核染色质

SSCC分化较低，癌细胞较小，核染色质呈颗粒状，细胞形态上与SCLC有相似之处。

SSCC low differentiation , cancer cells small , granular nuclear chromatin , cell shape is similar with the SCLC .

视野中心部分的RBC含有几个Howell-Jolly小体或残余的核染色质内容物。

The RBC in the center of the field contains several Howell-Jolly bodies , or inclusions of nuclear chromatin remnants .

在这种情况下，人们有时笼统地称它们为核染色质。

In this condition , they are sometimes referred to collectively as the chromatin of the nucleus .

核心过程的表观遗传的产业包括DNA甲基化、组蛋白改性、核小体重建、核染色质动力学和互动子都存在。

Core processes of epigenetic inheritance include DNA methylation , histone modification , nucleosome remodeling , nuclear dynamics and chromatin interaction with non-coding RNAs .

精核染色质在卵核内分散延续的时间长达4h左右。

The dispersing of sperm chromatin in egg nucleus takes about 4 hours ;

凋亡的细胞表现为核染色质浓缩、边移，呈半月型、环状或不规则状，凋亡小体形成，电泳下见DNA梯状图谱。

The apoptosis was characterized by chromatin concentration and margination , in half-moon , loop , and irregular shapes , and apoptotic body formation , and DNA ladder formation by gel electrophoresis .

结果发现，形态学观察细胞皱缩，核染色质凝聚或者断裂；MTT实验显示药物抑制Hep-2细胞增殖，并且存在着时间依赖和一定范围内的剂量依赖关系。

The results showed that antineoplastic drug inhibited the proliferation of Hep-2 cells in a time and dose dependent manner in vitro .

核染色质凝集，可见凋亡小体。（3）药物血清作用24h对SGC-7901人胃癌细胞有明显的抑制作用，抑制率达47.78%：作用48h抑制更明显，抑制率达61.88%，抑制效应呈时间依赖性。

The serum contained Chinese herbs has evident inhibitory function to the human stomach cancer cell SGC-7901 . after 24h culture , the inhibiting rate is 47 . 78 % .

本实验用国产PEG作融合剂，进行CHO细胞与小鼠骨髓细胞融合和间期核染色质早凝聚诱导实验。

PEG was used as a fusogen in our experiment . The fusion of mitotic CHO cells with bone marrow cells of mice were performed and the induction of premature chromosome condensation of interphase nucleus was observed .

形态学观察结果显示，水泡性口炎病毒感染BHK-21细胞的形态变化具有较典型的凋亡特征，如细胞膜内陷、核染色质凝集边聚等；

The morphologic results showed that BHK-21 cells infected by VSV appeared peripheral condensation of chromatin , partition of cytoplasm and nucleus into membrane and so on .

扫描和透射电镜观察可见各实验组细胞表面微绒毛明显减少或消失、胞膜发泡、细胞固缩和核染色质浓缩边集，并出现凋亡小体，热疗+工SDN组的凋亡细胞数量更多。

With electron microscopy , great changes of cell apoptosis were observed , including microvilli disappearance or reduction , cell shrinkage , chromatin condensation or margination and the presence of " apoptosis bodies " .

1～10μg/ml丹参酮ⅡA作用72h后，肝癌细胞表现为细胞皱缩、核染色质浓缩、核碎裂、细胞出芽以及凋亡小体形成等凋亡特征性的形态学改变。

After treatment with 1 ~ 10 μ g / ml tanshinone ⅱ A for 72 h , BEL 7402 cell apoptosis with nuclear chromatin concentration and fragmentation as well as cell shrinkage and the formation of apoptotic bodies were observed .

形态学观察：倒置显微镜观察到实验组A-549肿瘤细胞体积变小、变圆，核染色质凝集，细胞间连接疏松，贴壁能力减弱。

Morphology survey inverted microscope . survey The A-549 human lung cancer cells with EPA showed cellular volume small and round , nuclear chromatin condensation , loose between the cells and adherent ability decrease under invert microscope .

