核苷激酶
- 网络thymidine kinase;NDPK;nucleoside kinase
![核苷激酶](../cache/1190600.jpg)
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人体胸腺嘧啶核苷激酶不完全cDNA的分离、结构分析和表达
Isolation , Preliminary Characterization and Expression of a Near Full-length cDNA for Human Thymidine Kinase
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目的:研究转移抑制基因nm23表达产物二磷酸核苷激酶(NDPK)在人肺癌中的表达及意义。
Purpose To study expression and significance of the metastasis suppressor gene nm23 / NDPK in human lung carcinoma .
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分别于伤前、伤后6,12,24,48和72h处死动物,检测肠黏膜蛋白质含量、胸腺嘧啶核苷激酶活性、增生指数及PCNA表达。
Protein content , thy-midine kinase activity , proliferative index and PCNA expres-sion in the intestinal mucosa were analyzed at 0 , 6 , 12 , 24,48 , and 72 PBH respectively .
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目的研究单纯疱疹病毒胸腺嘧啶核苷激酶/更昔洛韦(Herpessimplexvirusthymidinekinase/gancyclovir,HSVtK/GCV)自杀基因系统对视网膜母细胞瘤(retinoblastoma,Rb)细胞的体外杀伤作用以及旁观者效应发生的机制。
Objective To investigate the killing effect of herpes simplex virus thymidine kinase / gancyclovir ( HSV tk / GCV ) suicide gene therapy system on retinoblastoma ( Rb ) cells and the mechanism of bystander effect .
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目的:了解二氢嘧啶脱氢酶(DPD)和胸腺嘧啶核苷激酶(TK)的研究现状和在临床肿瘤治疗中的意义。
OBJECTIVE : To provide the advances of the research in dihydropyrimidine dehydrogenase ( DPD ) and thymidine kinase ( TK ) and the significances of their applications in clinical tumor chemotherapy .
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目的建立一种灵敏、特异检测血清中二磷酸核苷激酶(NDPK-A)含量的酶联免疫吸附试验(ELISA)法和试剂盒,分析血清中的NDPK-A含量与血液病之间的关系。
Objective To establish a sensitive and a specific ELISA kit for detecting and analysing serum NDPK-A and to explore the relationship between serum NDPK-A content and hemopathy .
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广-9株的胸腺嘧啶核苷激酶(TK)基因既作为表达载体与痘苗病毒基因组体内重组的同源顺序,又作为重组病毒的筛选标记。
The thymidine kinase ( TK ) gene of Guang-9 in the vector provided not only the homologous sequences for in rive recombination with the vaccinia virus genome , but a so the selective marker for the virus recombinants .
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目的:构建含有单纯疱疹病毒胸腺嘧啶核苷激酶(HSV-tk)和增强绿色荧光蛋白(EGFP)的重组腺病毒载体,体外转染鼠内皮细胞,并检测其表达。
Objective : To construct a recombinant adenovirus vector carrying gene of herps simplex virus thymidine kinase ( HSV-tk ) and enhanced green fluorescent protein ( EGFP ), and detect its expression in rat endothelial cells .
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血清胸腺嘧啶核苷激酶的检测及临床意义
Clinical significance and development of thymidine kinase measurement in serum using anti-TK_1Ab
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胸腺嘧啶核苷激酶/丙氧鸟苷自杀基因系统旁观者效应机制的探讨
The mechanism of bystander effect in herpes simplex virus thymidine kinase / ganciclovir mediated gene therapy
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二磷酸核苷激酶在膀胱癌中的表达
Nucleoside diphosphate kinase in bladder carcinoma
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二氢嘧啶脱氢酶和胸腺嘧啶核苷激酶的研究进展
Advance in dihydropyrimidine dehydrogenase and thymidine kinase influencing on the clinical therapy of pyrimidine chemotherapy drugs
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目的了解核苷二磷酸激酶A亚基(NDPKA)能否提高顺铂的抗癌效果。
AIM To explore if nucleoside diphosphate kinase A ( NDPK-A ) can potentiate the antitumor action of cisplatin .
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中试规模生产重组人核苷二磷酸激酶A(rhNDPK-A)。
Production of recombinant human nucleoside diphosphate kinase A ( rhNDPK-A ) in pilot-scale .
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为探讨核苷二磷酸激酶/nm23(NDPK/nm23)在胆囊、胆管癌中的表达及临床意义,用免疫组化ABC法对41例胆囊癌、12例胆管癌NDPK/nm23表达进行了测定。
To explore the expression and clinical significance of DNPK / nm23 in gallbladder carcinomas and bile duct carcinomas , we examined 41 gallbladder carcinomas and 12 bile duct carcinomas with immunohistochemical ABC method .
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至少有7个miRNA家族参与NADPH-细胞色素P450还原酶、核苷二磷酸激酶、超氧歧化酶等过程和调控代谢及胁迫反应中必须蛋白质的形成,表明miRNA在这些过程中扮演极为重要的角色。
At least 7 of 11 miRNA families target NADPH-cytochrome P450 reductase , nucleoside diphosphate kinase , superoxide dismutase , etc. , proteins that are necessary in metabolism and stress response , suggesting that miRNAs play an important role in these processes .
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人重组核苷二磷酸激酶α亚基对MCF-7/S的影响
Effect of recombination human nucleoside diphosphate kinase on MCF-7 / S
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43个蛋白质中有4个表达量变化显著的被成功鉴定,分别为钴胺素生物合成蛋白、肽基脯氨酰顺反异构酶、核苷二磷酸激酶和N-乙酰-γ-谷氨酰磷酸脱氢酶。
Four proteins of cobalamin biosynthesis protein , N-acetyl-gamma-glutamyl-phosphate reductase , peptidyl prolyl cis-trans isomerase and nucleoside diphosphate kinase were successfully identified .