甲氧基聚乙二醇
- 网络methoxy polyethylene glycol;mpeg;mpeg-spa
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甲氧基聚乙二醇(mPEG)是一种无免疫原性的兼性聚合分子,可以共价结合方式修饰各种蛋白质,减少其免疫原性,延长其在体内的停留时间,并用于制备通用血型。
The methoxy polyethylene glycol ( mPEG ) is a kind of amphoteric compound having no immunogenicity , which was used to modify various proteins covalently and to prepare versatile blood type .
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甲氧基聚乙二醇修饰脐血淋巴细胞抗原的实验研究
Methoxy polyethylene glycol modified lymphocytes antigens in cord blood
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甲氧基聚乙二醇遮蔽猕猴红细胞表面类人B抗原的研究
Chemical camouflage of like human B antigens on Rhesus monkey red blood cells with methoxy polyethylene glycol
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本论文首先利用甲氧基聚乙二醇(mPEG)改善壳聚糖的水溶性。
Firstly , water solubility of the chitosan was improved by methoxy poly ( ethylene glycol )( mPEG ) in this paper .
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根据分子结构设计原理,设计并以水为溶剂合成了一种以甲氧基聚乙二醇(MPEG)为接枝侧链的聚羧酸系高效减水剂(PC-C)。
A polycarboxylic superplasticizer ( PC-C ) grafted with MPEG side chains was designed according to principle of molecular structure and synthesized in water as solvent .
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采用端甲氧基聚乙二醇、马来酸酐、E-44环氧树脂合成了反应型环氧树脂乳化剂MeO-PEG-Ma-E-44,以相反转乳化技术制备E-44水性环氧树脂,研究了工艺条件对其性能的影响。
Reactive epoxy emulsifier MEO-PEG-Ma-E-44 was synthesized by MeO-PEG , Ma and E-44 epoxy resin . The waterborne E-44 epoxy resin was prepared by phase inversion technique .
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目的考察粒径和单甲氧基聚乙二醇(methoxypolyethyleneglycol,MePEG)相对分子质量对重组人肿瘤坏死因子(recombinanthumantumornecrosisfactor-,αrHuTNF-α)隐形纳米粒体外巨噬细胞吞噬和大鼠体内长循环的影响。
Aim To investigate the influence of particle size and methoxypolyethyleneglycol ( MePEG ) molecular weight on the in vitro macrophage uptake and in vivo long circulating of recombinant human tumor necrosis factor - α( rHuTNF - α) - loaded stealth nanoparticles in rats .
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将不同分子量的mPEG的羟基羧化后,与壳聚糖分子链上3位羟基发生酯化反应,制备出梳形可分散于水的甲氧基聚乙二醇接枝壳聚糖(CS-g-mPEG)。
MPEG with different molecular weights after carboxylated was occurred esterification reaction to the hydroxyl groups at C-3 on the chitosan backbone , and the comb-shaped methoxy poly ( ethylene glycol ) grafted chitosan ( CS-g-mPEG ) which can be dispersed in water was prepared .
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甲氧基聚乙二醇在肿瘤防治中的应用
Utilization of Methoxy Polyethylene Glycol on Prevention and Treatment of Tumor
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甲氧基聚乙二醇修饰人红细胞血型抗原的研究
Preliminary Study on Modification of Blood Group Antigens on Human Red Cells
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甲氧基聚乙二醇-磷脂酰乙醇胺的制备及其对脂质体的稳定作用
Preparation of Methoxy-poly ( ethylene glycol ) - phosphatidylethanolamine and Its Stabilizing Effect on Liposomes
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甲氧基聚乙二醇遮蔽红细胞表面抗原制备通用型血液的初步研究
Preliminary Study on Preparation of Universal Donor Blood by Camouflage of Red Blood Cell Surface Antigens with Methoxy Polyethylene Glycol
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将苯胺(An)与甲氧基聚乙二醇邻氨基苯基醚氧化共聚,制备了梳状接枝共聚物PAn-g-PEG。
The comb-shaped copolymers PAn-g-PEG were prepared by chemical oxidation copolymerization of aniline and methoxyl poly ( ethylene glycol ) o-aminophenyl ether .
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结果表明,大分子,特别是单甲氧基聚乙二醇的降低抗原性效果很好,但活力损失较大;
The results showed that the macromolecular modifiers are better than that of small molecular modifier acetic anhydride for reduction of antigenicity .
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聚乙二醇对猪凝血酶的化学修饰及其效果分析甲氧基聚乙二醇修饰红细胞解决自身免疫性疾病所致配血困难研究
Chemical Modification and Effect of PEG-5000 on Thrombin Modification of red blood cells by methoxy polyethylene glycol to solve the problem in compatibility test caused by autoimmune diseases