芦荟大黄素

首先，本文通过HPLC条件优化筛选，建立了同时测定大黄药材中没食子酸、番泻苷A、芦荟大黄素、大黄素、大黄酚的HPLC含量测定方法，该方法稳定可靠，重现性良好。

The good results were obtained . Firstly , HPLC method was established for quantitatively simultaneous determining Gallic acid , Sennosides A , Aloe emodin , Emodin and Chrysophanol in Rhubarb . The method is stable and reliable , good reproducibility .

芦荟大黄素在水和非水溶剂中的电化学性质

Electrochemical Properties of Aloe Emodin in Aqueous and Nonaqueous Solvents

芦荟大黄素对球囊动脉血管损伤后体外培养的平滑肌细胞c-myc基因表达的影响

Effect of Aloe-Emodin on c myc Gene Expression of Cultured Vascular Smooth Muscle Cells of Injuried Artery

利用荧光光谱法和圆二色谱法研究了重组内皮抑素与中药有效成分芦荟大黄素的相互作用机制，求得两者在25℃和37℃的结合常数Ka为6.623×104和3.796×104。

The interaction mechanism of recombinant endostatin with aloe-emodin was studied by fluorescence quenching method and circular dichroism spectra .

L-1，芦荟大黄素轻微抑制HK-2细胞增殖，大黄酚作用不明显。

Aloe-emodin had mild inhibitory effects and chrysophanol showed no effects on the proliferation of HK-2 cells .

芦荟大黄素对硬皮病成纤维细胞增殖的影响

Effects of aloe-emodin on the Proliferation of Systemic Scleroderma Skin Fibroblasts

炮制方式对大黄汤中芦荟大黄素含量的影响

Effect of Drug Processing Methods on Concentration of Aole-emodin in Rhubarb Decoction

芦荟大黄素对大鼠实验性急性胰腺炎的作用

Therapeutic effect of Aloe-emodin for experimental acute pancreatitis in rats

芦荟大黄素诱导肿瘤细胞凋亡的研究进展

Apoptosis - inducing effects of Aloe-emodin on tumor cells

芦荟大黄素对瘢痕成纤维细胞增殖的时间-剂量依赖性效应

Effect of aloe-emodin on proliferation of scar fibroblasts in a time-and dose-dependent manner

目的建立芦荟大黄素的差示脉冲伏安测定方法。

OBJECTIVE To establish a novel differential pulse voltammetric method for aloe-emodin determination .

毛细管电泳法测定β-环糊精与芦荟大黄素包合反应平衡常数

Determination of Binding Constant Between β - Cyclodextrin and Aloe-emodin by Capillary Electrophoresis

芦荟大黄素对动脉损伤后血管平滑肌细胞增殖的影响

Effect of Aloe Emodin on Proliferation of Vascular Smooth Muscle Cells after Arterial Injury

芦荟大黄素与血清白蛋白的相互作用

The Interaction of Serum Albumin with Aloe-emodin

芦荟大黄素的差示脉冲伏安法测定

Determination of Aloe-emodin by Differential Pulse Voltammetry

相溶解度法研究芦荟大黄素和环糊精及其衍生物的包结作用

The Study on the Inclusion Action of Aloe Emodin with CDs by Phase Solubility Method

目的：建立血浆及组织匀浆样品中4种大黄蒽醌衍生物芦荟大黄素、大黄酸、大黄素和大黄酚的反相高效液相色谱测定法。

Objective : To establish HPLC method for determination of Rhubarb anthraquinones ( aloe - emodin , rhein , emodin and chrysophanol ) in biological samples .

目的：观察中药大黄活性成分芦荟大黄素对瘢痕成纤维细胞增殖的影响。

AIM : To observe the effect of aloe-emodin , one of the active ingredient of herbal medicine rhubarb , on the proliferation of scar fibroblasts .

方法根据双波长原理，分别在测定波长255376nm，参比波长355475nm处测定芦荟大黄素和芦荟甙含量。

Methods Wavelengths were selected at 255 nm and 355 nm , and the reference wavelengths at 376 nm and 475 nm for Aloe-Emodin and Aloin respectively .

方法：以总蒽醌含量，芦荟大黄素、大黄酸、大黄素、大黄酚和大黄素甲醚的总量为指标，对不同干燥方法进行考察。

METHODS : The vaccum and spray methods were studied by determination of total anthraquinones and the sum of aloe-emodin , rhein , emodin , chrysophanol and physcion .

芦荟大黄素是芦荟中一种蒽醌类化合物，具有强有效的抗肿瘤活性，可应用于医药原料、中间体和抗癌药物的开发当中，在医药领域上有着广阔的应用前景。

Aloe-emodin is an anthraquinone compounds in aloe , with strong anti-tumor activity , could be applied to pharmaceutical raw materials , intermediates and anti-cancer drugs , etc. fields .

大量文献报道大黄中的三种蒽醌类化合物大黄酸、大黄素和芦荟大黄素能够抑制肿瘤细胞增殖、促进肿瘤细胞凋亡、抑制肿瘤血管形成、逆转肿瘤细胞多药耐药等多方面的抗肿瘤活性。

It was reported that the anthraquinone derivatives of rhubarb could inhibit tumor cell proliferation , induce tumor cell apoptosis , block blood vessel formation and even reverse multi-drug resistance .

目的探讨芦荟大黄素对兔髂动脉损伤后内膜增生及血管重塑反应的影响。

Objective To investigate the impact of Aloe emodin on intimal hyperplasia after iliac arteries injury of rabbits and the preventive effect of this agent on restenosis in animal model .

紫外检测波长：191nm。结果桃核承气汤中芦荟大黄素、大黄酸、大黄素、大黄酚、苦杏仁苷的平均加样回收率分别为：99.0%、99.5%、102.4%、103.4%、101.6%；

Results The average recoveries of aloe-emodin , rhein , emodin , chrysophanol and amygdalin were 99.0 % , 99.5 % , 102.4 % , 103.4 % and 101.6 % respectively .

结论：大黄素和芦荟大黄素对大鼠脑缺血损伤均具有保护作用，以低剂量大黄素和高剂量芦荟大黄素抗大鼠脑缺血损伤的作用尤为显著。

Conclusion : Emodin and Aloe-emodin had the obvious protection effect in treating cerebral ischemia , and the low dose group of emodin and the high doses of group emodin had the obvious effect .

结果：（1）不同浓度的芦荟大黄素（12.5-50μM）和隐丹参酮（2.5-10μM）作用于t-HSC/C1-6细胞后明显抑制t-HSC/C1-6细胞生长率，呈剂量和时间依赖性。

Results : ( 1 ) Treatment of t-HSC / Cl-6 cells with these two compounds ( 12.5-50 μ M aloe emodin or 2.5-10 uM cryptotanshinone ) both inhibited t-HSC / Cl-6 cell viability in a dose - and time-dependent manner .

等吸收双波长分光光度法同时测定芦荟中芦荟大黄素和芦荟甙

Determination of Aloe-Emodin and Aloin without Separation by Dual-Wavelength Spectrophotometry

应用双波长标准加入分光光度法同时测定芦荟中芦荟大黄素甙和芦荟大黄素的含量。

Dual-wavelength standard addition spectrophotometry was applied to simultaneous determination of aloin and Aloe-emodin in Aloe Vera .

四工作曲线法同时测定芦荟甙和芦荟大黄素

Simultaneous determination of aloin and aloe-emodin by using four working curves

测定芦荟素和芦荟大黄素的硼砂光度法

Determination of Aloin and Aloe-emodin by Means of Borax-Spectrophotometry