多西环素

C组口服多西环素（品名：强力霉素）外用硫磺炉甘石洗剂。

Group C by oral doxycycline and topical sulfur calamine lotions .

耐四环素的Uu和Mh株对多西环素、米诺环素、交沙霉素以及氧氟沙星存在交叉耐药性。

The tetracycline-resistant Uu or Mh showed cross resistance to doxycycline , minocycline , josamycin and ofloxacin .

HPLC测定盐酸多西环素可溶性粉含量

Determination Content of Doxycycline Hyclate Powder by HPLC

目的：采用超声心动图观察大鼠心肌梗死（MI）模型中外源性基质金属蛋白酶抑制剂多西环素对左心室功能的保护作用。

Objective : Protection of doxycycline ( extragenous inhibitor of matrix metalloproteinases ) on cardiac function was observed following myocardial infarction in rats by echocardiography .

方法：对60例寻常痤疮随机分为二组治疗，A组（30例）用盐酸多西环素胶囊治疗，B组（30例）用二甲胺四环素胶囊治疗，治疗时间均为21天；

Methods : 60 cases of acne vulgaris were randomly divided into two groups : Group A ( 30 cases ) were treated with doxycycline hydrochloride capsules for three weeks ; Group B were treated with minocycline capsules for three weeks ;

通过对电极缓冲体系、pH值、乙腈添加浓度、N-甲基吗啡啉添加浓度及温度、电压的优化选择，用毛细管电泳方法分离土霉素、金霉素、多西环素、四环素、氯霉素5种抗生素。

Five antibiotics compounds , tetracycline , oxytetracycline , doxycycline , chlortetracycline and chloramphenicol , were successfully separated by capillary electrophoresis . Effects of buffer , pH , various organic additives , temperature and voltage were investigated in this paper .

目的：观察盐酸多西环素对心肌梗死后心肌基质金属蛋白酶-9（MMP-9）的影响及对心室重构的作用机制。

Objective : To observe the effects of doxycycline on matrix metalloproteinases-9 ( MMP-9 ) and ventricular remodeling ( VRM ) in rats after myocardial infarction and discuss its mechanisms .

方法骨关节炎患者的单层软骨细胞和滑膜细胞均以白细胞介素1β、转化生长因子β1、肿瘤坏死因子α、双氯芬酸钠、多西环素和地塞米松分别处理72h。

Methods The chondrocyte and synoviocyte monolayer was stimulated with IL 1 β, TGF β 1 , TNF α, diclofenac acid , dexamethasone and doxycycline individually for 72 hours .

目的探讨多西环素对体外培养的人结膜上皮细胞细胞黏附分子1（ICAM1，CD54）、人类白细胞抗原DR（HLADR）、白细胞介素1β（IL1β）表达及凋亡的影响。

Objective To evaluate the effects of doxycycline on the regulation of intercellular adhesion molecule-1 ( ICAM-1 , CD54 ), interleukin-1 β ( IL-1 β), human leukocyte antigen DR ( HLA-DR ) and apoptosis in human conjunctival epithelial cells .

结论9名健康受试者分别静脉滴注盐酸多西环素，药-时曲线符合二房室模型，在100～300mg剂量范围内药物体内过程呈线性动力学特征。

Conclusion The serum concentration-time curve of doxycycline hydrochloride fit two-compartment model . The pharmaceutical characteristics of doxycycline hydrochloride in human body were linear in the range of 100mg ~ 300mg .

20mg多西环素片剂联合局部外用0.75%甲硝唑洗剂治疗酒渣鼻疗效的随机、双盲、安慰剂对照试验

A randomized , double - blind , placebo - cont - rolled trial of the combined effect of doxycycline hyclate 20 - mg tablets and metronidazole 0.75 % topical lotion in the treatment of rosacea

结论：开封地区非淋菌性患者支原体感染以Uu为主，在9种常用治疗支原体的抗菌药物中以多西环素、米诺环素和克拉霉素耐药性较低，罗红霉素的耐药性最高。

CONCLUSIONS : The patients with non-gonococcus urethritis were chiefly caused by Uu infection in Kaifeng area . Of the 9 commonly used antibacterials against mycoplasma , doxycycline , minocycline and clarithromycin showed the lowest drug resistance , while roxithromycin showed the highest drug resistance .

