咪达唑仑

B组，椎管内麻醉复合静脉推注咪达唑仑镇静；

The Group B undergoing CSEA with intravenous bolus of midazolam for sedation ;

HPLC法同时测定人血浆中咪达唑仑和阿曲库铵的浓度

HPLC determination of midazolam and atracurium in human plasma

结论腹腔注射咪达唑仑50mg/kg（连续3d）可短暂加重东莨菪碱致大鼠认知功能障碍。

Conclusion Midazolam can aggravate transiently the cognitive dysfunction induced by scopolamine in rats .

HPLC测定人血浆中咪达唑仑含量

Determination of Plasma Concentration of Midazolam by HPLC

静脉注射咪达唑仑与芬太尼用于ICU机械通气患者镇静的临床观察

Sedative effect of midazolam and fentanyl on ventilated patients in ICU

结论：AAI、BIS均可定量、准确地反映咪达唑仑的镇静效果。

Conclusion : Both AAI and BIS can assess midazolam-induced sedation quantitatively and accurately .

P组病人均存在内隐记忆，两联合用药组病人内隐记忆均消失。结论：小剂量异丙酚和咪达唑仑联合镇静可以消除外显记忆和内隐记忆。

Implicit memory was spared in Group P. However , it was eliminated in Group PM 1 and Group PM 2 . Conclusions : Explicit memory and implicit memory can be eliminated by the small dose of propofol in combination with midazolam .

提取小鼠肝P450酶，建立咪达唑仑的体外代谢模型。

Incubation of " Creation " A model of midazolam metabolism in vitro was developed with rat liver microsomal ( P450 ) incubation .

目的比较咪达唑仑（midazolam）和艾司唑仑（estazolam）治疗高血压患者长期失眠的疗效和安全性。

Objective To compare the safety and efficacy of midazolam and estazolam in hypertensive patients with chronic insomnia .

方法选择60例ASAⅠ～Ⅱ级拟行妇科手术病人，年龄20～45岁，随机分为咪达唑仑组（M组）和对照组（C组）。

Methods 60 patients ( 20 ~ 45 yr of age , ASA physical status I or II ) undergoing elective gynecological surgery were randomly divided into midazolam ( M ) and control ( C ) groups .

结果所有患者在给咪达唑仑负荷剂量后，RS从1级下降至3～5级，达到很好的镇静要求，且在维持量下能保持良好的镇静水平，有效率100%；

Results RS of all patients decreased from grade 1 to grades 3 - 5 after administration of the loading dose . All patients got a calm state and kept it under the maintenance dose .

结论咪达唑仑具有良好的镇静效果和用药可操控性，并可适当改善机械通气的效果，且用药安全，可用于ARDS患者的长期镇静。

Midazolam could also boost the effectiveness of mechanical breathing . Conclusion Midazolam is a better alternative for the patients with ARDS because of its outstanding sedative efficacy , yarage , and safety .

目的观察异丙酚、咪达唑仑及吡咯烷二硫代氨基甲酸酯（PDTC）对大鼠体外循环（CPB）后急性肺损伤（ALI）的影响。

Objective To examine the effects of propofol , midazolam and pyrrolidine dithiocarbamate ( PDTC ) on acute lung injury ( ALI ) induced by normothermic cardiopulmonary bypass ( CPB ) .

所有病人经异丙酚或异丙酚联合咪达唑仑镇静15min后，让病人听录音带即内隐记忆刺激。

15 min after induction of sedation the patients were subjected to listening to an audiotape ( implicit memory priming ) .

1/2IC50的异丙酚与咪达唑仑合用时的IC50数值点落在理论上的相加等效线的95%可信区间的左下方。

The IC 50 values of midazolam combined with 1 / 2 IC 50 propofol located under the 95 % confidence limits of theoretical additive line .

目的探讨咪达唑仑靶控输注（TCI）系统用于臂丛神经阻滞患者清醒镇静的可行性及中国人咪达唑仑清醒镇静靶控血药浓度。

Objective To confirm the feasibility of target-controlled infusion of midazolam on conscious sedation for patients undergoing brachial plexus nerve block and the needed target-controlled blood concentration .

在相同的镇静程度下，DEX比咪达唑仑更有利丁维持呼吸道通畅，可能更适用于该类手术的镇静。

Compared with midazolam , DEX might show more advantages in maintaining the unobstructed of the respiratory tract , and be more suitable for sedation in lower limbs surgery .

观察组（60例）给予小剂量咪达唑仑（约1mg）和丙泊酚诱导麻醉，对照组（60例）给予0.9%的氯化钠溶液和丙泊酚。

Observation group ( 60 patients ) low dose midazolam ( approximately lmg ) and propofol induction of anesthesia , the control group ( 60 cases ) to give 0.9 % sodium chloride solution and propofol .

方法20例ASAⅠ～Ⅱ级拟行下腹盆腔手术的女性患者，以椎管内麻醉复合靶控输注咪达唑仑镇静，设定咪达唑仑靶控血浆浓度为100ng/ml。

Methods Twenty female patients scheduled for selective lower abdominal or pelvic surgery under combined spinal and epidural anesthesia were enrolled in this study . They use combined spinal and epidural anesthesia with target controlled infusion of midazolam sedation . Midazolam plasma concentration was set at 100ng / ml.

静脉注射咪达唑仑0.05mg/kg，芬太尼4μg/kg，丙泊酚2mg/kg，维库溴铵0.1mg/kg诱导行气管插管。

Induced tracheal intubation by intravenous injected midazolam 0.05 mg / kg , fentanyl 4 μ g / kg , propofol 2 mg / kg , vecuronium bromide 0.1 mg / kg .

结果咪达唑仑TCI系统的偏离性老年组（7.9%）略低于年轻组（11.6%），精确度两组都为20.0%，均在临床应用可接收范围内。

Results The bias ( median performance error ) of the TCI system of midazolam was 7.9 % in the elderly group and 11.6 % in young groups . The precision ( median absolute performance error ) was 20.0 % in both groups . They were clinically acceptable .

结论咪达唑仑0.06mg/kg和丙泊酚1.0mg/kg作为首次剂量用于结肠镜检查，检查中适时追加丙泊酚镇静深度，镇静效果满意且安全。

Conclusions Fundamental sedation with intravenous midazolam at 0.06 mg / kg and propofol at 1.0 mg / kg can be applied for colonoscopy . A bonus of 20 ~ 30 mg propofol , if necessary , during the procedure is effective and safe .

1例德巴金与咪达唑仑配伍禁忌的报告

Report of a case of incompatibility between sodium valproate and midazolam

咪达唑仑对全麻术中知晓显性记忆的影响

The effect of midazolam on dominance memory in general intravenous anesthesia

鼻腔滴入咪达唑仑治疗儿童急性惊厥的疗效观察

Clinical effectiveness of intranasal midazolam administration in acute children seizures control

咪达唑仑和芬太尼用于腰硬联合麻醉镇静的临床观察

Effect of midazolam and fentanyl on combined spinal-epidural anesthesia and sedation

方法以芬太尼和咪达唑仑诱导，静脉泵注异丙酚维持。

Methods Anesthetic induced with intravenous administration of fentanil and midazolam .

咪达唑仑对交感神经元N-型钙通道电流的影响

Effects of midazolam on N-type calcium currents of rat sympathetic neurons

咪达唑仑对大鼠杏仁核点燃抑制作用的研究

The Study of Inhibition of Midazolam on Amygdala Kindling in Rats

咪达唑仑治疗儿童癫痫持续状态及惊厥频繁发作的临床研究

Treatment of midazolam to continuous status epilepticus and frequent convulsion seizures