类脂

细胞色素C在阴离子修饰的盐桥支撑双层类脂膜上的电化学行为及其应用

Electrochemical Behavior of Cytochrome C on Salt Bridge Supported Bilayer Lipid Membranes Modified with Anionic Sites and Its Analytical Application

LPS由类脂A、核心多糖和O-特异性多糖三部分组成。

The LPS molecule can be divided into three parts : lipid A , core polysaccharides and O-antigen repeats .

所以，研究C（60）修饰的双层类脂膜光电方面的特性具有重大意义。

Therefore , study of photoelectric and properties of C60 modified BLM has the great significance .

目前，植硅体类脂物的GC-MS分析数据很少报道。

To date , the GC-MS analysis of lipids in the phytolith is rarely reported .

采用循环伏安法研究了细胞色素C在月桂酸阴离子修饰的盐桥支撑双层类脂膜上的氧化还原反应；

The redox behavior of cytochrome C on salt bridge supported bilayer lipid membranes ( BLMs ) modified with lauric acid anionic sites was studied by means of cyclic voltammetry .

此外，在Clone50的腹水中检出高滴度的抗Re－LPS和抗类脂A抗体。

High levels of anti - LPS and anti-lipid A antibodies were detected in Clone 50 ascites .

抗类脂A治疗梗阻性黄疸病人血液IL-6、IL-8水平的影响

Changes of plasma IL 6 and IL 8 level during anti endotoxin treatment in patients with obstructive jaundice

对盐桥支撑双层类脂膜的特性、细胞色素C的电化学反应动力学以及有关影响细胞色素C循环伏安行为的各种因素进行了详细探讨；

The characteristics of salt bridge supported BLMs , the electrochemical reaction mechanism of cytochrome C and the effects of various factors on its cyclic _ voltammetric behavior were investigated in details .

脂多糖结合蛋白（LBP）是存在于正常人和动物血清中的一种糖蛋白，属于I型急性期反应蛋白，与脂多糖（LPS）的类脂A部分具有高度亲和性。

Lipopolysaccharide binding protein ( LBP ) is a 60 kD acute phase glycoprotein capable of binding the LPS .

生育酚（tocopherol）俗称维生素E，是仅由光合生物合成的一类脂溶性的强抗氧化物质，为人体所必需。

Tocopherols , commonly known as vitamin E , are a group of lipid-soluble antioxidants synthesized only by plants and other photosynthetic organisms .

而缺乏多糖链终末片断的内毒素Rc，Rd和Re及类脂A均末能造成肠源性感染。

Whereas those endotoxin preparation lacking the terminal-portions ( Rc , Rd , Re and lipid A ) did not induce gut origin infection .

结果妇女和儿童静脉血中多氯联苯平均含量（G）分别为176、192ng/g（类脂计）。

Results The mean content ( G ) of PCBs is 176ng / g lipid in the venous blood of the women and 192 ng / g lipid in that of the children .

类脂A中长脂肪链的紧密叠加以及LPS的疏水部共同形成了细菌的通透性屏障。

Tight stacking of the long-chain fatty acids of lipid A , the hydrophobic anchor of LPS , forms a permeability barrier around the cell .

生物膜（biomembranes）是由具有双层结构的类脂分子和镶嵌在其中的膜蛋白所共同构成的。

Biomembranes are composed of lipid bilayers and membrane proteins .

毫无疑问，这些令人兴奋的发展的灵感来源于生物界，例如，自然界使用自组装策略创造复杂的、有功能的结构，除了上述细胞膜的类脂双层，还有诸如手性蛋白质及DNA。

Without question , the inspiration for these exciting developments come from the biological world , where , for example , Nature uses self-assembly as a strategy to create complex , functional structures such as viral protein coatings , and DNA .

类脂双层膜BLMs的镶嵌修饰与应用

Modifications and Applications of Bilayer Lipid Membranes

另一方面，维他命A、D、E和K这类脂溶维他命却能在人体里停留很长一段时间，因而就没必要经常地去服用含有脂溶性的食品。

On the other hand , the fat-soluble vitamins , vitamins A , D , E and K stay in the body for long periods of time and so there is no need to take foods containing them so often .

ox-LDL对大鼠血管平滑肌细胞中诱生型一氧化氮合酶基因表达及一氧化氮产量的影响和α-类脂酸抗氧化作用的研究

Effects of ox-LDL on iNOS Gene Expression and NO Production in Rat Vascular Smooth Muscle Cells and Study on Antioxidation of α - Lipoic Acid

脐带血中13种PCBs总浓度的最大值为102ng/g类脂，几何均数为56.9ng/g类脂。

While the maximum and geometric mean concentrations of the 13 PCBs in cord blood were 102 ng / g lipoid and 56.9 ng / g lipoid respectively .

