异位表达

溃疡性结肠炎异位表达PS2蛋白的检测及意义

Study on ectopic expression of PS_2 protein in the tissue of ulcerative colitis

β-catenin的异位表达与COX-2的过表达没有相关性。

The ectopic expression of β - catenin was not associated with the COX-2 overexpression .

统计结果显示，正常喉粘膜组织与喉癌组织的p一catetrin表达之间差异有显著性（尸0.01）。2.喉癌中p一catenin膜表达与异位表达之间呈负相关性（p0.05）。

There was a statistical difference of p-catenin expression between normal tissue and laryngeal cancer ( P0.01 ) . 2 .

9例无功能性胰岛细胞瘤TSH、FSH和LH的异位表达

Expression of tsh , fsh and LH in nonsecreting islet cell tumors

大豆中一个含BURP结构域蛋白基因的克隆，异位表达与亚细胞定位

Molecular Cloning , Ectopic Expression and Subcellular Localization of a Soybean BURP Domain-containing Protein Gene

培养的A-T细胞经pTO-ATM病毒载体转导后，用免疫组织化学方法证明了ATM在这些细胞的异位表达。

Ectopic expression of ATM was demonstrated by immunohistochemistry in cultured A T cells after transduction of the pTO ATM viral vector .

结果表明，在HBV编码的蛋白中，HBx的异位表达能够强烈地促进pri-miR-192启动子的活性。

The results showed that over-expression of HBx , but not other proteins , could strongly enhance the activity of pri-miR-192 promoter .

结论：鼻咽癌中E-cadherin的增强表达可降低bcl-2基因的表达，β-catenin异位表达可能在调节bcl-2基因的表达中起重要的作用。

Conclusion : Enhanced expression of E cadherin may reduce bcl 2 expression in NPC , and the ectopic expression of β catenin may play an important role in the regulation of bcl 2 expression .

E钙粘蛋白（E&Cadhrine，E-cad）是一类主要介导同型细胞之间粘附的钙依赖性跨膜糖蛋白，它表达的减弱、消失或异位表达与许多肿瘤转移的发生率呈正相关。

E-cadherin ( E-cad ) is one of the most important adhesive molecules responsible for the calcium-dependent intra-cellular adhesion mechanism , The aberrant expression of E-cad possesses a close relationship with invasion and metastasis of tumor .

结果正常大肠粘膜βcatenin蛋白表达位于细胞膜，大肠腺瘤和大肠腺瘤癌变组织的βcatenin细胞膜表达有不同程度的缺失，而细胞浆和细胞核异位表达明显增加。

Results β catenin expression was detected on the cell membrane in normal colorectal mucosa . Reduced membrane expression , cytoplasmic and nuclear expression were detected in the colorectal adenoma and adenoma with canceration .

另外，异位表达REP1导致形成不对称的过度分化的内稃细胞，改变了花的对称性。

Furthermore , ectopic expression of REP1 caused the asymmetrical overdifferentiation of the palea cells , altering their floral asymmetry .

与异位表达SUB1A-1的转基因水稻一样，组成性表达SUB1A的拟南芥表现出对GA的不敏感和多脱落酸的超敏感。

As in rice transgenic plants that ectopically express SUB1A-1 , Arabidopsis transgenic plants that constitutively express SUB1A displayed GA insensitivity and abscisic acid hypersensitivity .

结论（1）癫痫发作后急性期海马NPY表达增多及颗粒细胞层出现异位表达，与癫痫发作有关；

Conclusions ( 1 ) The expression of NPY positive cells was increased after seizures , and aberrant expression of NPY was seen in the granular cell layer of hippocampus , which seemed to be related to seizures .

通过异位表达外源的4个转录因子能够诱导体细胞重编程为诱导多能干细胞（iPSCs），但是诱导iPS产生的效率很低。

Somatic cells can be reprogrammed to induced pluripotent stem cells ( iPSCs ) by ectopic expression of defined transcriptional factors . The efficiency of this process , however , is extremely low .

目的研究BCSC-1基因异位表达对人鼻咽癌细胞CNE-2L2恶性生物学行为的影响。

Objective To study effects of ectopic expression of BCSC-1 gene on the malignant activities of human nasopharyngeal carcinoma cell CNE-2L2 .

