内向整流
- inward rectifier
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AngⅡ受体对内向整流性钾流的影响
The Effects of Angiotensin ⅱ Receptors on Inward Rectifier Potassium Current
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结论:高胆固醇血症可改变血管功能,并影响某些内向整流和ATP敏感钾通道亚型的基因表达。
CONCLUSION : Hypercholesterolemia altered the vascular functions and regulated gene expression levels of specific inward rectifier and ATP-sensitive potassium channel subtypes .
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蛋白激酶C对内向整流钾离子通道的调节机制
Modulation mechanism of PKC upon inwardly rectifying potassium channels
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小鼠心肌细胞中的G蛋白门控内向整流钾通道及其功能
Expression and Function of G Protein Gated Inwardly Rectifying K Channels in Mouse Ventricular Cardiomyocytes
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碘化N-正丁基氟哌啶醇(F2)对心肌细胞内向整流钾通道的影响
Effects of N-n-butyl Haloperidol Iodide ( F_2 ) on Inwardly Rectifying Potassium Channels of Cardiac Myocytes
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ATP敏感钾通道(KATP)是一类较广泛分布的内向整流钾通道。
ATP sensitive K + channels ( K ATP ) are a widely distributed group of inwardly rectifier K + channels .
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腺苷拮抗ISO对豚鼠心室肌细胞动作电位及内向整流钾通道作用机制的探讨
Study of Mechanism of Adenosine Antagonized Isoproterenol on Action Potentials and Inward Rectifier Potassium Channels in Guinea Pig Papillary Muscles and Ventricular Myocytes
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此外,P-物质还抑制去极化激活的慢失活的钾电流、低阈值钙电流和超极化激活的内向整流(H或Q)电流。
In addition , substance P inhibited the slowly inactivated potassium current , low threshold ( T - ) calcium current and inward rectifier ( H - or Q - ) current .
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特异性增强心肌内向整流钾电流(I(K1))-抗心律失常新途径
Specifically Enhancing Inward Rectifier Potassium Current ( I_ ( K1 )): A New Antiarrhythmic Pathway
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心血管ATP敏感性钾通道(KATP)是受细胞内ATP浓度调控的一种内向整流钾通道。
ATP sensitive potassium channel ( K ATP ) in cardiovascular system is an inward rectifier potassium ion channel which could be modulated by intracellular ATP concentration .
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目的:研究高胆固醇血症对大鼠主动脉功能及主动脉平滑肌上内向整流和ATP敏感钾通道基因表达的影响。
AIM : To investigate the effects of hypercholesterolemia on functions of rat aorta and on gene expression of inward rectifier and ATP-sensitive potassium channels in aortic smooth muscle .
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激活G蛋白偶联的内向整流K+通道(G-protein-coupledinwardlyrectifyingpotassium,GIRK),可抑制VTA和黑质区神经元的DA释放。
Activation of G protein-coupled inwardly rectifying potassium ( GIRK ) can inhibit DA release of the neurons in the VTA and substantia nigra .
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Kir通道的共同特点是它们的内向整流特性,即钾离子内流较外流容易得多。这一特点使其在维持细胞正常兴奋性、保持血钾平衡等方面起发挥重要的生理作用。
The Kir currents show the inward rectification property that means potassium ion can flow into the cell more easily than flow out .
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HERG通道在去极化脉冲下由于存在快失活而呈内向整流性。
HERG channels were activated with depolarized pulse and expressed an inward-rectified propriety attributing to rapid inactivation .
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目的:研究未成年人心房肌细胞瞬间外向钾电流(I(to))和内向整流钾电流(I(Kl))的特性。
AIM : To study the properties of transient outward K + current ( Ito ) and inward rectifier K + current ( IK1 ) in immature human heart .
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该电流可能与内向整流钾通道(IK1)有关,但是与ATP敏感性钾通道和IKr无关。
The currents may be related with inward rectification potassium channel , but had nothing to do with ATP-sensitive potassium channel and IKr .
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明显抑制内向整流钾电流(IK1),尤其在超极化时;
Suppressed the inward rectifier K + current ( I KI ) significantly , especially at hyperpolarization ;
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【目的】体外诱导大鼠骨髓间充质干细胞(MSCs)分化为心肌细胞并探讨其内向整流钾电流(IK1)特征。
[ Objective ] To study the differentiation of rat bone marrow mesenchymal stem cells ( MSCs ) into cardiomyocytes in vitro and the characteristics of inward rectifier potassium current ( IK1 ) of induced cells .
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统计学结果表明在测试的所有小鼠心室肌细胞中,10μMadenosine使心内膜、外膜下细胞的内向整流电流分别增加了22.3%±3.9和49.6%±23.1(相对于基础电流)。
Our statistical results suggest that in all the mouse ventricular myocytes we measured , 10 μ M adenosine induced an increase of 22.3 % ± 3.9 and 49.6 % ± 23 in inward rectifier current ( versus the basal current ) in endocardial and epicardial ventricular myocytes , respectively .
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结果延胡索乙素可明显抑制延迟整流钾电流(IK)和内向整流钾电流(IK1),并呈剂量依赖性。
Results In ventricular myocytes of guinea pig , the delayed rectified potassium current ( I_K ) and the inwardly rectifying potassium current ( I_ K1 ) were blocked by THP in a concentration-dependent fashion .
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目的:研究蝙蝠葛碱对豚鼠心室肌细胞快激活(I(Kr))和慢激活(I(Ks))延迟整流钾电流及内向整流钾电流(I(K1))的作用。
AIM : To study the effects of dauricine ( Dau ) on the rapidly activating component ( Ikr ), the slowly activating component ( Iks ) of the delayed rectifier potassium current , and the inward rectifier potassium current ( Ikl ) in guinea pig ventricular myocytes .
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目的和方法:采用双微电极电压钳(TEV)法研究细胞外Mn2+对非洲爪蟾卵母细胞表达的内向整流钾通道(IRK1)的阻断作用。
Aim and Methods : Two microelectrode voltage clamp ( TEV ) method was used to study the blocking effects of extracellular Mn 2 + on the inward rectifier potassium channel ( IRK1 ) expressed in the Xenopus oocytes .
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宏观IACh呈内向整流和浓度依赖性。
The macroscopic I ACh was inward rectified and concentration dependent .
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Ba2+对基础内向整流电流的作用。
The effect of Ba2 + on the basal inwardly rectifying current .
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全细胞IACh呈较强的内向整流。
Furthermore , whole cell nAChR currents shows strong inwardly rectifying manner .
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视锥光感受器内向整流电流特性和功能
The properties and function of inward rectifying currents in bullfrog cone photoreceptors
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维司力农对培养鸡胚心室肌细胞内向整流性钾电流的作用
Effect of vesnarinone on inward rectifier potassium current in cultured embryonic ventricular myocytes
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青蒿素对蛙卵表达的克隆内向整流钾电流的抑制作用
Inhibition of Artemisinin on Cloned inward Rectifier Potassium Channels Expressed in Xenopus Oocytes
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硫喷妥钠对人心肌细胞内向整流钾通道电流的影响
Effects of thiopentone of inward rectifier K ~ + current in human atrial myocytes
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持续性心房颤动患者心房肌内向整流钾电流的研究
Human inward rectifying potassium current in myocytes isolated from patients with rheumatic atrial fibrillation