药物遗传学

炎症性肠病药物遗传学与临床相关性研究现状

Status quo of Pharmacogenetics and Clinical Pertinent Study of Inflammatory Bowel Disease

叶酸相关类抗肿瘤药物遗传学研究进展

Progress in pharmacogenetics of folate-related drug targets in cancer treatment

本文着重综述与铂类药物抵抗有关的DNA修复途径关键因子的SNPs研究，初步探讨药物遗传学在肿瘤的化疗药物选择方面的指导作用。

The SNPs of key genes in DNA repair pathways and their potential effects in chemotherapeutics selections are discussed in this paper .

基于PCR和荧光原位杂交（FISH）技术的分子检测手段，用以帮助临床医生选择恰当的药物遗传学方法治疗，雅培在这方面是先行者。

Abbott is a pioneer in the use of molecular tests based on PCR and fluorescence in situ hybridization ( FISH ) technologies to aid clinicians in the selection of appropriate pharmacogenomic therapies .

氟尿嘧啶治疗胃肠道肿瘤的药物遗传学研究进展

Pharmacogenetics Study of Fluorouracil-based Chemotherapy in Treatment for Gastroenteric Tumor

药物基因组学：将基因组学应用于药物遗传学的学科。

Pharmacogenomics & The application of genomic information or methods to pharmacogenetic problems .

药物遗传学是在分子水平上研究这些差异的科学。

Pharmacogenomics is the science of studying these variatio at the molecular level .

药物遗传学在肿瘤化疗中的应用

Application of pharmaceutical genetics in chemotherapy of tumor

但药物遗传学要改变这种情况。

Pharmacogenetics seeks to change all that .

未来的治疗药物监测模式是传统模式和药物遗传学监测相结合，进一步完善个体给药方案的制定。

The mode of TDM in the future is the combination of traditional methods and pharmacogenetics .

药物遗传学与癌症治疗

Pharmacogenetics and Cancer Therapy

已被广泛熟知的宿主相关因素包括年龄、性别、种族和药物遗传学。

In host related factors , which are generally known as age , gender , race , and pharmacogenetics .

随着人们对人类基因组和人类基因组多样性研究的逐步深入，药物遗传学已发展到一个新的阶段-药物基因组学。

Along with the development of human genome project and human genome diversity research , pharmacogenomics is established from pharmacogenetics recently .

该文主要对药物遗传学与肿瘤药物治疗（包括药物治疗结果与毒副反应）、分子靶向治疗的关系进行综述。

The relationship between pharmacogenetics and drug therapy ( including treatment outcome and toxicity ), and molecular target therapy of cancer are discussed in this review .

药物遗传学是基于人群的遗传变异研究该人群对药物的遗传反应的分别。

Pharmacogenomics is the study of the stratification of the pharmacological response to a drug by a population based on the genetic variation of that population .

这项协议表明我们专注于个体化治疗和开发分子分析手段用以筛选出哪些患者最可能从药物遗传学治疗中受益。

The agreement is indicative of our focus on personalized medicine and developing analytical molecular tools to identify patients most likely to benefit from important pharmacogenomic therapies .

他还说，以上情况是药物遗传学的一个基本的例子，需要更多研究来确定这个领域对发展中国家具有的成本效应和价值。

He explains that this is a basic example of pharmacogenetics , but adds that more research is needed to determine how cost-effective and valuable the field is to developing countries .

目的：了解炎症性肠病药物遗传学的现状，为该类药物在临床的合理应用提供参考。

OBJECTIVE : To investigate status quo of pharmacogenetics of inflammatory bowel disease ( IBD ), in order to provide some references for rational use of such kinds of drugs in the clinic .

药物遗传学的应用包括减少副作用，定制药物，改善临床实验以及挽救一些由于对少数人群会产生严重副作用而被禁用的药物。

Applications of pharmacogenomics include reducing side effects ; customized drugs ; improved clinical trials ; and the rescue of some drugs that have been banned due to severe side effects in a small percentage of the eligible population .