热原

方法：应用BET来检查盐酸雷尼替丁注射液中的热原，考察了盐酸雷尼替丁注射液对BET检查法的干扰行为。

Methods : Using BET to detect pyrogen in ranitidine hydrochloride injection , the interference of ranitidine hydrochloride injection to the process of BET was studied .

方法：采用家兔热原试验方法，对炭纤维增强壳聚糖复合棒材的24、48、72h三种浸提液样品进行检测。

Methods : Pyrogen test was performed in rabbits with extracted liquid of carbon fiber reinforced chitosan robs .

目的探讨银杏内酯B注射液的细菌内毒素检查方法，并与热原检查法比较。

Aim To establish a method using tachypleus amebocyte lysate ( TAL ) for testing the bacterial endotoxin in Ginkgolide B injection .

柴胡注射液对家兔内生致热原性发热及其脑脊液cAMP含量变化的效应

Effect of Bupleurum Chinense injection on endogenous pyrogen fever and change of cAMP concentration in cerebrospinal fluid in rabbits

不同浓度内生致热原的发热效应，脑脊液中cAMP的反应及热限的研究

Study on fever action , cAMP response in cerebrospinal fluid and hyperthermic ceiling by endogenous pyrogen in different concentration

在这组内源性热原中，研究得最清楚的是IL-1。

Of this group of endogenous pyrogens , most is known about interleukin-1 ( IL-1 ) .

两种清热方剂对家兔白细胞致热原性发热效应及脑脊液cAMP含量影响的比较

Comparison of the effect of two heat dissipating prescriptions on leucocytic pyrogen fever and cAMP concentration of cerebrospinal fluid in rabbits

采用鲎试剂法测血浆LPS浓度；鲎试剂在抗淋巴细胞免疫球蛋白热原检测中的应用

The LPS concentration of plasma was detected by limulus lysate test . Application of Limulus Amoebocyte Lysate Reagent to Estimating Pyrogen in Antilymphocyte Immunoglobulin

方法：通过电镜观察、SIS浸提液的pH值测定、皮肤致敏试验、热原试验等方法，对SIS的理化性能进行评价。

Methods : In vitro tests , including hypersensitive test , pH value , pyrogen test and electron-microscopy scanning , were employed to evaluate physicochemical properties of SIS .

（本品）为小瓶装，灭菌无热原，桔红色冻干粉沫，每小瓶含有10mg或50mg阿霉素盐酸盐与乳糖。

Sterile pyrogen-free , orange red , freeze-dried powder in vials containing10mg and50mg of doxorubicin hydrochloride with lactose .

目的探讨检测高纯度卵泡刺激素（FSH）产品中黄体生成素（LH），卵泡刺激素（FSH）的生物活性以及异常毒性、热原的方法。

Objective To determine the bioactivity of Luteinizing hormone ( LH )、 follicle stimulating hormone ( FSH ), abnormal toxicity and pyrogen of highly purified FSH product .

本文仅就IL-1β作为内生致热原可使体温调定点上移而引起调节性体温升高即发热这一作用作一综述。

This article summarizes the role of IL 1 β as endogenous pyrogen in elevating the thermoregulatory set point and causing a regulated rise in body temperature to induce fever .

对热原不合格的抗淋巴细胞免疫球蛋白（ALG）半制品再制条件进行了研究。

The reproductive conditions of anti-lymphocyte immunoglobulin ( ALG ) semi-finished product unqualified in pyrogen were studied .

目的：研究雷尼替丁氯化钠注射液细菌内毒素检查（BET）的干扰试验，建立用BET代替热原检查（PT）。

To study the interfere factors test of BET for ranitidine in sodium chloride Injection , to establish a method for bacterial endotoxin test ( BET ) instead of the pyrogen Test ( PT ) .

进行ICHA水泥溶血和热原的检测等多种方法对ICHA的生物相容性进行评价。

Hemolytic test and pyrogen test were performed .

目的比较普通级家兔与SPF级家兔在9个同工酶的异同，为分析不同基因背景的家兔对热原检测等实验的影响提供依据。

Objective To compare the disparity of nine isozymes in SPF and conventional rabbits , and to provide evidence for analyzing the influence of different genic background of rabbits on pyrogen test experiments .

