膜磷脂

人老化红细胞膜磷脂含量及蛋白激酶C活性的测定

Assay of senescent human erythrocyte membrane phospholipid and protein kinase C

目的：通过测定葡萄糖－6－磷酸脱氢酶（G6PD）缺乏红细胞膜磷脂的含量及其不对称性的变化，研究G6PD缺乏对红细胞膜结构的影响。

Objective : To study the effect of G6PD deficiency on membrane phospholipid structures .

LPS激活膜磷脂代谢的反应特性表现出典型的酶促动力学特性。

The LPS activating effect of HUVEC membrane lipid showed a typical property of enzymatic dynamics .

线粒体凋亡途径包括细胞膜磷脂酰丝氨酸翻转、胞内活性氧水平升高、线粒体功能障碍、释放细胞色素c、激活半胱氨酸蛋白酶等环节。

This pathway including several processes such as cell membrane phosphatidylserine translocation , intracellular reactive oxygen species level increase , mitochondria dysfunction , cytochrome c release , caspases activation and so on .

DHA是遍及身体细胞膜磷脂的重要组成成分。

DHA is a vital component of the phospholipids in cell membranes throughout the body .

结论细胞膜磷脂PI、PC增高，PKCα/PKCβⅡ比例改变与大肠癌发生有关。

Conclusions The increases of PI and PC and PKC - α / PKC - βⅱ ratio change are related with colorectal cancer genesis .

目的探讨结直肠癌细胞膜磷脂变化与蛋白激酶C（PKC）同工酶表达的关系及对肝转移的影响。

Objective To study cell membrane phospholipid variation and protein kinase C ( PKC ) isoenzyme expression and their effects on hepatic metastasis of large intestinal carcinoma .

动态观察不同的药理性阻断剂对膜磷脂PtdIns（4,5）P2的代谢过程的影响特征

Spatiotemporal dynamics of pharmacological modulation of membrane PtdIns ( 4,5 ) P_2 metabolism by different agents

钙依赖性膜磷脂结合蛋白AnnexinⅡ对大鼠脊髓横断损伤的作用

Effects of calcium dependent phospholipids binding protein Annexin ⅱ on spinal cord transection injury model in rats

探讨了NIDDM患者红细胞膜磷脂成分与Na＋－K＋－ATP酶活性的变化。

Changes of phospholipid composition and Na + - K + - ATPase activity in erythrocyte membrane were studied in NIDDM patients .

细胞膜磷脂PIP2水解、细胞内钙释放与M通道功能关系的研究

The Study of the Relationship between Membrane PIP_2 Hydrolysis , Intracellular Ca ~( 2 + ) Release and M Channel Function

于超负荷后随即卡托普利干预者，心肌线粒体膜磷脂结构改变与对照组比较变化不大（P＞0.05），心室作功能力却进一步降低；

In the group treated with captopril post fistula immediately , compared with the control , even the localization of mitochondrial MPLs injury of myocardial cells had not marked change ( P > 0 . 05 ), the ventricular performance was further decreased ;

神经节苷脂GM1对乙醇引起的神经膜磷脂脂肪酸参入变化的影响

Effects of Ganglioside GM1 on Ethanol Induced Changes in the Incorporation of Free Fatty Acids into Synaptosomal Membrane Phospholipids

首次揭示酵母菌细胞膜磷脂脂肪酸组成对影响质膜ATP酶对乙醇刺激的响应。

This work reveals for the first time that fatty acid composition of phospholipids in plasma membranes of yeast significantly affects the response of plasma membrane ATPase to ethanol stimuli .

提示，老化KC膜磷脂功能明显异常，VE对其具有显著的保护作用。

The results indicate that aged KC has a disordered membrane phospholipid function and VE has a prominent protective effect on it .

膜磷脂含量无明显改变，但膜胆固醇显著增加，磷脂/胆固醇之比显著降低，膜Ca~（2+）-Mg~（2+）ATP酶活力显著升高。

The cholesterol was significantly increased , but the phospholipids unchanged , resulting in a significantly reduced P / C ratio . The activity of Ca2 + - Mg2 + ATPase elevated markedly .

结论DEX诱导小鼠胸腺细胞发生典型细胞凋亡和线粒体去极化增强，在该进程中，线粒体去极化增强发生在细胞膜磷脂酰丝氨酸外翻之前。

Conclusion DEX can induce typical apoptosis and mitochondrial depolarization of thymocytes , and the mitochondrial depolarization occurs before exposure of membrane phosphatidyl serine .

