书成之后因战乱频繁及印刷技术落后而流传不广且有窜乱，王叔和对其进行了首次整理。并在其随后撰写的《脉经》中收录了《伤寒杂病论》中的绝大部分内容。
But it was not spread widely after finished because the frequently war and the unadvanced printing technology . Wang Shuhe reorganized it for the first time , and included most of the content of it in his book Mai Jing .
王叔和