肿瘤免疫治疗

DNA疫苗与肿瘤免疫治疗

DNA vaccines and cancer immunotherapy

CD4~+CD（25）~+调节性T细胞在肿瘤免疫治疗中的价值及应用前景

The Prospects of the usage of CD_4 ~ + CD_ ( 25 ) ~ + regulatory T cells in cancer immunotherapy

DC的这一固有免疫功能在肿瘤免疫治疗中具有重要的意义。

The unique innate immune functions of DCs are crucial in tumor immunotherapy .

DC瘤苗的制备与应用成为了肿瘤免疫治疗的研究热点。

The preparation and application of DC vaccines became immune therapy of cancer research hotspot .

结论DC瘤苗以其安全、有效、易行的特点，将会在肿瘤免疫治疗中具有良好的应用前景。

Conclusion DC vaccine is promising in tumor immunotherapy owing to its safety , efficiency and convenience .

目前在抗肿瘤免疫治疗中，最常用的负载DC的方式有应用抗原肽和全抗原两种。

DC vaccines are always made by been pulsed with tumor peptide or complex antigen in anti-tumor immunotherapy .

目的探索点突变p53肽诱导细胞免疫应答的可能性，为其作为肽疫苗用于肿瘤免疫治疗提供实验依据。

Objective To explore the possibility of inducing cell-mediated immune response with p53 peptides .

DC在抗肿瘤免疫治疗中的应用已成为肿瘤主动特异性免疫治疗的研究热点之一。

The application of DCs in immunotherapy of tumor has become a research focus in the field of initiative specific immunotherapy of tumor .

Poly（I：C）在肿瘤免疫治疗中的作用已被广泛论证。

The effect of poly ( I : C ) in tumor immune therapy have been well demonstrated .

树突状细胞（DC）是专职的抗原递呈细胞（APC），是唯一能激活纯真T细胞的APC，在肿瘤免疫治疗中起重要作用。

Dendritic cells ( DCs ) are a specialized system of antigen - presenting cells .

基于NK细胞的肿瘤免疫治疗研究进展

Progress in NK cell-based immunotherapy of tumor

近年来随着人们了解的深入，基于DC的肿瘤免疫治疗方法越来越受关注。

With the intensive understanding to the biological behaviors of DC , people pay more and more attention to the role of DC in cancer immune therapy .

DC在抗肿瘤免疫治疗策略中的变迁则源于对其抗肿瘤免疫机制的认识，就其近年的研究进展作一综述。

The development of technique to generate DCs has recently led to new approaches to cancer immunotherapy that will be the anti tumor mechanisms of this review .

结论：无血清DCs专用培养基可以在体外快速培养临床级DCs，为肿瘤免疫治疗奠定基础。

Conclusion : Clinical grade DCs can be cultured rapidly in serum-free DC medium and can be used in tumor immunotherapy .

结论：在肿瘤免疫治疗中，脉冲致敏DC一定要用灭活的肿瘤细胞作为抗原刺激物，才能有效地完成抗原递呈功能。

Conclusion : DC with pulse sensitization should use deactivated tumor cells as antigen stimulator substance , then , effectively perform antigen-presenting function in immune treatment of antitumor .

CIK细胞在肿瘤免疫治疗中的作用

Study on Anti-tumor Effects of CIK Cells in Tumor Immunol Therapy

A-NK细胞联合IL-2，IL-12在肿瘤免疫治疗中的作用

The Function on Tumor Immunotherapy with A-NK Cells Combined with IL-2 and IL-12

大量的临床试验研究也表明DC瘤苗抗肿瘤免疫治疗具有良好的应用前景[6]。在人体的抗肿瘤免疫机制中，T细胞介导的细胞免疫为主要方式。

Most clinic trials indicate that DC immunotherapy has a favorable perspective [ 6 ] . In our antitumor immunity mechanisms , the cytoimmunity mediated of T cell is main way .

目的探讨合成含CpG基序的寡核苷酸（cpGODN）在肿瘤免疫治疗中的研究。

Objective To study the immunotherapy role of CpG ODN ( CpG oligodeoxynucleotide ) on tumor .

目的：研究CpG联合非复制重组痘苗病毒在肿瘤免疫治疗中的效果。

Objective : To investigate the antitumor effect of CpG-ODN combining non-replicating recombinant vaccinia virus in tumor immunotherapy .

Mac-1的结构与功能及其在肿瘤免疫治疗中的作用

Structure and function of Mac-1 and its role in cancer immunotherapy

因此，IL-4在抗肿瘤免疫治疗方面具有很大潜力，它作为肿瘤免疫调节剂已进入Ⅱ期临床试验。

So IL-4 has a great potency in antitumor immunotherapy , as a tumor immuno-regulator , IL-4 has been applied into the second clinical trial .

目的以B7-H1为靶点，研制肿瘤免疫治疗蛋白疫苗。

Objective To prepare protein vaccine for immunotherapy of tumors using B7-H1 as a target .

临床前及临床研究正在开发基于TLRs信号通路的肿瘤免疫治疗。

The strategy of cancer immunotherapy based on TLRs signaling is developing in preclinical and clinical studies .

补体调节蛋白CD46、CD55及CD59在肿瘤免疫治疗中的研究进展

Research Progression on Complement Regulatory Proteins CD46 , CD55 , and CD59 in Tumor Immunotherapy

结论建立了稳定表达外源性p53基因的U14细胞系，为进一步研究p53基因用于肿瘤免疫治疗奠定基础。

Conclusion The U_ ( 14 ) cell line stably expressing p53 gene is established , and it can be used for the further study of p53 gene-immunotherapy of tumor .

CIK细胞治疗作为过继免疫治疗方法，具有广阔的临床应用前景，有可能成为肿瘤免疫治疗的新策略。

CIK cell therapy as a method of adoptive immunotherapy has a broad prospect for clinical application and may become a new strategy for tumor immunotherapy .

以exosome为基础的肿瘤免疫治疗研究进展

Research advance on exosome-based cancer immunotherapy

HSPs／肽复合物疫苗有可能成为众多肿瘤免疫治疗方法以及肿瘤综合治疗方法中可行的选择之一。

This experimental study was aimed to verify if HSPs / peptides compound vaccine can be used as a new methods for immunotherapy of bone sarcoma .

结论：成功地将外原性HSP70基因转染到大鼠胶质瘤C6细胞中并进行表达，为HSP70在肿瘤免疫治疗中的应用提供了实验材料。

Conclusion : The HSP_ 70 gene was transfected and expressed into C_6 cell successfully , which laid a foundation for the research of HSP_ 70 in the tumor immunotherapy .