光毒性

目的探讨采用单纯紫外线A（UVA）为照射光源的光毒性试验的影响因素及试验条件。

Objective To explore the influence factors and experimental conditions of phototoxicity test using pure UVA light source .

化学发光法定量检测药物光毒性

In vitro Quantitative Assessment of Drug Phototoxicity by a Chemiluminescence Method

体外3T3细胞光毒性中性红检测方法简介

Detection of photo-toxicity by Balb / c3T3 cell neutral red assay in vitro

目的研究3T3成纤维细胞中性红摄取试验（3T3NRUPT）在化妆品安全性评价中取代动物光毒性试验的可行性。

Objective To evaluate the3T3 Mouse Fibroblast neutral red uptake phototoxicity test ( 3T3 NRU-PT ) method detecting potential phototoxicity of cosmetic products .

另外一种相对普遍的现象则是光毒性反应。

Far more common is a phenomenon called phototoxic reaction .

皮肤活组织检查符合轻度光毒性皮疹或晒斑的表现。

A skin biopsy was consistent with a mild phototoxic eruption or sunburn .

基于组织工程皮肤的化学品光毒性检测

Phototoxicity test of chemicals based on tissue engineered skin

沥青光毒性皮炎19例报告

Phototoxic dermatitis caused by pitch & 19 case report

结论本研究中的卫生纸荧光增白剂不具有光毒性和致突变性，也非光敏物质。

Conclusion FWAs used in toilet paper has no phototoxicity , photoallergy and mutagenicity .

吡非尼酮灌胃小鼠的急性光毒性

The acute photo toxicity of pirfenidone in mice

目的建立化学发光法检测药物光毒性的模型。

Objective To establish a test model for phototoxic agents with the method of chemiluminescence .

光毒性试验方法研究

Study on Method for Phototoxicity Test

术中剥膜及止血未见明显并发症，术后1眼视网膜脱离复发，未发现光毒性反应。

Recurrence of retinal detachment was found in 1 eye , there was no evidence of phototoxicity .

化学品的安全性越来越受到人们的重视，光毒性的检测是其中的一项重要内容。

Nowadays , the public pays more attention on chemical safety , in which phototoxicity is one of the most important parts .

最近的研究成果推测：光毒性损伤，氧化应激损伤以及细胞因子异常表达在翼状胬肉的病理形成过程中起到一定的作用。

Recent data have provided evidence implicating photoxicity , oxidative damage , aberrant expression of cytokines in the pathogenesis of this disease .

长波长光的强穿透能力和对活体细胞和生物组织光毒性很小的特性，使得双光子激发荧光显微术已经成为无损伤成像的重要工具。

The two photon excitation microscopy has become an important tool of noninvasive imaging due to the better penetration and relative harmlessness of the longer wavelength .

这种光毒性作用以白光（混合波长光）最大，紫光和黄光次之，红光最小。

The strong'phototoxicity was produced by white light ( compound chromatic light ), medial by violet light or yellow light , and mild by red light .

蒽醌类化合物对大型溞（Daphniamagna）的急性光致毒性研究

Acute Photoinduced Toxicity of Anthraquinones to the Crustacean Daphnia magna

蒽醌类和多环芳烃类化合物对水生生物的急性光致毒性及QSAR研究

Acute Photoinduced Toxicity of Anthraquinones and Polycyclic Aromatic Hydrocarbons to Aquatic Organisms and QSAR Studies

UV照射诱导了荧蒽对卤虫幼体的氧化损伤，过氧化物酶（POD）对荧蒽的光诱导毒性较超氧化物歧化酶（SOD）敏感；

UV illumination induced the oxidative impairment of fluoranthene to nauplii . Peroxidase ( POD ) was more sensitive than superoxide dismutase ( SOD ) to photo-induced toxicity of fluoranthene .

花椒毒素纳米球对PUVA疗法光反应毒性影响的研究

Influence on PUVA Photoreaction Toxicity for Xanthotoxin-loaded Nanospheres

11种蒽醌类化合物对大型溞光敏化毒性的最佳OSAR模型的Q（cum）~2为0.902，具有较好的稳健性和预测能力。

Q_ ( cum ) ~ 2 of the final models of the toxicity of the tested eleven anthraquinones to Daphnia magna , were higher than 0.902 , indicating that the models have good predictive ability and robustness .

两种助溶剂不影响蒽醌类化合物对大型溞的光致毒性。

The two co-solvents , dimethylsulfoxide and acetone , did not affect the photoinduced toxicity of the compounds .

化合物最低未占据分子轨道能和最高占据分子轨道能之间的能级差，可用于初步判断蒽醌类化合物对大型溞的潜在光致毒性。

The gap between the energy of the highest occupied molecular orbital and the lowest unoccupied molecular orbital can be used as an indicator of the potential photoinduced toxicity of anthraquinones to Daphnia magna .

光和氧的毒性代谢产物引发晶状体脂质过氧化（LPO）的实验研究

The Experimental Research on Cataract Lipid Peroxidation Initiated by Toxic Metabolic Products of Light and Oxygen

羟基喜树碱（HCPT）因为其高效的抗癌效果，目前被广泛地应用于抗癌领域，由于它具有溶解度极低、见光易分解、毒性较大等特点，从而限制了HCPT的临床应用。

Hydroxycamptothecin ( HCPT ) has gained widespread interests for cancer therapy , as it has obvious antitumor effect . However , the low solubility , low photo-stability and high toxicity are the practical limits for clinical applications .