定位候选克隆

目的收集一遗传性单纯少毛症家系，通过定位候选克隆技术，识别该病的致病基因，以阐明遗传性单纯少毛症的发病机制。

Objective To collect pedigree of hereditary hypotrichosis simplex . To identify the gene for hereditary hypotrichosis simplex by positional cloning or positional candidate cloning technique and clarify the pathogenesis of hereditary hypotrichosis simplex more clearly .

致病基因的定位候选克隆精神分裂症的候选基因研究

Positional candidate strategy for disease gene identification Candidate Gene Study for Schizophrenia

近年来，国内外学者对高度近视的遗传学研究进一步深入，已应用全基因组扫描和候选基因筛查、连锁分析等技术进行病理性近视相关基因定位和候选基因克隆定位工作。

For the past few years , with the further of genetics research aimed to pathological myopia , the scholars utilize the techniques such as genome scan 、 candidate gene screening 、 linkage analysis to locate the related gene of pathological myopia and the candidate gene clone .