结果显示conA刺激后膜磷脂和conA受体的扩散系数和荧光恢复率均较静息状态的巨噬细胞明显降低，磷脂流动性的变化与conA受体流动性的变化呈正相关。

The results showed that the diffusion coefficient and fluorescence recovery of macrophages membrane phospholipid and Con A receptors evidently lowered after being stimulated by Con A than in resting conditions .

阿霉素对大鼠心肌细胞膜磷脂损伤及CoQ（10）的保护作用

Membrane phospholipids injury in myocardial cells of adriamycin rats and the protective effects of coq_ ( 10 ) on it

研究了紫草多糖对S180荷瘤小鼠红细胞膜磷脂脂肪酸含量及脂肪酸组分的影响。

To study the effects of crude polysaccharide from arnebia euchroma ( Royle ) Johns ( ZCP ) on phospholipids fatty acid content diversity and of erythrocyte membrane for S180 mice .

目的探讨小鼠肝线粒体膜磷脂组成的随龄变化及红花总黄素（SY）对肝线粒体膜的保护作用。

Objective To investigate the age related changes of phospholipid contents in hepatic mitochondria membrane of mice and the protective effect of safflower yellow ( SY ) on hepatocytic mitochondria .

细胞膜磷脂对LPS-CD14结合的影响

Effect of cellular membrane phospholipids on LPS-CD14 binding

我们观察了45例高血压病（EH）患者红细胞膜磷脂，脂质过氧化及有关酶水平和血液流变各指标变化及相互关系。

Abstract The changes and interrelation of erythrocyte membrane phospholipids ( EPL ), serum lipid peroxide ( LPO ) and related enzymes , and blood viscosity were studied in 45 cases of essential hypertension ( EH ) and 30 normal subjects .

本文用FRAP（FluorescenceRecoveryAfterPhotobleaching）技术，测量了静息状态和刀豆素A刺激不同时间后巨噬细胞膜磷脂、conA受体扩散系数和荧光恢复率的变化。

The diffusion coefficient and fluorescence recovery of macrophage membrane phospholipid and Con A receptors in resting condition and after stimulated by Concanavalin A ( Con A ) for different time were measured by FRAP ( fluorescence recovery after photobleaching ) technique .

结果：IG小鼠心肌线粒体大量破坏，CCO和SDH活性降低，膜磷脂严重缺失、定位改变（P＜0.05～0.01）。

Results : As compared to CG , a large number of mitochondria of IG was damaged , the activities of CCO and SDH of mitochondria declined , the apparent mitochondrial membrane phospholipid deletion and localization change were observed ( P0.05 ~ 0.01 ) .

本文对膜磷脂脂肪酸组成变化的意义结合先前的实验结果进行了讨论，认为在PPS、ASPS的抗肿瘤机理中，细胞膜磷脂生化特性的改变是重要环节。

The significance of PPS and ASPS affecting membranes fatty acid composition was discussed combining with our previous results . We think the change of cell membrane phospholipid biochemical feature is a important link .

结果：感染组小鼠心肌线粒体大量破坏，膜磷脂严重缺失、定位改变，CCO和SDH活性降低，ATP、ADP和AMP含量下降。

Results : A large number of mitochondria were damaged in infection group , the apparent mitochondrial membrane phospholipid deletion and localization change were observed , the activities of CCO and SDH in mitochondria declined obviously , and the contents of ATP , ADP as well as AMP declined notably .

结果：CVB3感染第7天心肌线粒体增生、肿胀，CCO和SDH活性明显降低（P<005～001），膜磷脂定位无明显变化；

Results : On the 7th day after virus infection , the myocardial mitochondria swelled mildly , the mitochondrial number increased and the activities of CCO and SDH of mitochondria declined obviously ( P < 0.05 ~ 0.01 ), but the mitochondrial membrane phospholipid localization had no notable change .

脂皮素1（LC1）是钙依赖性的膜磷脂结合蛋白，介导糖皮质激素的抗炎作用。

Lipocortin 1 ( LC 1 ) is a calcium dependent phospholipid binding protein which is acts as one of the ` second messengers'of the anti inflammatory actions of the glucocorticoids . The sequence of human lipocortin 1 gene was cloned by the RT PCR method .

膜磷脂含量对线粒体氧化磷酸化的影响

Effect of the contents of membrane phospholipid on mitochondrial oxidative phosphorylation