方法对本组7例的临床特点结合文献进行了归纳分析，并观察了多西环素、克拉霉素和罗红霉素对Reiter病的疗效。

Methods Inductive analysis of the clinical characteristic was carried out on 7 patients with incomplete Reiter 's disease , with other papers being referred to . And the therapeutic effects of doxycycline , clarithromycin and roxithromycin on the disorder were observed .

目的评价多西环素缓释给药系统（SRDDS）移植于引导组织再生（GTR）屏障膜下的骨缺损中时，对口腔细菌定植屏障膜的影响。

Objective To evaluate the effects of a novel local sustained-release drug delivery system ( SRDDS ) for doxycycline on bacterial colonization of the barrier membranes when it is implanted into osseous defect treated by guided tissue regeneration ( GTR ) .

目的研究广谱基质金属蛋白酶抑制剂多西环素对卒中易感型自发性高血压大鼠（SHR-SP）脑血管系统基质金属蛋白酶的作用，探讨多西环素对脑卒中的发病率及病死率的影响。

Objective To investigate the effects of doxycycline on cerebral matrix metalloproteinases ( MMPs ) in stroke-prone spontaneously hypertensive rats ( SHR-SP ) , and its contribution to stroke incidence , mortality rate and stroke volume in SHR-SP.

多西环素缓释系统对细菌定植牙周引导组织再生术屏障膜的影响

Effects of local delivery doxycycline on bacterial colonization of barrier membranes

结论盐酸多西环素是治疗痤疮的有效药物。

Conclusion Doxycycline hydrochloride is an effective drug in treating acne .

多西环素联合维胺酯治疗痤疮疗效观察

Study on the effect of oral viaminate and doxycycline in acne

莫西沙星与多西环素治疗女性非淋菌性宫颈、尿道炎的疗效比较

Comparison of therapeutic effects between moxifloxacin and doxycycline on non-gonococcal genito-urethritis

多西环素减轻小鼠内毒素性急性肺损伤的作用及机制研究

Protection effect and mechanism of Doxycycline on lipopolysaccharide-induced acute lung in mice

盐酸多西环素胶囊治疗寻常痤疮的临床观察

Clinical observation of acne vulgaris treated with doxycycline hydrochloride capsules

多西环素联合氟尿嘧啶抑制结直肠癌肝转移的实验研究

The Study of Doxycycline United Fluorouracil Inhibiting Liver Metastasis in Colorectal Carcinoma

并利用该体系对盐酸四环素以及盐酸多西环素进行实验研究。

And using the system for tetracycline hydrochloride and doxycycline .

2种多西环素注射液在健康猪体内的药动学比较

Comparision of Pharmacokinetics of Two Different Doxycycline Injections in Pigs

多西环素肠溶微粒胶囊与片剂的人体生物等效性

Bioequivalence of doxycycline enteric-coated microsomes capsule and its tablet in healthy volunteers

四环素和多西环素对人牙周韧带细胞生物学活性的影响

Biological Effects of Tetracycline and Doxycycline on Cultured Human Periodontal Ligament Cells

头孢曲松钠、米诺环素、多西环素则是有效的驱梅替代药物。

Ceftriaxone sodium , minocycline , doxycycline are valid alternative medicines for syphilis .

盐酸多西环素脂质体凝胶剂的制备与评价

Preparation and Evaluation of Doxycycline Hydrochloride Liposomes Gel

步骤：按盐酸多西环素的含量测定项下进行。

Procedure - Proceed as directed for Procedure in the Assay under Doxycycline Hyclate .

目的：观察口服维胺酯胶囊和多西环素治疗寻常痤疮的临床疗效。

Objective To investigate the clinical effect of oral viaminate and doxycycline in acne .