药物排泄

结论：大鼠胆汁、粪和尿中主要以伪人参皂苷GQ原形药物排泄。

Objective : To determine the pseudo-ginsenoside GQ ( PGQ ) in rat bile , feces and urine , and to study on the excretion of pseudo-ginsenoside GQ .

转运体在药物排泄中的作用及在新药研发中的意义

Role of transporters in the drug excretion and its significance in new drug development

小鼠或大鼠（用于胆汁排泄试验）静注盐酸nolarrexed80mg八g的排泄试验显示尿、粪和胆汁中原型药物的排泄分别占给药总量的2.8%、

Mice or rats ( used for bile excretion test ) were administered intravenously with nolatrexed dihydrochloride at 80 mg / kg .

促进药物的排泄可能是改善马钱子性癫痫最为有效的措施，而苯巴比妥可能是轻型马钱子性癫痫的首选药物。

In our study , we also suggest Phenobarbital is the better against epilepsy drug foe non-serious epilepsy caused by Nux vomica .

肝脏、肾脏的药物代谢排泄降低，心功能、肺功能及骨髓的造血功能，也会随年龄增加而受到影响，心功能下降、肺功能减退。

The liver , kidney drug metabolism discharge reduce , the heart , lung function and the bone marrow hematopoietic function , also can increase along with the age and affected , decreased cardiac function , reduced lung function , the bone marrow hematopoietic function is reduced .

结论：奥拉西坦是一吸收快、消除快、主要以原形药物由尿排泄、蛋白结合率低的药物。

The protein binding was found to be low .

肾脏转运蛋白对药物在体内排泄和重吸收过程重要作用。

Renal transporters play an important role in the excretion and reabsorption of drugs and metabolites .

以液液萃取&反相高效液相色谱法研究SD大鼠静脉注射虎杖苷后药物体内分布及排泄情况。

The distribution of PD in rats was studied .