海马硬化

海马硬化的MRI诊断

MRI diagnosis of hippocampal sclerosis

头颅MRI检查4例发现左侧海马硬化，1例CT示右半球萎缩。

Cranial MRI showed left hippocampal sclerosis in 4 patients and CT brain scan showed right cerebral hemiatrophy in 1 case .

结果MR检查发现15例中海马硬化11例，4例未发现异常；

Results Among the 15 patients , 11 were found to have hippocampus sclerosis .

海马硬化MR质子波谱分析与MRI的对比研究

Studies on hippocampal sclerosis by ~ 1H MRS and MRI

结论原发性颞叶癫痫与海马硬化有关。MRI是检测海马硬化的首选方法。

Conclusion Hippocampal sclerosis was related to temporal lobe epilepsy , and magnetic resonance imaging was the first choice method to detect hippocampal sclerosis .

颞叶癫痫最常见且最主要的病理变化为海马硬化（hippocampussclerosis），包括神经细胞脱失，胶质增生和突触重组。

The main pathological change of TLE is hippocampus sclerosis , which includes neuron loss , gliosis and synapse reorganization .

海马硬化型癫痫颞叶的病理学及c-fos、c-jun表达研究

Investigation of pathology of neuron , expression of c-fos and c-jun in temporal lobe from temporal lobe epilepsy with hippocampal sclerosis

目的：研究氢质子核磁共振波谱成像在癫痫病灶定位诊断中及在海马硬化早期诊断中的应用价值，并探讨癫痫治疗后发作次数的减少与MRS的相应改变的关系。

Objective : To investigate the appliance value of hydrogen proton magnetic resonance spectroscopy ( 1H-MRS ) in the lateralization diagnosis of epilepsy and in the forepart diagnosis of hippocampi sclerosis .

SE3～6h后，大部分神经元坏死、丢失，胶质增生明显，形成典型的海马硬化；

After 3 ~ 6 hours of SE , most of neurons were disappeared and gliosis , then the typical hippocampal sclerosis was formed .

目的研究氢质子磁共振波谱成像（1H-MRS）在海马硬化早期诊断中的应用价值。

Objective To investigate the clinical value of ~ 1 hydrogen proton magnetic resonance spectroscopy ( ~ 1H-MRS ) in the diagnosis of hippocampal sclerosis ( HS ) .

研究背景：颞叶内侧癫痫（Mesialtemporallobeepilepsy，MTLE）是难治性癫痫的主要类型，其主要病理变化是海马硬化，但发病机制目前尚不完全清楚。

Background : Mesial Temporal Lobe Epilepsy ( MTLE ) is the main type of Intractable Epilepsy , and the main pathological change is hippocampus sclerosis . and the pathogenesis mechanism is still not entirely clear now .

结论HHE综合征是持续偏侧惊厥导致的偏瘫-癫癎综合征，海马硬化可能是反复癫癎所致海马的继发性损伤，而非癫癎的起源灶。

Conclusions HHE syndrome is recognized as hemiplegia-epilepsy syndrome after prolonged hemiconvulsion . The hippocampal sclerosis may be the consequence of repeated seizures , but not the cause .

颞叶癫痫：肿瘤性病变与海马硬化的手术治疗

Surgical treatment for temporal lobe epilepsy : mass lesions and hippocampus sclerosis

海马硬化的扩散张量成像参数值变化初步研究

Preliminary study on diffusion tensor imaging parameters in hippocampal sclerosis

结论：神经元凋亡部分参与了癫痫患者海马硬化的形成。

Conclusion : Neuron apoptosis is involved in hippocampus sclerosis of human epilepsy .

目的探讨原发性颞叶癫痫与海马硬化-MRI之间的关系。

Objective To investigate the relationship between temporal lobe epilepsy and hippocampal sclerosis .

门区神经元脱失仅在海马硬化组可见。

Hilus neuron lost in HS groups only .

弥散加权成像表观弥散系数值在儿童海马硬化术前评定中的应用

Application of diffusion-weighted imaging and apparent diffusion coefficient on children hippocampal sclerosis before operation

未发现海马硬化改变3例行前颞叶切除术。

Another 3 patients who were not found to have HS underwent temporal lobectomy .

在内科难治性颞叶癫？的患者中，海马硬化是最常见的神经病理学改变。

The hippocampal sclerosis is the most common neuropathologic finding in patients with medically refractory TLE .

海马硬化与颞叶癫痫的关系

Temporal Lobe Epilepsy and Hippocampus Sclerosis

复杂部分性癫痫与海马硬化

Complex Partial Epilepsy and Hippocampal Cirrhosis

额叶癫痫与海马硬化

Frontal epilepsy and hippocampal sclerosis

结论海马硬化是颞叶癫痫的主要原因，手术切除疗效满意。

Objective To study the surgery of temporal lobe epilepsy caused by mass lesions or hippocampus sclerosis .

目的：探讨神经元凋亡与颞叶癫痫患者海马硬化的关系。

Objective : To explore the relations between neuron apoptosis and hippocampus sclerosis of human temporal lobe epilepsy .

长时间癫痫发作后可出现脑内选择性的神经元凋亡坏死和海马硬化。

Long period epileptic seizure can show up elective apoptosis , necrosis of neuron and sclerosis of hippocampus .

患者均行单侧前颞叶手术，手术病理示不同程度海马硬化。

Unilateral anterior temporal lobectomy was performed in all patients and pathology showed different degrees of hippocampal sclerosis .

海马硬化与颞叶癫痫术前定位探讨（附12例报告）

A study of preoperative localization for hippocampus sclerosis in temporal lobe epilepsy ( 12 cases report ) .

海马硬化致耐药性颞叶内侧癫痫的耐药基因蛋白表达及意义

Expressions of drug-resistance related genes and the significance in sclerotic hippocampi from patients with drug-resistant mesial temporal lobe epilepsy

磁源性影像在海马硬化致癫灶定位中的应用结果脑磁图癫痫灶定位与术中皮质脑电图定位符合率100%。

Localization of epileptogenic foci caused by hippocampal sclerosis using MSI Results Epilepsy focus localization coincidence between MEG guided neuronavigation and ECoG was 100 % .