直肠腺癌组织中VEGF-C及其受体VEGF-R3异位表达在淋巴管内皮细胞上，而在血管中未见表达，差异有显著性（P<0.01）。

That the malposition of VEGF-C and VEGF-R3 in the endothelium of lymphatic vessels in the adenocarcinoma tissue of rectum , but not in the endothelium of the blood vessels shows great diversity between them ( P < 0.01 ) .

结论GSK-3β表达下调可引起β-连环素的异位表达，继而活化下游靶基因C-jun，使C-jun蛋白表达增高，β-连环素可能通过Wnt信号通路参与MCA引起的大鼠气道上皮鳞状化生。

Conclusion The down-regulation of GSK-3 β causes the ectopic expression of β - catenin , then activates the downstream oncogene C-jun and raises the expression of C-jun protein . β - catenin may be involved in squamous metaplasia of airway epithelium induced by MCA through Wnt pathway .

β-catenin细胞核异位表达是散发性结直肠腺癌发生发展过程中的早期改变。

β - catenin nuclear expression in sporadic colorectal adenocarcinomas is an early alteration .

组织因子/凝血因子Ⅶ在大肠癌中的异位表达及其临床意义

Ectopic expression and clinical significance of tissue factor / coagulation factor ⅶ complex in colorectal cancer

然而，我们的研究发现，在没有颗粒酶的参与下，异位表达的穿孔素本身就有可能诱导凋亡。

However , in absence of granzymes in our allotropic expression system , perforin seemed to induce apoptotic cell death by itself .

结直肠癌β-catenin异位表达率为63.1%，细胞膜表达缺失率为70.8%。

The abnormal expression rate of β - catenin was 63.1 % and the reduced membrane expression rate was 70.8 % in colorectal carcinoma .

亲代谢性谷氨酸盐受体异位表达在人黑色素瘤发病机制中可能是重要的因素，而且针对这种通路的治疗可能是一种有效的治疗。

The ectopic expression of metabotropic glutamate receptors may be important in the pathogenesis of human melanoma , and targeting this pathway may be an effective therapy .

异位表达的策略暗示了穿孔素潜在的凋亡诱导活性，而靶细胞的凋亡有助于机体的免疫监视和免疫防御，也提示穿孔素可以作为潜在的药物用于治疗。

The allotropic expression strategy implies the potential apoptosis-inducing ability of perforin which may benefit immune surveillance and defense , and might also be adopted for therapeutic purpose .

同工酶研究发现，雄蕊位心皮的酯酶酶带和过氧化物酶酶带与本身雌蕊酶带一致，充分表明该雄性不育确系心皮异位表达引起。

From the study of isoenzyme , the band of esterase and POD of carpelloid organs on stamens'position were consistent with themselves pistils ' , the results shows that the male sterile line is caused by ectopic expression of carpel .

基因芯片技术筛选子宫内膜异位症表达差异基因及COX-2、VEGF的作用研究

Screening of Differentially Expressed Genes of Endometriosis by cDNA Microarray Technique and the Investigation of COX-2 、 VEGF

STZ诱导小鼠糖尿病模型中胸腺异位基因表达的研究

Studies of STZ-induced promiscuous gene expression in thymus of IDDM mice

目的探讨自身免疫调节因子（autoimmuneregulator，Aire）对胸腺髓质上皮细胞（Medullarythymicepithelialcells，mTECs）异位基因表达的影响。

Objective : To investigate the effects of autoimmune regulator ( Aire ) to promiscuous genes expression in medullary thymic epithelial cells ( mTECs ) .

Aire对胸腺髓质上皮细胞异位基因表达影响的研究

Study of promiscuous genes expression in mTECs influenced by Aire

PR在子宫肌层的内膜异位阳性表达率为86.6%，卵巢内膜异位为20.0%，5例输卵管内膜异位均表达阳性。

The positive rate of PR expression in ectopic endometrium of myometrium and ovary was 86.6 % and 20.0 % , respectively ; while there was positive expression in all of the cases of uterine tube .

结论（1）Aire对mTECs异位基因表达有明显的促进作用；

Conclusion : ( 1 ) There is obvious promotion of Aire to promiscuous genes expression in mTECs .