血浆蛋白结合率

M1两对映体的总浓度、游离浓度和血浆蛋白结合率无明显区别。

Between the two enantiomers of M 1 , there were no significant differences in total concentrations , free concentrations and plasma protein binding ratio .

AKF-PD的血浆蛋白结合率低，且在SD大鼠与人间不具备种属间差异。

The plasma protein binding of AKF-PD was low , and there was no significant difference between rat plasma and human plasma . 5 .

按平衡透析法测得本品血浆蛋白结合率为51.3±2.2%（（？）±SD，下同）。

The drug-plasma protein binding rate was found to be 51.3 ± 2.2 % (± SD ) using equilibrium dialysis method .

方法：采用平衡透析法结合HPLC，对阿比朵尔的人血浆蛋白结合率进行测定。

METHODS : The equilibrium dialysis combined with HPLC to determine the plasma concentration and plasma protein binding rate of arbidol was carried out .

采用平衡透析法测定了灯盏乙素的血浆蛋白结合率，在血药浓度3.3-37.4μg／ml范围内灯盏乙素血浆蛋白结合率在90.59～93.87%之间，属于高度血浆蛋白结合的药物。

The ratio of scutellarin binding to human plasma was determined by equilibrium dialysis . When the plasma concentration of scutellarin was 3.3-37.4 μ g / ml , the biding ratio was 90.59-93.87 % .

消除半衰期为10h，血浆蛋白结合率为99%，耐受性良好。

The elimination half live is 10 hours , protein bound is 99 % , it has good tolerance .

CMNa平均血浆蛋白结合率为142%。

The average plasma protein binding ratio ( PPBR ) of CMNa was 14 2 % .

可能是由于TL在体内分布广泛，与组织亲和力强，降低了CsA的血浆蛋白结合率所致。

The possible reason is that TL can be widely distributed to the body , it has a strong affinity with the tissue and can decrease CsA 's plasma protein binding rate .

目的应用人工神经网络方法对61种抗生素进行药物分子结构和药物血浆蛋白结合率的定量结构-药物动力学关系的研究（QSPR）。

OBJECTIVE To study and demonstrate the application of neural network to research the quantitative structure-pharmacokinetic relationship ( QSPR ) of 61 kinds of antimicrobial agents .

结论：本研究中ASODN以螯合剂EC与99mTc连接，形成的EC-ASODN其标记率高，放化纯高，比活度符合要求，与血浆蛋白结合率低，复合物稳定。

EC and ASODN were connected by chemical technology . This method is of high labeling yield , of high radiochemical purity , of suitable specific activity and of low plasma protein-combining rate .

三种99mTc-ON的血浆蛋白结合率均小于13%。

The plasma protein binding rate of 99mTc-ON was lower than 13 % .

犤HCPT犦内酯占犤HCPT犦总的10%-20%，血浆蛋白结合率65%-99%，24h尿排泄率24%。

About 10-20 % of the total HCPT circulating in plasma was in the lactone form . The rate of protein bound is 65 % - 99 % Twenty four hour urinary excretion accounted for 24 % of the dose .

方法：选择主要经肾脏排泄的CEZ为模型药，采用高效毛细管电泳法测定其血药浓度，并计算药代动力学参数；采用平衡透析法测定其血浆蛋白结合率。

Methods : The serum concentration of cefazolin and plasma protein binding rate in neijiang pig was detected by high performance capillary electrophoresis .

血浆蛋白结合率为48%。

The rate of binding with plasma protein was 48 % .

目的：测定盐酸去氢骆驼蓬碱的血浆蛋白结合率。

OBJECTIVE To study the plasma protein binding rate of harmine hydrochloride .

超滤法测定药物血浆蛋白结合率的影响因素

Influence factors of determining association ratios of plasma proteins with the ultrafiltration

芒果苷与大鼠体外血浆蛋白结合率的测定方法研究

Assay of in Vitro Plasma Protein Binding Rate of Mangiferin in Rats

氯化两面针碱与大鼠血浆蛋白结合率的测定

Study on rat plasma protein binding rate of nitidine chloride

盐酸去氢骆驼蓬碱血浆蛋白结合率的测定

Determination of plasma protein binding rate of harmine hydrochloride

[3H]洛非西定的血浆蛋白结合率约为38%。

Plasma protein binding rate of lofexidine was ( about ) 38 % .

众所周知，药物血浆蛋白结合率是一个很重要的药代动力学因素。

As well known , drug plasma protein binding is an important pharmacokinetic process .

从分子结构信息预测药物的血浆蛋白结合率

Predicting Drug-plasma Protein Binding from Molecular Structure Information

去铁酮大鼠血浆蛋白结合率的实验研究

Plasma protein binding rate of deferiprone in rats

狗血浆蛋白结合率为（14.45±1.19）%。

The serum protein binding rate in dogs was ( 14.45 ± 1.19 ) % .

最后用三氯醋酸法测定其血浆蛋白结合率。

Finally , the binding rate of plasma protein was determined by trichloroacetic acid precipitation .

蝙蝠葛碱血浆蛋白结合率的研究

Studies of ~ 3h-dauricine plasma protein binding

平均血浆蛋白结合率分别为98.2%，91.8%和97.6%，且均呈现浓度非依赖性。

The average protein binding rates were 98.2 % , 91.8 % and 97.6 % .

微透析法研究磷酸川芎嗪体外血浆蛋白结合率

Determination of Plasma Protein Binding Rate of Tetramethylpyrazine Phosphate in Vitro by Using Microdialysis Method

目的：从电性参数和分子体积预测药物的血浆蛋白结合率。

Objective : To predict the percentage of drug-protein binding from electronic parameters and molecular volume .

用平衡透析法测定普拉西坦的血浆蛋白结合率约为20.1%～22.2%。以上结果表明，普拉西坦吸收快，分布广，消除也快。

The plasma protein combining rate detected by the method of balance dialysis was 20.1 22.2 % .