萘啶酸
- nalidixic acid
![萘啶酸](../cache/1192568.jpg)
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而磺胺甲口恶唑/甲氧苄啶、四环素、萘啶酸等耐药率相对较高,应慎用。
But the resistant rate to trimethoprim / sulfamethoxazole , tetracycline and nalidixic acid were considerably high , they should be carefully used in therapy .
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萘啶酸、诺氟沙星、氧氟沙星、斯巴沙星、环丙沙星对该酶活性50%抑制浓度(1C_(50))分别为10.46、1.35、0.35、0.42和0.12μg/ml。
The 50 % inhibitory concentra-tion ( IC50 ) of nalidixic acid , norfloxacin , ofloxacin , sparfloxacin and ciprofloxacin were 10 . 46 、 1 . 35 、 0.35 、 0.42 、 0.12 μ g / ml respectively .
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金黄色葡萄球菌和大肠埃希菌对萘啶酸和诺氟沙星的耐药升至50%以上,甲型副伤寒沙门菌则高达96%~97%,对氨苄西林、头孢唑林也都有明显升高(P0.01);
Staphylococcus aureus and Escherichia coli resistant to nalidixic acid and norfloxacin were above 50 % , while Salmonella paratyphi A was 96 97 % , whose drug resistance to ampicillin and cefazolin had an obvious rise also ( P0.01 );
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稀土-萘啶酸螯合物的发光特性及萘啶酸与牛血清白蛋白的结合作用
Luminescence Behavior of Lanthanide - Nalidixic Acid Chelates and the Binding of Nalidixic acid to Bovine Serum Albumin
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结果两市痢疾菌株的耐药率除萘啶酸外(P<0.05),其它6种抗生素耐药率均无显著性差异(均P>0.05)。
Results : NO significance of difference between the antibiotic resistance rate of Shigella isolates of two cities but Nalidixic Acid .
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可直接测定尿液中的萘啶酸含量,其回收率为96.6%~102.6%。
This method has been used to determine nalidixic acid in human urine with recoveries of 96.6 % ~ 102.6 % .
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其中镁离子与萘啶酸配合物的荧光较萘啶酸强58倍。
Among them the fluorescence intensity of magnesium - nalidixic acid system was 58 folds more than that of nalidixic acid itself .
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提出了同时测定人血浆中的西诺沙星和萘啶酸的高效液相色谱方法。
A method for the determination of cinoxacin and nalidixic acid in human plasma by reverse-phase high performance liquid chromatography is introduced .
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观察了喹诺酮药物萘啶酸及氟哌酸对人血清白蛋白荧光的猝灭现象。
The fluorescence quenching behavior of human serum albumin by the quinolone antibacterials , nalidixic acid and norfloxacin , has been studied in detail .
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背景:喹诺酮类药物是一大类人工合成的抗菌药,自1962首次研制成功第一个喹诺酮类药物&萘啶酸以来,该类药物发展非常迅速。
Background : Quinolone is a kind of synthetic antibacterial agents . Rapid development has been made since the first quinolone-nalidixic acid was synthesized successfully in 1962 .
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246株分离菌株中,有52株对萘啶酸、环丙沙星、恩诺沙星、沙拉沙星、洛美沙星、左氟沙星表现出轻度的耐性,其余菌株为敏感菌株。
246 isolates , there are 52 pairs showed mild patience of nalidixic acid , ciprofloxacin , enrofloxacin , sarafloxacin , lomefloxacin , levofloxacin , and the remaining strains were sensitive strains .