安乃近

安乃近的热分解过程和热分解非等温动力学

Studies on Thermal Decomposition Process and the Non-Isothermal Decomposition Kinetics for Analginum

RP&HPLC法测定兔血浆中安乃近及其活性代谢物的浓度

Determination of Analginum and Its Main Active Metabolites in Rabbit Plasma by RP-HPLC

C组用金刚烷胺+安乃近治疗；

Amantadine and analgin were together applied in Group C ;

目的：建立专属性强的HPLC法测定安乃近片含量。

Objective : To establish an HPLC method for determining the content of Metamizole Sodium Tablets .

结论：安乃近溶液鼻粘膜吸收机制为被动扩散，吸收符合一级动力学，吸收速度常数K为0.02219min－1。

CONCLUSION : The mechanism of analgin nasal absorption is passive diffusion , following first order kinetics , the absorption rate constant is 0.022 19 min - 1 .

经该方法处理后的安乃近废水，其COD去除率为99.2%，脱色率达100%，达到了医药行业的废水二级排放标准。

Experimental results that , for analgin wastewater , the removal ratio of COD was 99.2 % and decolourisation rate was 100 % by using the process . The analgin wastewater treated can reach the second effluent standard of medical wastewater .

2.5mg/kg的FM镇痛率即达82.7%，明显强于双氯芬酸钠（65.4%）和安乃近（58.7%）。

The pain-inhibition rate of FM ( 2.5 mg / kg ) reached 87.7 % , which was obviously higher than that of diclofenac sodium ( 65.4 % ) and analgin ( 58.7 % ) .

以Ce4+安乃近罗丹明6G的化学发光反应以及安乃近在胶束中的自氧化化学发光反应为例，介绍了BPCL微弱发光测量仪与流动注射装置相结合测定痕量药物的微弱化学发光分析方法。

One is based on the chemiluminescence reaction of Ce (ⅳ) analgin rhodamine 6G and the other is based on the auto oxidation of analgin in micellar medium . An ultra weak chemiluminescence analyzer has been coupled to flow injection device for the determinations .

复方安乃近片引起儿童暴发性肝衰竭

Fulminant hepatic failure caused by compound analgin tablets in a child

安乃近片剂及其注射液的红外光谱鉴别

Identification of metamizole sodium tablets and its injection by IR spectrum

安乃近的流动注射分光光度法分析

Study on the method for determination of analgin using flow injection spectrophotometry

安乃近注射液每次10mg/kg，肌注。

Intramuscular injections of Analgin were given 10mg / kg each time .

结论细菌内毒素检查法适用于安乃近。

Conclusion The method is suitable for the detection of this injection .

局部刺激性较弱，与安乃近针相似；

Local stimulatory function is weak , similar to analgin ;

电位法快速测定复方制剂中安乃近含量

Determination of Metamizole in the Compound Solution by Potentiometric Method

目的：研究安乃近片剂的热特征。

Objective : To study the thermal characteristics of metamizole sodium tablets .

安乃近过敏所致变态反应性疾病三例探讨

Autoimmune Disease due to Analgin & Report of 3 cases

多中心平行对照比较布洛芬与安乃近的疗效和安全性

Multicenter parallel comparison of the efficacy and tolerability of ibuprofen vs metamizole

目的探讨安乃近细菌内毒素检查方法的可行性。

Objective To investigate the feasibility of bacterial endotoxin test for analgin injection .

磷酸盐浓度越低越不利于安乃近溶液的稳定；

The lower the phosphate concentration , the less stable the analgin solution ;

安乃近滴鼻剂与药物的鼻腔吸收

Analgin Nose Drops and Nasal Drug Absorption

安乃近测定新方法的研究

Study on the New Determination of Analginum

酸性染料比色法测定复方安乃近微型灌肠剂中盐酸氯丙嗪含量的研究

Determination of Content of Chlorpromazine Hydrochloride in Compound Metamizole Sodium Microenema by Acid dye Colorimetric Method

目的：解决高浓度安乃近共存情况下，盐酸氯丙嗪的含量测定。

OBJECTIVES : To determine the content of chlorpromazine hydrochloride in the samples with high concentration of analginum .

水中安乃近高级氧化法去除及其产物的毒性评价

Degradation of dipyrone in water by advanced oxidation processes and evaluation of the toxicity for the degradation products

结论：本方法可用于复方安乃近片的快速分析，方法简便、准确。

Conclusion : This method is successfully used to rapid assay compound metamizole sodium tablets with simple and accurate .

运用褶合光谱仪检查安乃近原料中4－N－去甲基安乃近的限量，方法简便，结果准确，所得结果与法定方法一致。

This method is simple and accurate and the results obtained is identical with that of the legal method .

此外，对药物的鼻粘膜纤毛毒性也进行了研究。结果：安乃近、对乙酰氨基酚鼻腔吸收良好，有望开发为鼻腔给药制剂；

Results : Analgin and acetaminophen were absorbed through nasal route easily and suitable to be developed as nasal preparations ;

方法：以溴麝香草酚蓝为反离子，甲苯为萃取溶剂，建立了复方安乃近微型灌肠剂中盐酸氯丙嗪的含量测定方法。

METHODS : The extraction spectrophotometry with bromothymol blue as counter ion had been established for the measurement of chlorpromazine hydrochloride .

本文采用乳化法制备了空载明胶微球和包载安乃近、乳酸环丙沙星、乳酸诺氟沙星的兽用明胶微球。

Using the emulsification method , microspheres containing metamizole sodium , ciprofloxacin lactate and norfloxacin lactate were prepared , with gelatin as polymer coatingmaterials .