帕罗西汀

建立了HPLC法测定盐酸帕罗西汀中R-异构体的含量。

A HPLC method for determination of R-isomer in paroxetine hydrochloride was established .

目的研究帕罗西汀治疗社交焦虑症（SAD）的疗效、副反应。

Objective To study the efficacy and side effects of Paroxetine in treatment of social anxiety disorder .

盐酸帕罗西汀中R-异构体的HPLC测定

Determination of R-Isomer in Paroxetine Hydrochloride by HPLC

目的评价帕罗西汀对肠易激综合征（Irritablebowelsyndrome，IBS）的症状疗效及抑郁量表评分影响。

Objective To evaluate the efficacy of the paroxetine for irritable bowel syndrome ( IBS ) with depression .

T.帕罗西汀替换三环类抗抑郁剂治疗抑郁症对照研究

A comparative study of paroxetine versus tricyclic antidepressants for depression High Efficient Three Ring Type Gear Reducer

帕罗西汀对Sprague-Dawley大鼠睡眠呼吸暂停的影响

Effect of Paroxetine on Sleep Apneas in Sprague-Dawley Rats

帕罗西汀治疗6周前后，检测两组患者的血清皮质醇、细胞因子IL-2、IL-6、TNF-α的浓度。

Cortisol , IL-2 , IL-6 and TNF - α were detected in all patients before and after a 6-week treatment with Paroxetine .

方法：收集国内医药杂志上公开发表的6篇帕罗西汀与阿米替林对照治疗抑郁症研究的文章，作Meta分析。

Methods : Meta-analysis was made to comparatively study on Par and Ami by six literature published from internal medical journals .

结论：常规治疗合用帕罗西汀，既能显著改善FD症状，又能有效控制抑郁焦虑障碍。

CONCLUTION : Conventional therapy plus paroxetine can improve the symptoms of FD and control the depression and anxiety disorder effectively .

它还企图误导美国食品药品监督管理局（fda），不让后者掌握到底有多少青少年在研究试验中因服用帕罗西汀而做出伤害自身的行为或企图自杀。

It also attempted to mislead the food and Drug Administration about how many adolescents had injured or attempted to kill themselves after taking Paxil in research trials .

平均有效剂量：舍曲林30.8mg，氟西汀与帕罗西汀均接近于20mg。

The mean daily therapeutic doses of sertralin , paroxetine and fluoxetine were 30 mg , 20 mg and 20 mg , respectively .

目的通过对卒中后抑郁（PSD）患者帕罗西汀治疗前后P300的研究，探讨PSD患者认知损害的发生机制。

Objective To evaluate the event related potential ( ERP or P 300 ) in post-stroke depression ( PSD ) with paroxetine and investigate the possible mechanism of cognitive dysfunction in PSD .

抗抑郁药帕罗西汀对应激所致大鼠海马组织学和行为学改变的影响及与CREB相关信号通路的关系

Effects of Antidepressant Paroxetine on the Changes of Histology and Behavior in Rats Hippocampus Induced by Stress and Their Relationships with CREB-related Signal Cascades

与治疗窗较窄的CYP2D6底物合用时，应注意帕罗西汀和氟西汀的剂量调整。

For fluoxetine and paroxetine , dosage cutting is needed in case of coadministration with CYP2D6 substrates .

目的：观察帕罗西汀对心理应激大鼠下丘脑CFos表达的影响，以揭示帕罗西汀治疗心理应激引起焦虑的分子作用机制。

AIM : To study the effects of paroxetine on the psychological stress induced by c-fos gene expression in the rat hypothalamus paraventricular nucleus ( PVN ) and to explore the molecular mechanism of effects of paroxetine on the stress related anxiety disorders .

