皮质酮
- corticosterone
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同时检测血浆皮质酮含量(CC)。
Plasma corticosterone ( CC ) concentration was determined by competitive protein-binding assay .
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结果:1.i.t注射吗啡组6小时后PHA-诱导的脾淋巴细胞增殖反应明显降低,血清皮质酮浓度明显升高,与生理盐水组相比差异显著(P<0.05)。
Results : 1 . PHA-induced splenic lymphocyte proliferation was significantly suppressed and the serum corticosterone level had elevated after morphine ( 40g / 50l ) injected in intrathecal .
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维生素E水平和应激对雏鸡血浆皮质酮浓度的影响
Effects of Supplemental Levels of Dietary Vitamin E and Immune Stress on Serum Concentrations of Corticosterone in Laying Hens
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脑不对称Balb/c小鼠血浆IL-1β、IL-6及皮质酮水平变化
The levels of Plasma IL-1 , IL-6 , corticosterone of Balb / c mice with lateralization
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目的观察转录因子Egr(Earlygrowthresponsefactor,早期生长反应因子)是否参与调控皮质酮处理的Leydig细胞中FasL启动子的活性。
Objective To observe whether Egr ( early growth response factor ) is involved in activation of FasL promotor in CORT-treated Leydig cells .
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皮质酮诱导大鼠Leydig细胞凋亡是一经caspase-3激活的过程
Caspase-3 activation is required for corticosterone-induced rat Leydig cell apoptosis
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皮质酮诱导的大鼠Leydig细胞凋亡中caspase-3活化途径的研究
The study on activation pathway of caspase-3 in corticosterone-induced Leydig cell apoptosis
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皮质酮快速抑制C6细胞摄取甘氨酸的信号转导
Signal transduction of rapid inhibitory effect of corticosterone on glycine uptake in C6 cells
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结果提示:海马内NA可能参与急性低氧应激引发血浆皮质酮分泌的调节活动。
The results above suggest that NA in hippocampus may participate in the regulation of the hypoxia-induced increase of plasma CS concentration in rats .
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皮质酮对原代培养海马神经元的毒性作用及NMDA受体亚基表达的改变
Neurotoxic effect of corticosterone on primary cultured hippocampal neurons and the change of NMDA receptor subunits expression
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结论:EF拮抗皮质酮诱导的大鼠肾上腺皮质过度凋亡是其拮抗糖皮质激素对HPA轴的抑制,保护肾上腺皮质功能的机制。
Conclusion : EF ' inhibition of adrenocortical cell apoptosis induced by corticosterone contributes to adrenal function recovery .
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甘草次酸的去氧皮质酮(DOC)样作用分析
Studies on the mechanism of the Desoxycorticosterone ( doc ) - like actions of glycyrrhetinic acid in the rat
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党参及其正丁醇提取物在小鼠的急性毒性和对血浆皮质酮、ACTH含量的影响
Acute Toxicity of Dangshen Its n-Butanol Extract Their Effect on the Plasma Level of Corticosterone ACTH in Mice
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结果:低氧暴露2h,24h后下丘脑的CRF分泌明显增加,血浆皮质酮水平显著升高,这种变化随着低氧程度的加深而增强。
Results : During acute hypoxia the secretion of CRF and level of plasma corticosterone rose significantly comparing with control .
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皮质酮快速抑制PC12细胞乙酰胆碱诱发电流影响及机制探讨
Rapid , non genomic inhibitory effect of corticosterone on acetylcholine
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阻断NMDA受体可增强皮质酮对海马脑源性神经营养因子表达的抑制:cAMP反应元件结合蛋白的作用
Blockade of NMDA receptor enhances corticosterone-induced downregulation of brain-derived neurotrophic factor gene expression in the rat hippocampus through cAMP response element binding protein pathway
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应用放免和ELISA方法测定烫伤大鼠血清皮质酮和细胞因子TNFα、IL1β的浓度变化。
The concentrations of corticosterone , TNF α and IL 1 β in the serum of scalded rats were detected with RIA and ELISA .
