细胞外基质

我们的目的是探讨血管生长因子（IL-8，PDGF，VEGF），免疫调节因子（IFN-α-2b，IFN-γ）和细胞外基质（collagenⅠ，Ⅲ）在EM中的作用。

Our purpose is to determine the effect of angiogenesis growth factors ( IL-8 , PDGF , VEGF ), immunomodulator ( IFN - a - 2b , IFN - Y ) and ECM ( collagen I > III ) on developing of endometriosis .

糖尿病大鼠肾组织TGF-β1及细胞外基质表达

Express of TGF - β _1 and ECM in STZ Diabetes Rats

糖尿病患者的C反应蛋白与细胞外基质变化

The change of C-reactive protein and extracellular matrix in diabetes mellitus patients

其中对组织屏障&细胞外基质（extracellularmatrixECM）的降解是肿瘤发生转移的重要步骤。

Degradation of extracellular matrix ( ECM ) is a key step for metastasis .

在此过程中，细胞外基质（Extracellularmatrix，ECM）的降解是肿瘤侵袭性的标志。

In the course , degradation of extracellular matrix ( ECM ) is the characteristic of tumor invasion .

基质金属蛋白酶家族（Matrixmetalloproteinases，MMPs）是降解细胞外基质的主要酶类之一。

Matrix metalloproteinases ( MMPs ) is a main enzyme to degrade extracelluar matrix .

细胞外基质（ECM）积聚是肾脏纤维化的最终途径。

Extracellular matrix ( ECM ) accumulation is the final pathway to renal fibrosis .

肾络宁对IgA肾病大鼠肾间质细胞外基质代谢的影响

Effect of Shen Luo-ning on Extracellular Matrix Metabolism of Kidney Interstitial Tissue in IgA Nephrosis Rats

目的观察细胞外基质（ECM）在肺老化中的作用。

Objective To evaluate the role of extracelluar matrix ( ECM ) in aging rat lungs .

细胞外基质（extracellularmatrixECM）合成和降解失衡，造成大量积聚是引起肾间质纤维化的主要原因。

The accumulation of extracellular matrix ( ECM ) resulting from the unbalance of synthesis and degradation is the main cause of TIF .

大量研究显示，细胞外基质（extracellularmatrixECM）的降解是肿瘤侵袭和转移过程中关键的一步。

Many studies displayed that degradation of extracellular matrix ( ECM ) was the capital step in the process of tumor invasion and metastasis .

整合素αVβ3在细胞外基质调控人黑色素瘤MMP-2表达和活化中的作用

Effect of integrin α _V β _3 on expression and activation of matrix metalloproteinase-2 of human melanoma cells regulated by extracellular matrix

推想糖尿病肾病的肾组织的细胞外基质（ECM）的堆积与MMP-2表达降低相关。

We considered the expression of MMP-2 was decreased in extracellular matrix ( ECM ) of diabetic nephropathy .

肝纤维化是由于肝脏胶原等细胞外基质（extracellularmatrixECM）合成与降解失衡，导致在肝内过量沉积。

Hepatic fibrosis is caused by an imbalance between the synthesis and degradation of extracellular matrix ( ECM ), which leads to its excessive deposition .

电镜显示NC组大鼠肾小球细胞外基质与系膜细胞分布正常，毛细血管腔开放；

Electron microscope showed that thickness of glomerular basement membrane and mesangial cells were normal , capillary lumen was open in Group NC , but mesangial proliferation ;

PPARγ1对系膜细胞外基质生成的抑制作用及其机制

The Inhibitive Effects and Mechanisms of PPAR γ 1 on the Extracellular Matrix of Mesangial Cells

基质金属蛋白酶（MMPs）是一大类锌依赖性内肽酶家族，能降解一种或几种细胞外基质（ECM）。

Matrix metalloproteinases ( MMPs ), zinc dependent proteolytic enzymes , can cleave extracellular matrix ( ECM ) .

目的：探讨细胞外基质蛋白1（extracellularmatrixprotein1，ECM1）在肿瘤组织中的表达及意义。

Objective : To investigate the expression and significance of extracellular matrix protein 1 ( ECM1 ) in tumor tissues .

用免疫组化及原位杂交观察肾脏TGFβ1表达及细胞外基质（ECM）沉积。以计算机图象分析进行半定量比较。

The expressions of TGF β 1 and extracellular matrix protein and TGF β 1mRNA were analyzed by immunohistochemistry and in situ hybridization .

肝纤维化的病理学基础为细胞外基质（Extracellularmatrix，ECM）合成增加，降解减少，导致胶原过度沉积。

The pathological foundation of liver fibrosis includes the increased synthesis and decreased degradation of extracellular matrix ( ECM ), which leads the excessive deposition of collagen .

柴胡皂甙对FSC激活及合成细胞外基质的实验研究

A Clinical Study on the Saikosaponin on FSC Activation and Extracellular Matrix Synthesis

结论SIS作为一种天然的细胞外基质材料，可显著提高胰岛细胞冷冻保存后的回收率，减少冻存胰岛细胞复苏时的死亡，并改善胰岛细胞的功能。

Conclusion Co-culture of cryopreserved rat islets with SIS can increase the recovery of islet cells and improve their function .

结论：酶谱法是研究HSC调节肝纤维化过程中细胞外基质（ECM）代谢的有效手段。

Conclusion : Zymography is suitable for the studies on the role of HSC in the regulation of extracellular matrix turnover .

I型胶原是纤维化中细胞外基质（ECM）的主要成分之一，其表达受转录、转录后水平多重调控。

Type I collagen is a major constituent of extracellular matrix produced when fibrogenesis and its expression is controlled by transcription and post-transcriptional .

肾组织细胞外基质的沉积明显减少及肾组织PAI-1的表达降低（P<0.05）；

The PAI-1 expression and deposition of extracellular matrix in renal tissue significantly decreased ( P < 0.05 ) .

探讨压力负荷增高性心肌肥厚时心肌胶原网络及心肌细胞外基质金属蛋白酶（MMPs）活性的变化。

To examine changes of collagen network and Matrix Metaloproteinases ( MMPs ) activity in hypertrophied rat myocardium .

透明质酸（HA）是一种带有负电荷的天然多糖，是细胞外基质的主要成分，具有优异的生物相容性。

Hyaluronic acid ( HA ), a natural polysaccharide , is the major constituent of the extracellular matrix ( ECM ) . HA exhibits excellent biocompatibility and biodegradability .

其主要特征表现为以胶原为主要成分的细胞外基质（extra-cellularmatrix，ECM）合成增多、降解相对不足而过量沉积。

The main character of the diseases is the deposition of extra-cellular matrix ( ECM ) because of its excess synthesis and decreased degradation .

TGFβ1是一种有多种功能的蛋白多肽，它既能刺激细胞外基质的合成，又能抑制新合成的细胞外基质的降解，还能增加血管的形成。

TGF-P 1 is a polypeptide with many biologic functions , which promotes the synthesis of extracellular matrix ( ECM ) and angiogenesis , and inhibits ECM catabolism .

腺病毒介导TIMP-2基因转染抑制大鼠腹主动脉细胞外基质降解的实验研究

Experimental Study of Inhibiting Effect of TIMP-2 Gene Transfected by Adenovirus on Extracellular Matrix of Rat Abdominal Aorta