结果证明，4次急性缺氧实验组均出现不同程度变化，主要表现为神经元微丝、微管模糊及胞核染色质凝集成大小不等的团块状的凋亡倾向，变化以存活7d、15d两组明显。

The animals of the experimental groups after four times acute repetitive hypoxia showed different extent changes as compare with control group . The main appearance was : the neuron tended to apoptosis , microfilaments and microtubules were obscure and chromatin in nucleus collected into different sized dumplings .

几种动物间期核染色质的电镜研究

Study on interphase chromatin in some animal species by TEM

习惯性流产患者丈夫精子核染色质状态评价

The Evaluation of the Sperm Chromatin Status from Spouses of Women with Spontaneous Abortion

荧光显微镜下核染色质凝聚成点状结构；

Under the fluorescence microscopy , condensed chromatin stained by DAPI formed dotted chromatin .

精核染色质在极核里分散的时间大约需用1小时。

The scatt-ering of the sperm chromatin in the polar nucleus takes about 1 hour .

核染色质很细，核质电子密度低，大多含一个核仁。

The nucleus contained fine homogeneous dispersed chromatin and , mostly , a single nucleolus .

细胞融合和间期核染色质早凝聚的分析

The Analysis of the Fusion of Cells and the Induction Premature Chromosome Condensation of Interphase Nucleus

平滑肌细胞出现核染色质浓缩与边聚，核周腔扩大；

Vascular smooth muscle cell : the chromatin was condensed and marginated and perinuclear space was dilated ;

结果：①光镜下，HE染色药物组细胞，由梭形细胞变为圆形或卵圆形，核染色质密集。

Results : ① LM : the shape of the cells changed into round or oval shape .

透射电镜下见嗅球摘除术后嗅觉神经元出现胞质浓缩、胞核染色质边聚等细胞凋亡的特征性超微结构改变。

Ultrastructural data of olfactory mucosa showed that the feature of apoptotic neurons was chromatin condensation and cell shrinkage .

爪蟾卵无细胞系统中核的自组装和组装核染色质纤维的研究

A Study of Nuclear Self-assembly and the Chromation Fibre of the Assembled Nuclei in the Cell-free System of Xenopus Eggs

结果表明：双歧杆菌经荷瘤鼠腹腔注射后能诱导多量大肠癌细胞凋亡，凋亡早期的细胞主要表现为核染色质浓缩边聚；

The results showed that this bacteria could induce apoptosis of tumor cells when injected into the peritoneum of tumor-bearing mouses .

结果（1）高频电流的高温作用致边缘组织收缩、细胞变形，体积变小，核染色质浓染；

Results The periphery of the tissue shrink of circumference , the deformation of cells , the body shorten , chromatin dens ;

核染色质有皱缩，但无核溶解现象。（2）透射电镜观察可见细胞核固缩以及染色质分布欠均匀等细胞凋亡的特征性变化；

Under transmission electron microscopy , apoptotic cells exhibited typical morphological changes , including irregular shape of nucleus , chromatin condensation , etc ;

凋亡细胞主要表现为胞浆膜起泡，核染色质浓缩，形成新月状核或膜包裹核染色质的凋亡小体；

The apoptotic cells mainly showed cytoplasmic membrane blebbing , chromatin condensation and fragmentation , and crescentic nuclear and membrane bound apoptotic bodies formation .

其形态结构发生了一系列变化，主要包括：核染色质浓缩、线粒体的发达与融合、顶体形成和胞质的减少。

A series of changes occurred in morphology and structure , including chromatin condensation , development and fusion of mitochondria , acrosome formation and cytoplasmic diminution .

结果透射电镜观察发现凋亡细胞典型的形态学变化&核染色质凝集边集，凋亡小体形成等。

Results Characteristic morphologic changes of apoptotic cells were observed under transmission electron microscope with chromatin condensation and margination as well as formation of apoptotic bodies .