目的：采用多中心、随机对照的临床研究方案，研究电针头穴加耳针治疗地震后创伤应激障碍（PTSD）与西药帕罗西汀疗效之间的差异，为PTSD的临床防治提供新方法。

Objective : To study the therapeutic effects of scalp electric acupuncture combining with auricular acupuncture in treating posttraumatic stress disorder ( PTSD ) through Randomized Control Trial ( RCT ) .

盐酸帕罗西汀作为SSRIs的代表药物之一，因其起效快、疗效确切，已成为当前畅销的抗抑郁药之一。

Paroxetine hydrochloride as the representative medicine of SSRIs , which is the best-selling antidepressants for its fast and clear effect at present .

结论抑郁症患者甲状腺激素水平降低，帕罗西汀对FT4水平有影响，抑郁症患者ATA与躯体焦虑相关。

Conclusion The serum levels of thyroid hormones in patients with depression is lower . Paroxetine may influence serum FT4 levels and there is correlation of ATA levels with anxiousness of patients .

目的：了解选择性5羟色胺再摄取抑制剂（SSRIs）氟西汀、舍曲林、帕罗西汀的不良反应特点，增强对5羟色胺（5HT）综合征的认识。

AIM : To study the characteristic of adverse reactions of SSRIs such as fluoxetine , sertraline , paroxetine and to enhance the realization of the serotonin syndrome .

目的探讨焦点解决短期治疗（SFBT）合用帕罗西汀（赛乐特）对社交恐惧症的临床疗效。

Objective : To evaluate the effect of solution-focused brief therapy ( SFBT ) combined with paroxetine in treatment of social phobia .

在常规治疗的基础上随机予IBS患者选择性5鄄羟色胺再摄取抑制剂（SSRI）类抗抑郁药治疗，20例患者使用盐酸帕罗西汀，16例患者使用盐酸氟西汀，疗程均为12周。

On the basis of routine treatment , selective serotonin reuptake inhibitor ( SSRI ) antidepressants were randomly given to IBS patients for 12 weeks , among them , 20 received paroxetine hydrochloride , 16 received fluoxetine hydrochloride .

结果：联用帕罗西汀12周后，PANSS总分、阴性症状因子分及情感迟钝、情感退缩、情感交流障碍、被动/淡漠及社交退缩因子分均比治疗前显著降低。

Results : After 12 weeks of treatments , the total scores of PANSS and scores of all the factors , including negative factor , emotional blunting , emotional withdrawal , emotional exchange disorder , passive / apathy , and social withdrawal factor were significantly decreased .

方法多中心合作研究，180例符合抑郁症诊断标准患者，给予帕罗西汀治疗6月，采用HAMD-17、HAMA和SF-36分别在治疗前、治疗3月和6月评价。

Methods It is a multi-center collaborative clinical trial and 180 cases who met the diagnostic criteria of major depression are involved . The patients are treated with paroxetine for 6 months and assessed with HAMD , HAMA and SF-36 at baseline , 3-month and 6-month after treatment .

国产帕罗西汀与丙米嗪治疗抑郁症对照研究

Control study of paroxetine and imipramine in the treatment of depression

帕罗西汀治疗抑郁症疗效和药物不良反应的双盲对照研究

A randomized double-blind amitriptyline-controlled study of paroxetine treatment for major depression

曲唑酮1周起效，无严重副反应，疗效与帕罗西汀相当。

Trazodone was as effective as paroxetine without severe side effects .

艾司西酞普兰与帕罗西汀治疗惊恐障碍对照研究

A Control Study on Efficacy Escitalopram and Paroxetine for Panic Disorder

利培酮联合小剂量帕罗西汀治疗精神分裂症阴性症状临床观察

Combination of risperidone and small-dose paroxetine in negative symptoms of schizophrenia

帕罗西汀对功能性消化不良患者生活质量的影响

Effect of paroxetine on life quality of patients with functional dyspepsia

帕罗西汀对多发性硬化伴抑郁状态及神经功能康复的影响

Effect of paroxetine on multiple sclerosis with depression and neurological functional rehabilitation