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结论:外源性褪黑素可改善皮质酮诱导的大鼠HPA轴及免疫功能受抑状态。
Conclusion : Exogenous melatonin can improve the inhibited state of HPA axis and immune function which induced by exogenous corticosterone of rat model .
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天敌应激下小鼠血浆皮质酮、巨噬细胞产生NO、IL-1β水平与脑不对称性
The Correlation of Brain Asymmetry to The Level of Plasma Corticosterone and NO , IL-1 β Produced by Macrophage in Balb / c Mice Under Predator Stress
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Ca~(2+)和CaN凋亡信号通路参与皮质酮诱导的Leydig细胞凋亡中FasL的表达
Involvement of Ca ~ ( 2 + ) and CaN signaling pathway in CORT-induced activation of fasl during apoptosis in rat leydig cell
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目的:观察归脾汤对慢性不可预见性模型大鼠血清皮质酮、雌激素(E2)水平的影响,初步探讨其防治抑郁症的可能机制。
Objective : To study the effect of Guipi Decoction on depression model rats serum cortisol and estradiol ( E2 ) and the mechanism is approached .
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小鼠15-20%Ⅲ0烧伤后血清皮质酮浓度显著升高,4h达到高峰,以后逐渐下降,到烧伤后24h仍未恢复正常。
Serum corticosterone level was markedly elevated and peaked at 4h postburn , it did not come back to the normal level at 24h .
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研究结果提示,长期大运动量递增负荷训练可使血清皮质酮水平升高,脑组织GR含量下降,减弱了对糖皮质激素的敏感性,使HPA轴的反馈作用降低。
It suggests that long-term incremental training load can increase the level of serum corticosterone , while the content of GR in brain cytosol decreases .
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补肾定喘汤对哮喘大鼠肺组织糖皮质激素受体及血浆皮质酮、ACTH的影响
Effect of Bushen Dingchuan Tang on Glucocorticoid Receptor of Pulmonary Tissue and Corticosterone and Adrenocorticotropic Hormone ( ACTH ) of Plasma in Asthmatic Rats
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皮质酮对C6细胞和SK-N-SH细胞作用的Km和Vmax不同。
The Km and Vmax of effect of B on glycine uptake in C6 cells were different from those in SK-N-SH cells .
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因此,我们观察了GR在低浓度皮质酮诱导巨噬细胞ERS中的作用。
Thus , we investigated the possible role of GR in the induction of ER stress in macrophages by low concentration of corticosterone .
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去氧皮质酮醋酸盐高血压大鼠模型中GTPCH-1和GFRP表达和活性的变化及其意义
GTPCH-1 and GFRP mRNA expression levels and activities variation in DOCA-salt hypertension rat
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这两种受体与皮质酮的亲和力不同,MR是高亲和力和低容量的GC受体系统,而GR为低亲和力和高容量的GC受体系统。
Both receptors have different affinity with corticosterone . MR is a high-affinity and low capacity of the GC receptor system , and GR for the low affinity and high capacity GC receptor system .
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HPLC法测定尿中脱氢皮质酮(A)与皮质酮(B)的比率及肾皮质微粒体酶对皮质酮的转化率评定肾11β-羟基类固醇脱氢酶活性。
The activity of 11 β - HSD was evaluated by measuring the ratio of 11-dehydro-corticosterone ( A ) and corticosterone ( B ) in urine and conversion rate of B to A in renal cortex microsome preparation was determined with HPLC .
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目的观察皮质酮(corticosterone,CORT)大鼠神经干细胞增殖分化的变化,探讨肾阳虚证与CORT大鼠神经干细胞增殖分化的联系。
Objective To explore the changes of differentiation and proliferation of neural stem cells in rats treated with corticosterone ( CORT ) .