根据参考文献和热原检查的兔剂量，我们认为透明质酸钠的细菌内毒素限值应定为5EU／ml以内。

According to the references and the pyrogen test data , we considered that the maximum value of bacterial endotoxin in sodium hyaluronate should be defined at 5EU / ml.

目的：研究SAGM红细胞保存液细菌内毒素检查法的可行性，以替代热原检查法。

OBJECTIVE : To study the feasibility of bacterial endotoxin test for SAGM erythrocyte preserve fluid as a substitute for pyrogen test .

采用灵敏度为0.5EU/ml的鲎试剂可进行细菌内毒素检查。【结论】细菌内毒素法适用于注射用奥扎格雷钠的热原检查。

【 Conclusion 】 The method of bacterial endotoxin is suitable for the pyrogen determination of ozagrel sodium .

对一批维生素B12注射液进行了质量检验，其澄明度、灌装量、热原、无菌检查结果均符合注射液的规定；

The quality of a batch of vitamin B 12 injection was checked . The results of check on transparency , capacity of perfusion , pyrogen and asepsis conformed with the standard of injection .

但是LPS同时表现出强烈的毒性反应（Shwartzman反应，热原性等），因此阻碍了它在临床上的应用，所以许多研究者一直致力于LPS的减毒研究。

However , LPS also shows strong toxic reaction ( Shwartzman reaction , pyrogenic reaction , etc ) that hinders its clinical application . Many researchers have been committed to the toxicity attenuation of LPS .

结果，检测1、2、5、10、20、50ml等6种规格90批次一次性注射器，热原均为阴性，合格率100%。

Results : Ninety batches of 6 specifications of 1,2,5,10 , 20 and 50 ml-disposable syringes were examined and the pyrogen was negative , with 100 % eligible rate .

通过小鼠和豚鼠毒性试验及热原性试验测定了BOMPC与偶联物的安全性。

The safety of the conjugate was confirmed in the toxic test of mice and guinea pigs .

mL-1。结论注射用头孢噻吩钠可用细菌内毒素检查法控制热原。

The maximum noninterference concentration of cefalotin sodium for injection is 1.0 mg · mL ~ ( - 1 ) Conclusion The bacterial endotoxin test method can be used for the controlling of cefalotin sodium for injection .

目的研究鲎试剂法与家兔法检测重组人干扰素α2b内毒素结果的相关性，并参照家兔热原试验的阈值量，来确定本制品质量标准中内毒素的限量标准。

Objective To study the relationship between the determination results of bacterial endotoxin by limulus test and rabbit test , and to determine the limit of bacterial endotoxin content in the product according to the threshold value defined in pyrogen test in rabbits .

结论对甘油氯化钠注射液进行2倍稀释以0.5EU/ml的鲎试剂检查其热原是可行的。

[ WTHZ ] Conclusion Compound glycerin injection in 2-fold dilution applied in 0.5 EU / ml limulus reagent in detection of its pyrogen is feasible .

结果：该药在0.5mg·ml-1浓度下不干扰内毒素试验。结论：该药采用内毒素检查法代替热原检查法，方法可行。

Result : Pirarubicin did not interfere with the endotoxin experiment in the concentration of 0 . 5 mg · ml-1 . Conclusion : It is feasible for endotoxin testing method instead of heat source testing method .

对清洁灭菌后相同规格的玻璃注射器检测90批次，检出热原阳性率平均为9.8%，1ml规格的注射器检出热原阳性率为25%。

Ninety batches of glass syringes of same specifications after cleaning and sterilization were also examined and the pyrogen positive rate was 9.8 % in average , with pyrogen positive rate of 1-ml syringes being 25 % .

方法本文用Ames试验、哺乳动物细胞染色体畸变试验、小鼠骨髓细胞微核试验、过敏试验和热原试验对H1用于肿瘤治疗的临床安全性进行了检测。

Methods In this study , clinical safety of H 1 in cancer therapy was examined using the Ames test , the mammalian cell chromosome aberration test , the micronucleus calculation of mouse bone marrow cells , the allergy test and the pyrogenicity test .

方法：复制家兔内毒素性和内生致热原性发热模型，观察QKL对两种发热模型的解热效应，以及对脑脊液cAMP含量的影响。

Method : To duplicate rabbits models of endotoxin ( ET ) fever and endogenous pyrogen ( EP ) fever were used to study of the antipyretic effect of QKL on the two kinds fever and cAMP content of cerebrospinal fluid ( CSF ) .