in postnatal rat molar tissues

小麦光周期基因Ppd-B1的选择性剪接分析

Alternative Splicing of Photoperiod Response Gene Ppd-B1 in Wheat

目的探讨人结肠癌组织中是否存在环加氧酶2（COX2）选择性剪接异构体的表达及其可能意义。

Objective To explore the expression of cyclooxygenase 2 ( COX 2 ) alternative splice variant in human colon cancer tissue and its possible significance .

由于选择性剪接M-CSF基因在表达过程中至少可以形成三种异型体，即可溶型M-CSF（s-M-CSF）、膜结合型M-CSF（m-M-CSF）和细胞外基质结合型M-CSF（PG-M-CSF）。

Due to alternative splicing of M-CSF transcripts , M-CSF can exit in at least three isoforms : soluble M-CSF ( s-M-CSF ), membrane-bound M-CSF and extracellular matrix-bound M-CSF ( PG-M-CSF ) .

通过对脊椎动物y-box基因的系统发育分析显示，Y-box基因是在进化过程中通过基因复制或选择性剪接来产生直系同源基因与旁系同源基因，进而使Y-box基因家族成为一个多功能的基因家族。

During the process of vertebrate evolution , the orthologs and paralogs genes were generated by gene duplication or alterative splicing , which may lead to the Y-box gene for a multifunctional protein family .

血管内皮生长因子在人类和鼠成骨细胞中的选择性剪接表达

Alternative splicing expression of VEGF in osteoblasts of human and rat

马慢病毒受体1插入型选择性剪接体的原核表达

Procaryotic Expression of Inserted Alternative Splicing Variants in Equine Lentivirus Receptor-1