无菌动物

实验动物按其微生物、寄生虫控制程度，可划分为四个等级，即普通动物、清洁动物、无特定病原体动物（SPF动物）和无菌动物。

According to the disparities of carrying microorganisms and parasites , laboratory animals can be classified into four grades : normal animal , clean animal , specific pathogen free animal ( SPF animal ) and sterile animal .

接种特定菌株后的无菌动物成为悉生动物，将它们与普通动物进行体内代谢作用的比较研究，是考察肠道菌群在体内对药物进行代谢的主要方法之一。

In the present paper , the pharmacokinetic study of Huangqin-Tang in rats , and the relation between intestinal bacteria and metabolism in vivo of Huangqin-Tang decoction were performanced .

需要补充的是，普通动物的肠道壁比无菌动物厚，这可能是由肠道细菌引起轻度炎症所致。

In addition , the intestinal wall of the normal animal is much thicker than that of the germ-free animals , probably because of low level inflammation caused by the bacterial flora .

【方法与结果】向家兔腹腔注射1%酪蛋白350ml，构建兔腹腔无菌性炎症动物模型。

[ Meathod and Results ] The rabbits ' abdominal cavities were injected by 350 ml 1 % casein to establish peritoneal sterile inflammation animals ' models .