免疫逃避

Fas表达异常与肾癌免疫逃避的关系

Role of Fas expression in immune escape of renal cell carcinoma

结论P53可能通过免疫逃避作用使肿瘤细胞凋亡下降，但不是唯一因素。

Conclusions P53 might decrease tumor apoptosis by immune escape , but net the unique factor of immune escape .

FasL表达在肝癌肿瘤免疫逃避中的意义

Significance of the Expression of FasL in Tumor Immune Evasion of Liver Neoplasms

结论肾癌通过下调Fas表达实现免疫逃避。

Conclusion Down-regulation of Fas expression is one of mechanisms for RCC cells to escape immune attack .

肾癌Fas和FasL蛋白表达异常对其免疫逃避机制的影响

The Effect of Fas and FasL Abnormal Expression on Immune Escape Mechanism of Renal Cell Carcinoma

目的：探讨肝癌中FasL表达在肿瘤免疫逃避中的意义。

Objective To study the role of the expression of FasL in tumor immune evasion .

FasL的表达异常与膀胱癌组织类型及病理分级关系不密切，其所致的肿瘤免疫逃避作用可能是恶性肿瘤发展的基本原因之一。

Tumor escape induced by FasL might be one of the basic reasons in progression of neoplasm .

从免疫逃避来看，可能这个SNP是最大的问题。

In the escape from the immune response , perhaps the biggest question is this SNP .

结论癌组织表达Fas、FasL，可能参与癌细胞的免疫逃避；

Conclusions The expression of Fas , FasL protein may be related to the immunological escape of the cancer cell ;

目的：由于原发性肝癌（HCC）存在突变、免疫逃避、抗原性弱、血供丰富等因素导致其死亡率、复发率较高，现有治疗方案并不能改善不能手术的患者的预后。

Objective : The death and recurrence rates of HCC is rather high as its high mutation rate 、 immunity escaption 、 weak antigenicity and abundant blood supplement .

[结论]HPV感染可能会使宫颈癌细胞Fas基因表达下调，FasL表达上调，使癌细胞发生免疫逃避，从而促进宫颈癌的发生。

[ Conclusions ] The inhibition of Fas expression , and up-regulation of Fasl expression from HPV in cancer cells . Maybe promote development of cervical carcinoma .

结论CE复合物诱导人单核细胞的活化，并抑制成熟巨噬细胞炎性刺激下的活化作用，可能与结核菌免疫逃避和病理损害有关。

Conclusion CE induced pre-activation of monocyte , but inhibit differentiated macrophage activation induced by inflammatory stimulation . The immuno-modulation effect of CE might be correlated with MTB immune evasion and tissue destruction .

该文主要讨论HCV慢性感染的分子免疫学机制，包括由于基因突变导致的免疫逃避及HCV蛋白影响机体免疫功能的机制。

Here we discussed the molecular immune mechanisms of HCV persistence , including the immune evasion strategies evolved by this virus and the roles of HCV proteins in modulation of immune system .

肿瘤坏死因子受体（TNFR）是细胞因子受体家族中的一员，在大DNA病毒的免疫逃避中起着重要的作用。

Tumor necrosis factor receptor ( TNFR ) plays an important role in the evasion of immune response by large DNA viruses . TNFR is a homologue of cellular receptors .

与核衣壳蛋白有关的CTL免疫逃避的研究证实了CTL反应对于控制病毒感染的重要性。

Virus can exploit strategies to evade immune surveillance by CTL associated with NP , that indicates the importance of CTL response in controlling infection of virus .

pre-S/S基因变异可导致免疫逃避、隐匿性HBV感染，血清学检测时表现为HBsAg和HBsAb同时存在或HBsAg阴性。

Pre-S / S gene mutations can lead to immune escape and occult HBV infection , which show coexistence of HBsAg and HBsAb or HBsAg negative under the serological tests .

目的探讨肾癌临床化疗药物对肾癌Fas蛋白表达影响及Fas蛋白表达异常在肾癌免疫逃避机制中的意义。

Objective To investigate the effect of clinical chemotherapeutic drugs on Fas antigen expression of renal cell carcinoma ( RCC ) and the relation between Fas expression and the immune escape mechanism of RCC .

结论Fas/FasL系统在原发性肝癌肿瘤免疫逃避中起重要作用，Fas抗原表达在原发性肝癌门静脉癌栓形成中的作用值得进一步研究。

Conclusion These results implicate that the expression of Fas / FasL play an important role in cancerous tumor evasion , and Fas is worthy of further research on cancerous emboli in portal vein of HCC .

背景和目的：探讨（1）组织芯片运用的可行性；（2）Fas、FasL与结肠癌的免疫逃避的关系。

Background & Objective : ① To detect the feasibility of the application of TMAs and ② to investigate the role of Fas / Fas ligand ( FasL ) in tumor immune in colon adenocarcinoma .

我们猜测，与MHC和细胞因子调控有关的一些基因卷入到免疫逃避事件中，但是具体的每一个基因在感染了CSFV后有什么变化尚不清楚。

As we know , some genes relative to MHC and cytokine regulation are involved in persistent infection , but the extent of each gene responds to CSFV infection is unclear .

HBV表面抗原是介导HBV感染和诱导中和抗体的关键蛋白，表面抗原基因也是HBV基因组中的热点变异基因，表面抗原基因变异与HBV的免疫逃避以及对核苷类药物耐药密切相关。

HBV surface antigen ( HBsAg ) is the key protein that mediate the infection and induce neutralized antibody , although the HBsAg gene is hypervariable in HBV genome . HBV mutations are considered to be related with immune escape and nucleoside drug resistance .

结论Fas、FasL、Bcl-2及Bax的表达，可能与膀胱癌细胞的凋亡及免疫逃避等密切相关，影响膀胱癌的发生、发展和预后。

Conclusion The expression of Fas , FasL , Bcl-2 and Bax may play an important role in the process of apoptosis and immune evasion , and may be closely related to the pathogenesis and development of transitional cell carcinonma of bladder .

本研究对非小细胞肺癌反杀伤T淋巴细胞作了初步探讨，为进一步完善并建立肿瘤特异性CTL细胞模型提供依据并为研究肿瘤免疫逃避、免疫耐受等生物学行为奠定基础。

The present study investigated the killing of T lymphocytes by non-small-cell lung cancer cells , helping the establishment of tumor specific CTL models and providing a basis for studying the biological behaviors of tumors , such as immune escape and immune tolerance .

隆安县乙肝疫苗免疫逃避株的研究

Vaccine-induced escape mutant of hepatitis B virus in Long An County

甲胎蛋白在肝癌细胞免疫逃避中的作用机制

The role mechanism of alpha fetoprotein in escaping immune surveillance of hepatoma cells

传统的对寄生虫免疫逃避的解释有抗原变异、抗原伪装等等。

Conventional interpret about the mechanism involved antigen variation antigen disguise and so on .

肾癌免疫逃避机制的探讨

Mechanism of immune escape in renal cell carcinoma

结论：Fas/FasL系统在结直肠腺癌发生和免疫逃避中起重要的作用。

Conclusion : Fas / FasL plays an important role in tumorigenesis and immune escape .

目的探讨肿瘤免疫逃避与膀胱癌发生、侵袭及复发的关系。

Objective To clarify the relationship between tumor escape and the progression of bladder carcinomas .

Fas/Fas配体在结直肠腺癌发生和免疫逃避中的作用

The role of fas / fas ligand in tumorigenesis and immune escape in colon adenocarcinoma