用弗利斯重排、甲基化、双分子还原，1,2-二醇消除及去甲基反应得到己烯雌酚。
Phenol was used as a primary material . The diethylstilbestrol was obtained by the Fries Rearrangement , methylation , bimolecular reduction , elimination of 1 , 2-diol and demethylation .
双分子还原