色素减退

发病时和病愈后皮损处常表现为色素减退或色素沉着，治愈后色素改变常需数月甚至数年后才能恢复正常。

It is often represented hypopigmentation and hyperpigmentation in the regions of lesion during eruption and after cure , which may not disappear for months or even years .

3例患者出现暂时性的色素减退。

Transient hypopigmentation occurred in 3 cases .

色素减退处组织病理检查示基底层色素减少，黑素细胞数目亦正常。

The numbers of melanocytes are normal in hyper-pigmented and hypo-pigmented macules .

中西医结合治疗外阴色素减退性疾病55例临床观察

Treatment of 55 Cases of Vulval Hypopigmented Diseases by Combined Chinese and Western Medicine

结果：临床症状消失，慢性溃疡愈合，踝关节区域水肿消失，色素减退。

Results : No clinical symptoms and ankle oedema exist , chronic venous ulcer cured . black pigment stains abated .

在非裔美国人中用1%吡美莫司软膏治疗伴色素减退的脂溢性皮炎的先导性试验

Pilot trial of 1 % pimecrolimus cream in the treatment of seborrheic dermatitis in African American adults with associated hypopigmentation

在某些情况下，哈士奇会出现所谓的“雪鼻”或“冬天的鼻子”这种情况被称为“色素减退”。

Nose In some instances , Siberian Huskies can exhibit what is called " snow nose " or " winter nose " .

这个“综合症”包含长时间暴露在电脑热量下引起的皮肤色素减退。

The " syndrome " consists of a brownish discoloration of the skin caused by prolonged exposure to heat from the computer .

但传统的治疗方法如冷冻、同位素及硬化剂注射等易继发局部疤痕形成，色素减退，局部组织坏死等，实际临床受限。

The orthodox methods such as liquid nitrogen , isotope application , injection of sclerosing agent could result in scar , hypopigmentation and tissue necrosis .

临床上中药治疗相对安全无毒，因此可利用深色类中药治疗色素减退性疾病。

Clinically , Chinese herb therapy is relatively safe and nontoxic ; therefore dark color Chinese herbs can be used to treat the pigmentary loss diseases .

对白癜风的早期诊断及与其他色素减退斑相鉴别提供了参考依据。

In a nutshell , the application of PD has offered references to the early diagnosis of vitiligo and its differential diagnosis from other depigmentation diseases .

黑素细胞生成黑素的不足可以导致皮肤色素减退或脱失，促进黑素细胞的黑素生成是治疗色素脱失性疾病的策略之一。

The insufficient melanogenesis in melanocytes may result in hypopigmentation of the skin , and promotion of the melanogenesis in melanocytes is a strategy in treating depigmenting disorders .

深Ⅱ度皮肤色素减退者14例（70%），瘢痕增生率为25.0%（5／20）；

14 cases with deep 2nd degree wound had skin pigment faded ( 70 % ) . Hyperplastic scar formation rate was 25 . 0 % ( % / 20 ) .

白发的发生主要是由于毛囊中黑素细胞酪氨酸酶的活性降低或丧失，合成黑色素的功能减退，使毛干中缺乏黑色素而引起。

White hair is caused by the lack of melanin in hair , which results from loss of tyrosinase activity in melanoma cells of Hair follicle .

现代医学认为：白发是因毛球中黑素细胞形成黑色素的功能减退、酪氨酸酶的活性减低或丧失、毛干中缺乏黑色素而引起。

It is considered by modern medical theory that poliosis is originated from hypofunction of menalocyte forming melanin in bulbus pili , reduction and loss of tyrosinase activity and lack of melanin in scapus pili .

多因素分析结果显示：治疗效果与治疗次数、病程、激光强度和光斑大小有关（OR1，P0.05），术后出现暂时性色素沉着和色素减退23例（2.14%），无瘢痕发生。

The results of multi-factor analysis showed that the clinical effects were related to the treatment times , period of disease , energy and spot-size of laser ( OR1 , P0.05 ) . 23 cases ( 2.14 % ) appeared pigmented disorder temporary after treatment and no scar formation .

患者男，37岁。双上肢、上腰腹部及面颈部起丘疹、红斑、张力性水疱，色素沉着和色素减退相间，无自觉症状7年。

A 37-year-old male presented with asymptomatic poikilodermatous skin lesion , lichenoid papules and tense blisters on his upper extremities , waists , abdomen , face and neck for 7 years .

结果490例患者中，457例雀斑患者经1~3次治疗后均痊愈，约15%的患者治疗后出现暂时性色素沉着或色素减退，1~6个月自然消退。

Results All of the 457 freckles in 490 patients were cured after 1-3 times treatments . The skin reaction to the laser irradiation is slight . About 15 % of the patients showed transient hyperpigmentation or hypopigmentation , which could disappear spontaneously after 1-6 months .