致病因子

肝纤维化（hepaticfibrosis，HF）是各种不同致病因子引起慢性肝病进而发展为肝硬化的共有病理改变和必经途径，是肝脏对各种慢性损伤产生的一种修复反应。

Hepatic fibrosis is the common pathological changes of hepatic cirrhosis developed from varied kinds of chronic hepatic disease caused by many pathogenic factors .

MG存在着体液及细胞免疫异常，细胞因子分泌紊乱，干扰素γ（IFNγ）是重要的间接致病因子。

Humoral and cellular immune responses , and cytokine secretion are abnormal in MG . IFN & γ is one of important indirect pathogenic factors .

实验表明，ProteinA免疫吸附膜柱不仅具有良好的安全性能，对致病因子也有一定的去除能力，有望在实际临床中应用。

It is expected that Protein A membrane cartridge will be applied to the clinical therapy in the future .

金黄色葡萄球菌致病因子检测的PCR方法

Detection of staphylococcus aureus pathogenetic factor by PCR

结论：Hp自身可表达HSPB作为其致病因子；

Conclusion : Hp express HSP B as a pathogenic factor .

结论内毒素，耐热肠毒素（ST）是奇异变形杆菌主要的致病因子。

Conclusion Endotoxin and ST are important factors in the Virulence of Pomes mirabilis .

目前已证明，铝是DE肯定的、唯一的致病因子。

In present , it can be affirmed that aluminium is the only factor associated with DE.

铜绿假单胞菌（PseudomonasAeruginosa）致病因子受低于最小抑制浓度抗生素调节的研究

Regulation of Virulence-relevant Genes by Sub-inhibitory Concentrations of Antibiotics in Pseudomonas Aeruginosa

许多正链RNA病毒是严重危害人类健康的病原体，是造成经济植物动物死亡的致病因子。

Many plus-strand RNA viruses are the causative agents of some highly contagious diseases in human , animal and plant .

HGV是慢性肝炎的致病因子之一；

HGV is a responsible agent for chronic hepatitis .

多发性硬化（MS）由未知的环境过敏原或其它致病因子触发并影响遗传性易感人群的疾病。

Multiple sclerosis ( MS ) is triggered by unidentified antigens or other disease-causing agents in the environment and affects people who are genetically predisposed to the disease .

蛋白酶是嗜水气单胞菌（Aeromonashydrophila）的重要致病因子。

Extracellular protease was one of the important pathogenic factors of Aeromonas hydrophila .

溶血素是迟缓爱德华菌（Edwardsiellatarda简称ET）的重要致病因子。

Hemolysin is an important pathogenic agent of Edwardsiella tarda ( ET ) .

结论血浆Lp（a）浓度与颅内囊性动脉瘤发病有显著相关性，可能是导致动脉瘤形成的一种致病因子，也可以作为预测动脉瘤发病倾向的一个独立指标。

Conclusions The result indicate that Lp ( a ) is an independent risk factor for genesis of intracranial saccular aneurysms .

慢性NGU致病因子及治疗研究

Study on Therapy and Pathogenic Factors of Chronic NGU

据此认为，T-2毒素有可能成为OA发生的致病因子之一。

Therefore , the T-2 toxin produced by Fusarium in the grain is one of the pathogenic agents of OA .

其致病因子于2003年3月被鉴定为一种新的冠状病毒，被命名为SARS冠状病毒（SARS-CoV）。

In March 2003 , a novel coronavirus was identified as the etiological agent of SARS , which was termed as SARS-CoV .

结论HBsAg、HPV和HSV2可能不是KD的致病因子。

Conclusions Some viruses including HBsAg , HPV and HSV 2 may not be pathogenetic to the KD .

结论：TTV在原因不明性肝炎中感染率明显高于其他人群，其可能是本地区原因不明性肝炎的致病因子。

Conclusion : TTV infection will be one of the major causes of hepatitis of unknown etiology in this area .

KBD病儿血浆内的病毒可能就是KBD的致病因子。

The vinis in the plasmas of KBD chilren might be the causal factor for KBD .

HPV11型与HPV6型同属低危型HPV的代表病毒，为性传播疾病&尖锐湿疣的最主要致病因子。

HPV11 / 6 are representatives of the low-risk HPVs and mainly cause condyloma acuminatum .

其中，VP3蛋白质是鸡贫血病毒的致病因子，能选择性的诱导肿瘤细胞和转化细胞发生凋亡，但对人和鼠的正常二倍体细胞无影响，称为凋亡素（apoptin）。

Apoptin ( VP ,) can selectively induce apoptosis in human transformed and malignant cells but not in normal diploid cells .

结论：TTV感染是部分NAG型肝炎患者的致病因子，可导致慢性化。

Conclusion : TTV infection is the pathogenic factor to part of non-A-G hepatitis and it can lead to the disease chronic .

背景：空泡形成细胞毒素A（VacA）是幽门螺杆菌（H.pylori）的重要致病因子，研究VacA的致病机制有助于进一步明确H。

Background : Vacuolating cytotoxin A ( VacA ) is an important pathogenic factor of Helicobacter pylori ( H.pylori ) .

已经证明，Mip蛋白是一些动物病原微生物（例如嗜肺军团菌、沙眼衣原体、淋球菌等）的重要致病因子。

Mip proteins have been identified as important virulence factor in several animal pathogens such as Legionella pneumophila , Chlamydia trachomatis , Neisseria gonorrhoeae .

脂多糖（LPS）作为细菌表面的主要结构，参与对宿主的识别、侵染，是革兰氏阴性菌的主要致病因子。

As the primary structure on the surface of bacteria , LPS plays parts in recognition and infection of the host and is the major pathogenesis factor of gram-negative bacteria .

这表明福建省自然环境中存在脊灰Ⅱ型疫苗重组株病毒循环，此病毒可能是这类AFP病例的致病因子。

The study indicated that there were type ⅱ recombinant polioviruses circulating in the natural environment of the province and they possibly could be the pathogenic factor of AFP .

ACS发病后ET迅速升高，12h达峰值，是急性血管内皮损伤时一种强烈的内源性致病因子。

The plasma levels of ET increase to top at 12 h after episode in patients with ACS . ET is a strong pathogenic mediator after acute injury of endothelia .

创伤弧菌溶细胞素（Vibriovulnificuscytolysin，VVC）是创伤弧菌最重要的致病因子之一。

Vibrio vulnificus cytolysin ( VVC ) is one of the most important causative agents of V. vulnificus .

ET-1作为内源性致病因子与特异性ETR结合参与心血管疾病的发病过程，对心血管系统发挥重要的局部和整体调节作用，ET水平升高引起冠状动脉强烈收缩。

ET-1 , an endogenetic factor , combining with unique ETR , participates in the course of cardiovascular disease . The rising of ET can induce coronary artery contraction intensively .