药物吸收

Caco-2细胞模型&药物吸收研究的有效工具

Caco-2 cell model & an effective tool for the research of drug absorption

H5N1重症患者或伴有严重胃肠道症状H5N1患者的药物吸收可能会受到损害。

In severely ill H5N1 patients or in H5N1 patients with severe gastrointestinal symptoms , drug absorption may be impaired .

纳米TiO2在提高肿瘤细胞药物吸收及抗耐药性中的作用

Enhancement Effect of Nano TiO_2 on the Drug Uptake of Tumor Cells

环糊精（CD）及其衍生物作为一类安全有效的鼻腔制剂附加剂，能明显的促进药物吸收，增加药物的生物利用度。

As one of safe and effective excipients in nasal drug formulations , cyclodextrins can enhance the absorption and the bioavailability of the drugs for nasal delivery .

Caco-2模型在肽类药物吸收特性研究中的应用

Application of Caco-2 Model in the Research on Transport Mechanism of Peptide

比较AUC、Cmax等药动学参数来了解药物吸收的情况。

The absorbed situation of drug was comprehended by comparing AUC , Cmax and other pharmacokinetic parameters .

对计算药物吸收速率常数的Wagner-Nelson法的一点改进

An improvement on the Wagner-Nelson method for computing drug absorption rate constant

将瘢痕膏及基质涂在瘢痕部位，并轻揉直到药物吸收，3次/d，连续用药28d。

Scar unguent and ground substance were smeared on the scared sites and rubbed until the absorption of it , three times a day for 28 successive days .

结果表明，灌流速度对药物吸收速率常数（Ka）和表观吸收系数（Papp）有极显著影响（P<0.01）；

The results showed that perfusion flow rate could significantly affect the drug absorption constant ( Ka ) and apparent absorption coefficient ( Papp ) ( P < 0.01 ) .

Caco-2细胞可以用于体外药物吸收研究，因为这种细胞与小肠上皮细胞在形态学和功能上具有相似性，如同样表达细胞色素P450酶和P-糖蛋白。

And Caco-2 cells also can be used to characterize the absorption of oral drugs , because the cells exhibit both morphological and functional similarities to the human small intestinal epithelial cells such as cytochrome p450 enzymes and p-glycoprotein .

他认为葡萄柚汁不是唯一影响药物吸收的果汁，因为橙汁和苹果汁中也含有柚皮素样物质，可能抑制OATP1A2。

He added that grapefruit juice may not be the only type of fruit juice that affects drug absorption , as orange and apple juices also contain naringin-like substances that may inhibit OATP1A2 .

一个分析药物吸收动力学的方法

A method for the analysis of the absorption kinetics of drugs

溶解速率溶解速率决定药物吸收时的可用度。

Dissolution rate determines the availability of the drug for absorption .

生物利用度表示药物吸收进入体循环的分量。

Bioavailability expresses the extent of drug absorption into the systemic circulation .

用于人体药物吸收研究的定点释放药丸系统研制

A site-specific delivery capsule for human drug absorption studies

药物吸收速率常数的一种简便计算法

A simple method for computing drug absorption rate constant

脂质体模拟生物膜研究药物吸收

Studies on Drugs Absorption Using Liposome to Simulate Biomembrane

应用纳米技术增加难溶性药物吸收的研究进展

Advances in research on nanotechnology for enhancing the absorption of poorly water-soluble drugs

口服药物吸收中的生物药剂学性质

Impacts of biopharmaceutical characteristics on oral drug absorption

肠道转运蛋白在药物吸收中的重要作用

Significant role of intestinal transporters in drug absorption

几丁聚糖在促进药物吸收中的应用

Application of Chitosan in Drug Absorption Enhancement

药物吸收和转运的研究模型

The Models of Drug Absorption and Transit

小肠在胃肠道中具有最大的药物吸收表面积。

The small intestine has the largest surface area for drug absorption in the GI tract .

文中对于每法的条文出处、具体操作和药物吸收原理进行了较详尽的探析。

The authors discussed the source of the quotation , operating method , mechanism of drug absorption .

结论：注射前按摩局部皮肤可促进药物吸收，降低皮下出血发生率。

Massaging the local skin pre-injection can accelerate drug absorbing , and lessen the morbility of subcutaneous haemorrhage .

综述了近年来肠道、皮肤、鼻腔、眼、呼吸道、直肠等制剂中的药物吸收促进剂毒性的研究概况。

Effects of absorption promoter on drug permeability in one-way slow release of compound tinidazol from the drug film ;

该材料还具有良好的生物相容性，无毒性和促进药物吸收等特点。

It also has many advantages , such as fine biological compatibility , innocuity , contribution to the pharmaceutical absorption , etc.

临床药代动力学是一门研究临床用药过程中人体内药物吸收、分布、代谢、排泄的动力学过程的学科。

Clinical pharmacokinetics is a subject which studies on absorption , distribution , metabolism and excretion process after drug administration in human body .

他们指出雪碧看起来好像通过让更多药物吸收进入人体的方法控制胃酸。

They showed that Sprite seemed to control stomach acidity in a way likely to allow greater absorption of the drug into the body .

结论本法适用于人体双氢青蒿素血药浓度测定，栓剂与片剂的人体药物吸收程度等效，栓剂吸收速度呈缓释特征。

CONCLUSION : The method can apply to determinating dihydroartemisinin in human serum . Dihydroartemisinin suppository was bioequivalence to the tablet in absorption power , slow-release in absorption speed .