溴化异丙托品

溴化异丙托品对哮喘和COPD的支气管扩张作用

Effects of ipratropium bromide on bronchodilation in patients with asthma and COPD

目的：比较慢性阻塞性肺疾病（COPD）患者吸入200μg沙丁胺醇与吸入80μg溴化异丙托品进行支气管舒张试验结果的一致性。

To compare consistency of 200 μ g albuterol and 80 μ g Ipratropium Bromide as bronchodilator in pulmonary function test in COPD patients .

溴化异丙托品和沙丁胺醇合用对组胺、乙酰胆碱和KCl诱导的豚鼠气管条收缩的影响。

The inhibitory effect of ipratropium bromide with salbutamol on the contraction of guinea pig tracheal strips induced by histamine and KCl .

目的：比较溴化异丙托品（IPB）气雾剂与沙丁胺醇（SA）气雾剂分别使用及联合应用对哮喘和COPD患者的支扩作用。

Objective : To compare the effect of ipratropium bromide ( IPB ) with sulbutamol ( SA ), on bronchodilatation in patients with asthma and COPD .

目的观察吸入溴化异丙托品对大鼠慢性阻塞性肺疾病（COPD）模型气道和肺组织M受体的影响及其规律。

Objective To observe the effect of inhaled ipratropium bromide on airway and lung tissue muscarinic receptors ( MR ) in a rat model of chronic obstructive pulmonary disease ( COPD ) .

目的探寻定量评价慢性阻塞性肺疾病（COPD）患者呼吸困难的方法，并观察吸入M胆碱受体拮抗剂溴化异丙托品对其呼吸困难和运动能力的影响。

Objective To study the method of quantitative evaluation of dyspnea and to investigate the effects of M-receptor antagonist inhalation on dyspnea in patients with chronic obstructive pulmonary disease ( COPD ) during exercise .

结果：吸入可必特气雾剂在15,30minFEV1的改善情况高于单吸溴化异丙托品气雾剂（P<0.01）；

Our results showed that improvement in FEV 1 15 and 30 min after inhalation of Combivent was greater than those after inhalation of Atrovent ( P < 0.01 );

目的观察不同剂量的溴化异丙托品（IPB）短时及长期应用，对稳定期慢性阻塞性肺疾病（COPD）患者的肺功能及运动耐受性的影响。

Objective To compare the effects of varying doses of inhaled ipratropium bromide ( TPB ) and the impact on lung function and exercise tolerance using progressive cycle ergometry in patients with stable COPD .

溴化异丙托品联合沙丁胺醇雾化治疗儿童哮喘

Combined Salbutamol and Ipratropium Bromide by inhalation in the Treatment of Child Asthma

观察组患者吸入0.25g/L溴化异丙托品并行呼吸肌锻炼，疗程6个月，治疗前及治疗后6个月分别进行肺功能测定及生活质量评分。

Pulmonary function and QOL were evaluated remission before and 6 months after treatment .

溴化异丙托品组和茶碱组治疗前后β受体密度变化不显著。

There were no significant change of adrenoreceptor density after ipratropium bromide and theophylline therapy .

沙丁胺醇与溴化异丙托品即刻平喘的临床辨证疗效观察

Observation on clinically curative effects of salbutamol and ipratropium bromide on immediate remission of asthma

前言：目的：考察溴化异丙托品气雾吸入对婴儿喘息性疾病的疗效。

Objective : To observe the effect of ipratropinum bromide in treating the asthmatic disease in infants and preschool children .

目的：观察舒喘灵、溴化异丙托品联合吸入在儿童哮喘急性发作治疗中的疗效。

Purpose : to observe the effect of combined inhalation therapy of Salbutamol and Ipratropium Bromide on children with acute asthma episode .

目的探讨毒蕈碱乙酰胆碱能受体拮抗剂溴化异丙托品及阿托品对气道粘蛋白高分泌的作用。

Objective To investigate the effect of ipratropium bromide and atropine on airway mucin hypersecretion in the chronic bronchitis model of rats .

目的：观察β2受体激动剂硫酸特布他林和抗胆碱能药物溴化异丙托品联合雾化吸入治疗哮喘急性发作的作用。

Objective : To observe the effect of aerosol inhalation of β 2 receptor stimulant combined with anticholinergic in treating asthma attack .

溴化异丙托品和阿托品都显著减少气管上皮杯状细胞数目及粘蛋白的分泌。

Significant decrease in the number of tracheal epithelia goblet cells , secretion of mucin were observed in ipratropium bromide and atropine treated rats .

结论：长期应用β2受体激动剂会导致β受体下调，长期应用溴化异丙托品和茶碱对β受体无影响。

Conclusion : The adrenoreceptor will be down regulated after long β 2 agonist therapy . There were no changes of adrenoreceptor after ipratropium bromide and theophylline therapy .

结论采用氧启动雾化联合溴化异丙托品、盐酸氨溴索可以改善慢支急性加重期症状。

The difference ( P < 0.05 ) was significant between group A and B.Conclusion It is beneficial to treat recurrent chronic bronchitis with aggravation with oxygen startup atomization inhalation of ipratropium plus ambroxol .

方法：选取稳定期哮喘患者和健康志愿者为研究对象，对哮喘患者分别应用溴化异丙托品、β2受体激动剂、联合应用溴化异丙托品和β2受体激动剂、茶碱。

Method : 40 stable asthma patients and 10 health volunteers were involved into our study . The asthma patients were treated with ipratropium bromide ,β 2 agonist , ipratropium bromide and agonist , and theophylline randomly .

目的：体外比较单用及合用溴化异丙托品和沙丁胺醇对乙酰胆碱、组胺、氯化钾诱导的离体豚鼠气管条收缩作用的影响。

AIM : To study the effects of ipratropium bromide ( IB ) with and without salbutamol ( Sal ) on the contraction of guinea pig tracheal strips induced by acetylcholine , histamine and potassium chloride in vitro .