环酰胺

环酰胺杯芳烃聚硅氧烷固定相分离Grob试剂的研究

The separation of Grob mixtures by calixarene as chromatography phases stationary

本文设计合成了几种手性氮杂四元环酰胺类手性催化剂，研究了其在催化不对称Aldol反应中的应用，取得了较好的催化效果。

This paper designed and synthesized several chiral nitrogen-containing heterocyclic four-membered ring amide of chiral catalysts , studies its application in catalytic asymmetric Aldol reaction , and acquired better catalytic effect . 1 .

通过活性酯中间体合成大环酰胺的简便方法

Convenient synthesis of macrocyclic amides via active ester intermediates

叔丁基和脱叔丁基环酰胺杯[4]芳烃聚硅氧烷固定相的合成

The Synthesis of Calix [ 4 ] arene Polysiloxane Stationary Phases with Different Substitution

目的研究桥环黄皮酰胺差向异构体的结构。

AIM To study the structures of the epimerides of cycloclausenamide .

β晶型成核剂2,6-二（环戊基酰胺基）萘的合成

Synthesis of β - form Nucleating Agent 2,6-di ( cyclopentylcarbonylamine ) Naphthalene

环丙酰胺类化合物的卤化反应及其应用

Cyclopropanes Lactam Compounds of Halogenation Reaction and Its Application

N-（2,4-二氯苯基）环丙酰胺类化合物的合成与植物生长调节活性

Synthesis and Bioactivity of Chemical Plant Growth Regulators-N - ( 2,4-dichlorophenyl ) cyclopropane Carboxamide Compounds

大环多酰胺的合成进展

Synthesis development of large ring multi-amide

苯胺和苯酚与环酐的酰胺化及酯化反应

Amidation and Esterification of Cyclic Anhydrides with Aniline and Phenol

芳环取代桂皮酰胺类化合物的结构与抗惊活性的关系

Structure - anticonvulsant activity relationships of some cinnamamides of substituted aromatic ring

环1磷酰胺通过明显抑制骨形成而导致骨量减少，骨显微结构退化等典型骨质疏松特征的出现。

Cyclophosphamide causes osteopenia and microstructure degradation in rats , which are the typical feature of osteoporosis , by significantly inhibiting bone formation .

未完全环化的酰胺酸对聚酰亚胺的性能有重要影响，用电位滴定法可直接测定其含量。

The potentiometric titration technique was used to determine the content of residual amic acid in polyimide , which was synthesized by the two-step method .

方法：采用东莨菪碱及环己亚酰胺致小鼠学习记忆障碍模型，以水迷宫为学习记忆评价指标。

Method : The learning and memory tests were realized with a water maze on the learning and memory impact of mice induced by scopolamine and cycloheximide .

2007年至2009年，革兰氏阴性杆菌对抗菌药物的耐药性有逐年增长趋势，临床应用较多的头孢类、喹诺酮类抗生素及单环β内酰胺类抗生素氨曲南耐药性升高最为明显。

From 2007 to 2009 , antimicrobial drug resistance had a increasing trend year by year . The most obvious increase in drug resistance were cephalosporine 、 quinolones antibiotics and monocyclic β - lactam antibiotics-aztreonam , one of the main reasons was that they are widely used in clinical .

结论超广谱β-内酰胺酶是革兰阴性杆菌对第三代头孢菌素及单环β-内酰胺类抗生素耐药的最重要机制，应高度重视产ESBLs株的检测和药物敏感性试验。

Conclusion ESBLs palys an important role in the mechanism of Gram negative bacterium antibiotics resistance to Cephalosporin 's ( 3rd generation ) and monocycle beta lactam antibiotics . Both the detecting of ESBLs producing strains and the testing of antibiotic susceptibility should be highly emphasized .

大多数超广谱β-内酰胺酶由广谱酶TEM-1、2和SHV-1衍生而来，可以水解氧亚氨基头孢菌素类和单环β-内酰胺类抗生素。

Most ESBLs are derived from TEM-1 , 2 or SHV-1 enzymes and are capable of hydrolyzing oximino-cephalosporins . ESBLs are plasmid-mediated and can be inhibited by β - lactamase inhibitors .

高效液相色谱法直接分离单环β-内酰胺对映体

Direct Separation of Enantiomers of Monocylic β - Lactams by HPLC

单环β-内酰胺抗生素衍生物的合成研究

Studies on the syntheses of mono β - lactam antibiotic derivatives

含2-苯基-1,2,3-三唑基的单环β-内酰胺及噻唑啉酮衍生物的合成

Synthesis of New Monocyclic β - Lactams and 4-Thiazolidinones Containing 2-Phenyl-1,2,3-triazolyl

单环β-内酰胺新衍生物的合成和抑菌试验

Synthesis and antimicrobial test of some new monocyclic β - lactam derivatives

目的研究单环β-内酰胺类降脂药物的合成方法。

OBJECTIVE To study the synthesis of lipid-regulating drugs with monocyclic β - lactam .

在水溶液中单环β-内酰胺抗生素结构与活性关系的量子化学计算

Quantum Chemistry Study of Structure-activity Relationship of Monocycle β - lactam Antibiotics in Aqueous Solution

碱性条件下两种单环β-内酰胺抗生素开环反应机理的理论研究

Theoretical Study on the Ring-opening Reaction Mechanism of Two Monocycle - β - lactam Antibiotics under Basic Conditions

目的：合成新型的单环β-内酰胺类降脂药物，并研究其胆固醇吸收抑制的活性。

Aim : To study the synthesis and cholesterol-absorption inhibitory activity of novel lipid-regulating drugs with monocyclic β - lactam .

报道单环β-内酰胺抗生素重要中间体4-羟甲基-β-内酰胺（2）的新合成方法。

A new synthetic method for 4-hydroxymethyl-2-azetidinone ( 2 ), akey intermediate of monocyclic β - lactam antibiotics , was developed .

结果106株鲍氏不动杆菌对亚胺培南耐药率最低11.1%，对青霉素类、头孢菌素类和单环β-内酰胺类抗生素耐药率均较高，特别是氨曲南和哌拉西林；

Baumannii strains . RESULTS The antibiotic resistance test indicated that A. baumannii was most sensitive to imipenem , with 11.1 % of resistance rate , but highly resistant to penicillins , cephalosporins and helices β - lactam antibiotics , especially piperacillin and aztreonam .

N-烷基和N-芳基取代的苯甲酰胺羧酸环邻位的C-H键能够选择性的发生活化，被烯烃官能化后生成五元环的内酰胺。

In chapter two , ortho C-H bonds in the carboxylic acid ring of N-alkyl and N-aryl substituted benzamides was successfully and selectively activated and were functionalized by olefins to give five-membered lactam .

希夫碱型大环多胺锌配合物对α-吡啶甲酸对硝基苯酚酯催化水解的研究新型大环席夫碱和大环酰胺化合物的合成及表征

Kinetic investigation on hydrolysis of p-nitrophenyl picolinate catalyzed by zinc complex of Schiff base macrocyclic polyamine Study on the Synthesis and Characterization of New Macrocyclic Schiff Base and Macrocyclic Amide