奈瑟

四川省B群脑膜炎奈瑟菌脉冲场凝胶电泳分型分析

Molecular typing of Neisseria meningitidis serogroup B strains with pulsed field gel electrophoresis in Sichuan

脑膜炎双球菌性关节炎脑膜炎球菌性视神经炎辽宁省健康人群C群脑膜炎奈瑟菌血清杀菌力检测

Testing of antibodies against Serogroup C Neisseria Meningitidis by Serum Bactericidal Assay in Healthy Population , Liaoning Province

产青霉素酶淋病奈瑟菌的DNA检测

DNA detection of penicillinase-producing Neisseria gonorrhoeae

淋病奈瑟菌孔蛋白B原核重组质粒的构建、表达与蛋白鉴定

Construction of Neisseria gonorrhoeae Porin B Plasmid Recombinant and Its Expression in E.coli and Identification of Fusion Protein

淋病奈瑟菌PCR检测的临床应用研究

Clinical Application of PCR Assay for Detection of Neisseria gonorrhoeae

实时荧光定量PCR法检测淋病奈瑟菌感染的效果

Real-time fluorescence quantitative polymerase chain reaction for detection of Neisseria gonorrhoeae infection

实时荧光PCR法检测正常人脑膜炎奈瑟菌

Detection of Neisseria meningitides in Healthy Population by Real Time Quantitative PCR

PCR对可疑慢性淋病病人淋病奈瑟菌的检测

Detection of Neisseria gonorrhea by PCR in the suspicious patients with chronic gonorrhea

结论淋病奈瑟菌孔蛋白PⅠB原核表达质粒构建正确。

Conclusion A plasmid recombinant encoding porin B of Neisseria gonorrhoeae has been successfully constructed and expressed in E. coli .

潍坊市健康人群A、C群脑膜炎奈瑟菌抗体水平调查

Investigation on Antibody Against Epidemic Cerebrospinal Meningitis ( Serogroup A and Serogroup C ) Among the Healthy Population in Weifang

淋病奈瑟菌隐蔽性质粒的克隆及PCR的建立与应用

Cloning of the cryptic plasmid from Neisseria gonorrhoeae and the clinical application with PCR

脑膜炎奈瑟菌A群荚膜多糖与B群外膜蛋白复合物偶联物的制备和免疫原性

Preparation and the immunogenicity of the conjugate made from group A capsular polysaccharide and group B outer membrane protein complex of Neisseria meningitidis

采用PCR方法检测的脑脊液标本和/或菌株培养呈阳性，均证实主要由A群脑膜炎奈瑟菌引起。

Cerebrospinal fluid specimens tested by PCR and / or culture positive have confirmed the large predominance of Neisseria meningitidis serogroup A.

扩增siaD（C）基因确认C血清群脑膜炎奈瑟菌。

To confirm C serogroup Neisseria meningitidis , siaD ( C ) gene was detected by PCR method .

太原铁路职业人群流行性脑脊髓膜炎A群、C群奈瑟菌IgG抗体水平分析

Statistical analysis and classification of epidemic cerebrospinal meningitis group A and C Neisseria meningitides IgG levels in the railway occupational population in Taiyuan

目的以蛋白质组学研究为基础，分析2003～2005年间我国流脑暴发流行期间C群脑膜炎奈瑟菌菌株分布特征。

Objective This study was conducted to analyze the distribution characteristics of the serogroup C Neisseria meningitidis strains isolated during the epidemic outbreaks between 2003 and 2005 in China .

方法将C群奈瑟脑膜炎球菌多糖经溴化氰活化后通过己二酰肼衍生后制备出适宜的多糖衍生物。

Methods Feasible polysaccharide derivative was obtained by combining the serogroup C neisseria meningococcal polysaccharide which was activated by cyanogen bromide ( CNBr ) with 1,6-adipic acid dihydrazide ( ADH ) .

PI为主要外膜蛋白，占淋病奈瑟菌外膜总重量的60%以上，具有较高的稳定性和免疫原性。

The PI with higher stability and immunogenicity is a main outer membrane protein , occupied 60 % outer membrane protein total weight .

鉴别29E群、X群和Z群脑膜炎奈瑟菌聚合酶链反应方法的建立及应用

Establishment and application of PCR assay for identification of Neisseria meningitidis serogroup 29E , X , and Z

目的：构建淋病奈瑟菌孔蛋白PIA（PorinIA）基因的真核表达系统，为淋病DNA疫苗的研究提供材料。

Objective : To construct an eukaryotic expression system carrying the Neisseria gonorrhoeae Porin IA ( PIA ) gene .

淋病奈瑟菌mtrR基因启动子区的IR区碱基缺失与其耐药性关系的研究

Study of Relationship Between IR Gene Deletion in The mtrR Gene Promoter and Antibiotic Resistance of Neisseria Gonorrhoeae

方法：对261例CP患者进行症状评分及对其EPS标本进行常规培养、淋病奈瑟菌的特殊培养和支原体、衣原体测定。

Methods : 261 patients with CP were evaluated for symptoms and their EPS was incubated for examination of Neisseria gonorrhoeae , mycoplasma , and chlamydia .

目的克隆和分析淋病奈瑟菌孔蛋白（porinⅠB，PⅠB）的基因序列并表达相应的蛋白质，为淋病奈瑟菌感染的检测和基因工程疫苗的研究与开发建立基础。

Objective To clone porin B ( P ⅰ B ) sequences of Neisseria gonorrhoeae and analyze the protein expression as basis of research in detection , prophylactic and therapeutic vaccine against the pathogen infection .

方法采用琼脂稀释法测定13种抗菌药物对35株淋病奈瑟球菌的MICs；

Methods MICs of 13 antimicrobial agents to 35 Neisseria gonorrhoeae were tested by agar dilution procedure .

目的：了解细胞壁缺陷对淋病奈瑟菌隐蔽性质粒B基因（cppB）的影响。

Objective : To understand the influence of cell wall deficiency on the cryptic plasmid B ( cppB ) gene of Neisseria gonorrhoeae Methods : The N.

淋病奈瑟菌pIB基因的克隆、原核表达及其表达产物免疫学鉴定

Construction and prokaryotic expression of Neisseria gonorrhoeae pIB gene and immunological identification of expressed product

结果207株淋病奈瑟菌血清学分型检测显示94株（45.4%）属于WI群；

Results The data of the serological classification of 207 isolates showed : 94 isolates ( 45.4 % ) were W I groups ?

无锡地区淋病奈瑟菌TEM-1基因分子流行病学研究

A molecular-epidemiologic study on TEM-1 genes of Neisseria gonorrhoeae in Wuxi area

细胞壁缺陷型淋病奈瑟菌cppB基因的检测

Determination of cryptic plasmid B gene in cell wall deficiency of Neisseria gonorrhoeae

结论：淋球菌染色体mtrR启动子区域的IR区基因突变会引起mtrC基因转录增加，进而提高奈瑟淋球菌的耐药性。

Conclusions : Mutation in IR domain of NG mtrR promoter region may enhance transcription of mtrC gene and further elevate the drug resistance of NGs .