维生素E又称生育酚，仅由光合生物合成，可以清除生物体内的活性氧和自由基，是人体必需的一类脂溶性维生素，具有重要的抗氧化功能。

Tocopherols , commonly known as vitamin E , are a class of lipid-soluble antioxidants synthesized only by photosynthetic organisms . Tocopherols are essential to human because they perform numerous critical functions including quenching and scavenging various reactive oxygen species and free radical .

C（60）分子的亲脂疏水特性以及良好的电子输运能力使其修饰的双层类脂膜（BLM）在发展新型生物传感器和电子器件方面具有巨大的潜力。

C60 molecule has a unique hydrophobic dynamic feature and it is also a good electron carrier . So the C60 modified BLM provides the great possibility of the development of a new generation of biologic sensors and electronic devices .

Bola型两亲化合物分子因具有中部是疏水基，两端为亲水基团的特殊结构，可在水中聚集形成单层类脂膜（MLM）和单分子层囊泡（MLM囊泡）。

S : Bolaform amphiphiles can form monolayer lipid membrane ( MLM ) and monolayer lipid membrane vesicle ( MLM vesicle ) in water .

CH（50）和C3有助于急性肾炎、类脂性和肾炎性肾病的鉴别及肾炎时判断病情和估计予后。

It was found that the determination of serum CH50 and C3 are helpful in the differential diagnosis of acute glomerulonephritis , lipoid nephrotic syndrome and nephritic nephrosis , and it is also helpful to evaluate the severity of acute nephritis and make a prognosis .

实验证实30%双氧水能裂解LPS类脂A还原端C1位上的磷酸基团，而大蒜作用机理较复杂，除水解作用外，还能螯合LPS分子，影响LPS单体发挥作用。

The mechanism of H on LPS degradation was fractionization of phosphoryl in position 1 from lipid A , while that of G was complex , it could bound LPS molecule and influenced its effect besides LPS hydrolysis .

膜类脂双层实际上是可流动的而且与橄榄油有一致性（粘度约1mPa·s）。

The lipid bilayer of the membrane is actually fluid and has the consistency of olive oil ( viscosity ~ 1cP ) .

脂多糖（LPS）是内毒素的主要成分，来源于革兰氏阴性菌细胞壁的外膜，由核心寡聚糖、特异性多糖与类脂A组成，其中类脂A是LPS的活性部位以及毒力中心。

The main component of the endotoxin , lipopolysaccharide ( LPS ) derived from the outer membrane of Gram-negative bacteria cell wall is composed by the core oligosaccharide , specific polysaccharide and lipid A which is the active site and the center virulence of LPS .

Ⅰ期煤工尘肺的总类脂、磷脂显著高于对照组（P<0.05），而Ⅱ期煤工尘肺的SiO2含量显著增高（P<0.01），胶原亦有增高的趋势。

Phosphatide content in the silicosis group was also increased ( p < 0.01 ) . The contents of total lipid and phosphatide in the coal worker ' pneumoconiosis ( CWP ) of stage I were significantly higher than those in control group ( p < 0.05 ) .

由于平面BLMs和球形脂质体的实用性，这使得首次研究分隔两含水溶液的超薄（～6nm）类脂双层的电性质和传输现象成为可能。

With the availability of planar BLMs and spherical liposomes , it was possible to investigate electrical properties and transport phenomena across an ultrathin (~ 5nm ) bilayer lipid membrane separating two aqueous solutions .

磷脂酰甘油（Phosphatidylglycerol，简称PG）作为一种特殊的稀有磷脂，在对于新生儿呼吸窘迫综合征等肺部疾病的诊疗中具有一定的应用，不仅如此，磷脂酰甘油还是胡萝卜素类脂生物合成的中间产物。

As one special kind of rare phospholipids , Phosphatidylglycerol ( PG ) plays a certain role for the diagnosis and treatment of neonatal respiratory distress syndrome and other lung diseases . More than that , phosphatidylglycerol is the carotene lipid biosynthesis intermediates .

以金属支撑的双层类脂膜（s-BLM）为基本接受器元件，通过镶嵌磷酸盐离子载体开发了二价磷酸盐离子传感器。

The electrochemical devices for phosphate based on metal supported bilayer lipid membrane ( s-BLM ) was developed . It can be used as phosphate biosensor with the incorporation of phosphate ionophore into the lipid bilayer .