疯草

苦马豆素（SW）是引起动物疯草中毒的主要毒性成分，研究表明它能直接作用于肿瘤细胞，表现出明显的抗肿瘤作用；

Swainsonine ( SW ) is the main poisonous composition of locoweed which can cause animals poisoning .

苦马豆素（Swainsonine，SW）属吲哚里西啶生物碱，是疯草（Locoweed）的主要有毒成分。

The indolizidine alkaloid swainsonine is the main toxic composition of Locoweed .

在我国，疯草广泛分布于西北、华北和西南的广大草原，危害面积达1100万hm2。

Locoweeds are mainly distributed on the vast rangeland , exceeding 11 million hectares , in northwest , north and southwest China .

苦马豆素（swainsonine，SW）是豆科黄芪属和棘豆属有毒植物（疯草）的主要有毒成分，其分子质量小，化学本质为多羟基吲哚里西啶生物碱。

Swainsonine ( SW ) is the primary toxicant in locoweeds within the genera Oxytropis and Astragalus , with a small molecular weight and chemically being indolizidine alkaloid .

本文主要对中国疯草内生真菌的分离与鉴定、产苦马豆素内生真菌的筛选、ITS-5.8Srdna序列及其遗传进化、遗传多态性、固体培养特性等方面进行研究。

This paper was main about the isolation and identification of fungal endophytes from locoweeds in China , determination of swainsonine-producing fungal endophytes , phylogenetic relationships based on ITS-5.8S rDNA sequences , genetic polymorphism and cultural characteristics on solid media of fungal endophytes . 1 .

这些病变与疯草中毒的典型病变完全不同。

These pathological changes are totally different from locoweed poisoning .

中国疯草防除与利用研究

Studies on the Prevention or Killing off and Utilization of China Locoweed

疯草灵缓释丸对绵羊黄花棘豆中毒的预防效果研究

Effect of " Fengcaoling Slow Release Pill " Preventing Oxytropis Poisoning in Sheep

我国西部草原疯草危害调查

Locoweed Harm Investigation in the West Grassland of China

动物棘豆属疯草中毒的临床症状

Clinical Symptoms of Toxicosis in Animals by Crazyweed

生长于美国西南部的紫色疯草，具有紫色、粉红色至白色的花。

Tufted locoweed of southwestern United States having purple or pink to white flowers .

我国主要疯草苦马豆素动态规律研究苦丁茶等10味中草药抑菌作用研究

Study on bacteriostasis of 10 kinds of chinese herbal medicines Such as broadleaf holly leaf

多年来，疯草严重威胁着当地畜牧业的发展，造成重大的经济损失。

It has been heavily endangering the local development of livestock husbandry and causing great economic loss .

疯草内生真菌的研究，将为我国动物疯草中毒研究开辟新的领域，为动物疯草中毒病的防治和疯草的利用提供新的科学依据。

The research about swainsonine-producing fungal endophyte will offer a new reference for controlling and using locoweed .

本试验的开展也为疯草内生细菌与苦马豆素关系的研究奠定基础。

It establishes the foundation for the research on the relationship between endophytic bacteria and SW in locoweed . 1 .

本试验为产苦马豆素内生真菌的液体发酵工艺研究提供依据，为进一步研究疯草内生真菌合成苦马豆素的途径、合成机理奠定了基础。

This study provides a basis for the study on the fermentation and the synthetic mechanism of swainsonine of endophytic fungi .

甘肃棘豆作为疯草中的一种，广泛分布于四川和甘肃等草场，对牧区畜牧业造成严重危害。

One of the locoweed , Oxytropis kansuensis Bunge , widely distributes in the pastoral pasture of northwestern Sichuan and Gansu province .

疯草是有世界性危害的一类重要有毒植物，也是中国第一大有毒植物。

Locoweed is a main poisonous plant in the world , and is also the most important toxic plant in grassland of China .

概述了疯草三类主要有毒成分：脂肪族硝基化合物、硒及硒化合物、疯草毒素（生物碱）。

This article summarized the three toxic constituent of locoweed : aliphatic nitro compound , selenium and selenide , locoweed toxin ( alkaloids ) .

疯草是指含有苦马豆素的豆科黄芪属和棘豆属有毒植物，动物疯草中毒病是危害草原畜牧业最严重的问题之一。

Locoweeds are toxic plants of the genera Astragalus and Oxytropis containing swainsonine . Locoism is one of the most widespread poisonous plant problems .

本试验对甘肃棘豆中内生细菌进行了初步分离、培养，为筛选疯草内生细菌中苦马豆素降解菌奠定基础。

This experiment isolated and cultured endophytic bacteria from Oxytropis kansuensis Bunge . which was as the foundation for screening of SW-degrading bacteria in locoweed . 3 .

苦马豆素降解菌的分离与鉴定通过富集驯化培养，从疯草生长环境中的土壤中分离出15株能够耐受高浓度苦马豆素的细菌。

Isolation and identification of swainsonine degrading bacterial strain 15 stains were found can resist to high concentration swainsonine from soil where locoweed grow , using traditional enrichment procedure .

本研究首次证实中国疯草中存在能够产生苦马豆素的内生真菌，将为从控制产苦马豆素内生真菌生长角度防治动物疯草中毒病提供依据。

It is the first document about swainsonine-producing fungal endophytes from locoweeds in China . The study offers a new possible avenue for dealing with locoism by controlling the endophytes instead of locoweed plants . 3 .

对内蒙古的疯草分布概况、牲畜疯草中毒机理、中毒的生态环境因素及其危害和疯草的开发利用进行了综述。

The locoweed distribution within Inner Mongolia , the locoweed poisoning mechanisms to livestock , the related ecological and environmental factors , damages caused and the prospects for developing and usage of the locoweeds were reviewed .

研究表明，疯草作为一种豆科植物，含有丰富的营养成分和矿物元素，如能将其合理的开发利用，不仅能控制疯草中毒，也能一定程度的解决饲草短缺问题。

Researches showed that locoweed is one of the Leguminosae plants , contains rich nutrition composition and mineral elements . If locoweed can be utilized reasonably , not only in the locoweed poisoning will be controled , but also the shortage of forage grass will be solved .

本研究建立的分析方法重现线性好，精确度高，结果准确可靠，可以满足疯草植物样品中苦马豆素含量的分析，为检测生物降解过程中苦马豆素含量变化奠定了基础。

The method is better reproducibility , rapid accurate , high degree of accuracy , and is useful to carry out qualitative and quantitative analyses of SW content in locoweed samples . This lays the foundation for detection of swainsonine changes in the progress of biodegradation . 3 .