核输出信号
hé shū chū xìn hào
- 名nucleus export signal
核输出信号-
c-Abl属于非受体型酪氨酸磷酸激酶家族，是一个多结构域的复杂蛋白。含有核定位信号序列和核输出信号序列，可以在细胞核与细胞质之间穿梭。
C-Abl , a complex protein with multi-domains and functions , belongs to the non-receptor tyrosine kinase family , and it can shuttle between nucleus and cytoplasma depending on its nuclear localization signals and nuclear export signals .
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c-Abl借助其C端的3个核定位信号（NLS）和1个核输出信号（NES）完成细胞核-细胞质间的穿梭过程。
C-Abl can shuttle between the cytoplasm and the nucleus mediated by three NLSs ( nuclear localization signal ) and one NES ( nuclear export signal ) in its C-terminal domain .