萘啶酸

而磺胺甲口恶唑/甲氧苄啶、四环素、萘啶酸等耐药率相对较高，应慎用。

But the resistant rate to trimethoprim / sulfamethoxazole , tetracycline and nalidixic acid were considerably high , they should be carefully used in therapy .

萘啶酸、诺氟沙星、氧氟沙星、斯巴沙星、环丙沙星对该酶活性50%抑制浓度（1C＿（50））分别为10.46、1.35、0.35、0.42和0.12μg／ml。

The 50 % inhibitory concentra-tion ( IC50 ) of nalidixic acid , norfloxacin , ofloxacin , sparfloxacin and ciprofloxacin were 10 . 46 、 1 . 35 、 0.35 、 0.42 、 0.12 μ g / ml respectively .

金黄色葡萄球菌和大肠埃希菌对萘啶酸和诺氟沙星的耐药升至50%以上，甲型副伤寒沙门菌则高达96%～97%，对氨苄西林、头孢唑林也都有明显升高（P0.01）；

Staphylococcus aureus and Escherichia coli resistant to nalidixic acid and norfloxacin were above 50 % , while Salmonella paratyphi A was 96 97 % , whose drug resistance to ampicillin and cefazolin had an obvious rise also ( P0.01 );

稀土-萘啶酸螯合物的发光特性及萘啶酸与牛血清白蛋白的结合作用

Luminescence Behavior of Lanthanide - Nalidixic Acid Chelates and the Binding of Nalidixic acid to Bovine Serum Albumin

结果两市痢疾菌株的耐药率除萘啶酸外（P<0.05），其它6种抗生素耐药率均无显著性差异（均P>0.05）。

Results : NO significance of difference between the antibiotic resistance rate of Shigella isolates of two cities but Nalidixic Acid .

可直接测定尿液中的萘啶酸含量，其回收率为96.6%～102.6%。

This method has been used to determine nalidixic acid in human urine with recoveries of 96.6 % ~ 102.6 % .

其中镁离子与萘啶酸配合物的荧光较萘啶酸强58倍。

Among them the fluorescence intensity of magnesium - nalidixic acid system was 58 folds more than that of nalidixic acid itself .

提出了同时测定人血浆中的西诺沙星和萘啶酸的高效液相色谱方法。

A method for the determination of cinoxacin and nalidixic acid in human plasma by reverse-phase high performance liquid chromatography is introduced .

观察了喹诺酮药物萘啶酸及氟哌酸对人血清白蛋白荧光的猝灭现象。

The fluorescence quenching behavior of human serum albumin by the quinolone antibacterials , nalidixic acid and norfloxacin , has been studied in detail .

背景：喹诺酮类药物是一大类人工合成的抗菌药，自1962首次研制成功第一个喹诺酮类药物&萘啶酸以来，该类药物发展非常迅速。

Background : Quinolone is a kind of synthetic antibacterial agents . Rapid development has been made since the first quinolone-nalidixic acid was synthesized successfully in 1962 .

246株分离菌株中，有52株对萘啶酸、环丙沙星、恩诺沙星、沙拉沙星、洛美沙星、左氟沙星表现出轻度的耐性，其余菌株为敏感菌株。

246 isolates , there are 52 pairs showed mild patience of nalidixic acid , ciprofloxacin , enrofloxacin , sarafloxacin , lomefloxacin , levofloxacin , and the remaining strains were sensitive strains .