脱氧胆酸

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  • deoxycholic acid
脱氧胆酸脱氧胆酸
  1. 胆汁中结合脱氧胆酸(DCA)含量和比例增加。

    The level and proportion of the conjunct deoxycholic acid ( DCA ) in the bile was increased .

  2. 黑索金组血清石胆酸(LCA)、脱氧胆酸(DCA)、鹅脱氧胆酸(CDCA)升高,显著性检验有差异;

    Lithocholic acid ( LCA ), deoxycholic acid ( DCA ) and chenodeoxycholic acid ( CDCA ) in serum ascended when workers exposed to hexogen , statistic differences were found ;

  3. 方法:脱氧胆酸钠逆行胆胰管注射诱发大鼠AP模型。

    METHODS : AP model was induced by retrograde injection of sodium deoxycholate into bilipancreatic duct in rats .

  4. 脱氧胆酸钇络合物的EXAFS和FTIR表征

    Characterization of yttrium deoxycholate complex with EXAFS and FTIR

  5. 方法:用胰胆管内注射甘脱氧胆酸,结合静脉输注蛙皮素方法复制大鼠ASP模型。

    Methods : The ASP model was produced by intravenous infusion of cerulein with the combination of intraductal administration of glycodeoxycholic acid .

  6. 用EXAFS,FTIR以及ICP等实验方法,对脱氧胆酸钇的结构进行了初步探讨。

    Coordination structure of yttrium deoxycholate complex has been studied by EXAFS , FTIR and ICP methods .

  7. 黄连素对脱氧胆酸诱导下人结肠癌细胞AP-1、COX-2表达的影响

    The Effects of Berberine on AP-1 , COX-2 Expression of Human Colon Cancer Cells Induced by Deoxycholic Acid

  8. 复合促吸收剂脱氧胆酸钠+氮酮+脑磷脂能在3h内达到最佳促吸收效果,吸收率为81.3%。

    The compound administration of absorption enhancers , deoxycholate sodium plus azone plus cephalin had the absorption rate of 81.3 % .

  9. 推注5%牛磺脱氧胆酸钠(0.5ml/kg体重)复制SAP模型。

    SAP models are induced by injecting 5 % sodium deoxycholate ( 0.5ml/kg weight ) .

  10. 黄连素对脱氧胆酸诱导的HT-29人结肠癌细胞增殖的抑制作用及机制研究

    Study in the effects of berberine on inhibiting HT-29 human colon cancer cell proliferation induced by deoxycholic acid

  11. 甘氨脱氧胆酸盐诱导人正常肝细胞HL-7702凋亡及其机制的研究

    Apoptosis mechanism of cultured human hepatocyte HL-7702 induced by glycodeoxycholate

  12. 目的探讨熊脱氧胆酸(ursodeoxycholicacid,UDCA)对胆道梗阻肝脏部分切除(PH)后肝细胞再生的影响。

    Objective To investigate the effect of ursodeoxycholic acid ( UDCA ) on liver regeneration after 70 % partial hepatectomy ( PH ) in bile duct obstructive ( BDO ) rats .

  13. 目的考察口服胰岛素聚乳酸纳米粒(INSPLANP)在胃肠道不同部位的吸收以及吸收促进剂脱氧胆酸(DOC)对吸收的影响。

    AIM To investigate the effect of DO C ( deoxycholic acid ) on the absorption of INS-PLA-NP [ insulin-loaded poly ( lactic acid ) nanoparticles ] in different sites of gastrointestinal tracts .

  14. 目的:探讨脱氧胆酸对结肠癌细胞的作用,以及对环氧合酶2表达和前列腺素E2合成的影响。方法:在结肠癌细胞系HT29中加入脱氧胆酸,分别培养6、12、24、48h。

    Objective : To discuss the effects of deoxycholate acid ( DCA ) on cyclooxygenase-2 ( COX-2 ) expression and prostaglandin E2 ( PGE2 ) level in cultured Colonic Cancer Cell line HT_29cells .

  15. 以脱氧胆酸为spacer,通过三光气桥连各种芳胺,合成了新的氨基甲酸酯型分子钳受体1~4.这些化合物的结构经IR,1HNMR和元素分析所证实。

    New chiral molecular tweezers 1 ~ 4 have been synthesized by using deoxycholic acid as a spacer to bridge the different aromatic amines . Their structures were confirmed by IR , 1H NMR and elemental analysis .

  16. 目的观察甘氨脱氧胆酸(GDC)对大鼠肝细胞钙激活性钾通道(KCa)开放概率的影响。

    Objective To investigate the influence of glycodeoxycholate ( GDC ) on open probability of calcium activated potassium ( K Ca ) in rat hepatocytes .

  17. 通过胰胆管逆行注射不同浓度的脱氧胆酸钠,制作急性水肿性胰腺炎(AEP)和急性坏死性胰腺炎(ANP)模型。

    The models of acute edematous pancreatitis ( AEP ) and acute necrotizing pancreatitis ( ANP ) were established by retrograde injection of different concentration of sodium deoxycholate into the common bile-pancreatic duct .

  18. 研究脱氧胆酸钠和溴化四丁铵的混合态表面活性剂涂层烷基键合硅胶(ODS)固定相的制备和它在手性对映体分离中的应用。

    The present paper deals with the preparation of surfactant ( deoxycholic sodium and tetrabutylammonium bromide mixture ) coat bonded to silica gel with alkyls as well as its application to the separation of chiral enantiomers .

  19. 结论:TritonX-100及脱氧胆酸钠化学处理方法,可有效清除人类周围神经中的细胞及髓鞘,萃取粗大和长段的去细胞神经;

    CONCLUSION : When treated with Triton X 100 and deoxycholate sodium , cells and myelin sheath can be effectively cleared from human peripheral nerve , thus leaving a long and thick acellular nerve .

  20. 以支撑磷脂双层膜(supportedbilayerlipidmembrane,s-BLM)作为生物膜模型,采用循环伏安法和交流阻抗技术研究了脱氧胆酸钠(sodiumdeoxycholate,NaDC)与s-BLM的相互作用。

    In this paper , supported bilayer lipid membrane ( s-BLM ) was served as a biomembrane model . The interaction between sodium deoxycholate ( NaDC ) and s-BLM was investigated by means of cyclic voltammetry and ac impedance spectroscopy .

  21. 方法胰胆管逆行注射5%脱氧胆酸钠(DCA)复制大鼠AP模型,观察胰腺和肺组织病理学改变,使用RT-PCR法检测肺组织中MIP-2mRNA、TNF-αmRNA的表达。

    Rat AP model was induced by intraductal administration of 5 % sodium deoxycholate ( DCA ) . The severity of pancreatitis and lung injury were measured by histopathologic scores . MIP-2 mRNA and TNF - α mRNA in lung were measured by semi quantitative RT-PCR .

  22. 结果:单独使用时,胆盐Ⅲ号(BSⅢ)的促吸收效率最低,3h仅为11.8%,脱氧胆酸钠的促吸收率最高,3h为59.7%;

    RESULTS : Three hours after the single administration of each absorption enhancer , the absorption rate of trypsin with the aid of the bile salt ⅲ was the lowest ( only 11.8 % ) and the deoxycholate sodium was the highest ( 59.7 % ) .

  23. 以脱氧胆酸钠(DOC)洗涤包涵体,然后用N&十二烷基肌氨酸钠(SKL)溶解,将溶解包涵体进行透析复性。

    The inclusion bodies were washed with Deoxycholic acid Sodium Salt ( DOC ) for several times , and then dissolved in N-Lauroyl Sarcosine Sodium ( SKL ) for denaturant . After that , a good renature result was obtained by dialysis .

  24. 本论文制备了亚油酸修饰壳聚糖(LACH)、脱氧胆酸修饰壳聚糖(DACH)两种壳聚糖脂复合物,并检测了合成的复合物的细胞毒性;

    Two kinds of chitosan derivatives , linoleic acid modified chitosan ( LACH ) and deoxycholic acid modified chitosan ( DACH ), are synthesized and the cytotoxicity of these compounds is tested in this thesis .

  25. 结果含桉油醇、癸酸钠、脱氧胆酸钠和薄荷醇的INSSOL(5U·kg-1)均可降低血糖(P005),而桉油醇的作用最明显,最大降糖百分数为388%(P001)。

    Results INS SOL ( 5 U · kg - 1 ) containing eucalyptol , sodium caprate , sodium deoxycholate and menthol significantly decreased the blood glucose level ( P 0 05 ), and eucalyptol appeared to be more effective ( 38 8 % , P 0 01 ) .

  26. 目的:探讨熊脱氧胆酸(UDCA)和鹅脱氧胆酸(CDCA)对胆汁分泌、谷氨酸脱氢酶(GLDH)和线粒体膜结构的作用,以及UDCA的线粒体膜保护作用。

    Objective : To investigate whether enzyme release caused by chenodeoxycholic acid ( CDCA ) can be prevented by ursodeoxycholic acid ( UDCA ), and to study the effects of bile acids on bile secretion , glutamate dehydrogenase ( GLDH ) release and mitochondrial membrane structure .

  27. 脱氧胆酸诱导正常人食管黏膜上皮细胞凋亡及其机制探讨

    Deoxycholate induces apoptosis in cultured normal human esophageal mucosal epithelial cells

  28. 鹅脱氧胆酸损害肝细胞机制初探

    A preliminary study on the mechanism by which chenodeoxycholate injures liver cells

  29. 金属-脱氧胆酸凝胶体系中的分形沉淀及维数计算

    Fractal Precipitation and Dimension Calculation in Metal Deoxycholate Acid Sol Gel System

  30. 熊脱氧胆酸抑制兔胆结石形成的作用及机制

    The mechanism of the inhibitory effect of ursodeoxycholate on gallstone formation in rabbits