促肾上腺皮质激素释放激素
- corticotropin-releasing hormone
-
在抑郁症发病过程中,下丘脑-垂体-肾上腺轴的过度驱动和下丘脑室旁核(PVN)的促肾上腺皮质激素释放激素(corticotropin-releasinghormone,CRH)神经元的活性上调是抑郁症的重要特征。
A hyperfunction of the hypothalamus-pituitary-adrenal ( HPA ) axis and the hyperactivity of the corticotropin-releasing hormone ( CRH ) neurons in the paraventricular nucleus of the hypothalamus are the important neurophysiology symptoms of depression .
-
视黄酸受体通过对促肾上腺皮质激素释放激素神经元的调控参与抑郁症的发病促肾上腺皮质激素释放激素(CRH)被认为是应激反应的中枢驱动力并在抑郁症发病过程中起着关键作用。
The involvement of retinoic acid receptor - α in corticotropin-releasing hormone gene expression and affective disorders Corticotropin-releasing hormone ( CRH ) is considered the central driving force in the stress response and plays a key role in the pathogenesis of depression .
-
子痫前期患者血清及胎盘促肾上腺皮质激素释放激素(CRH)水平的变化及意义
The Significance of Serum and Placental Corticotropin Releasing Hormone ( CRH ) in Preeclampsia
-
下丘脑促肾上腺皮质激素释放激素(corticotropinreleasingfactor,CRF)肽是HPA轴的脑中枢调节者,它调节神经和体液两大系统。
Hypothalamic corticotropin-releasing hormone ( Corticotropin releasing factor , CRF ) peptide is brain central regulation of the HPA axis , which regulates the neural and humoral systems .
-
目的研究促肾上腺皮质激素释放激素(corticotropinreleasinghormone,CRH)对下丘脑神经元胞浆内cAMP浓度和Ca2+的调节作用。
Objective To study the regulatory effect of corticotropin releasing hormone ( CRH ) on cAMP level and intracellular Ca 2 + content in rat hypothalamic neurons .
-
大鼠动情周期中不同脑区促肾上腺皮质激素释放激素(CRH)含量的变化
Fluctuation of corticotropin releasing hormone levels in hippocampus , cerebral cortex , hypothalamus and pituitary tissues during oestrus cycle in rats
-
目的探讨促肾上腺皮质激素释放激素(corticotropinreleasinghormone,CRH)刺激下丘脑神经元表达CRH的信号调控机制。
Objective To investigate the signal regulatory mechanism of expression of corticotropin releasing hormone ( CRH ) stimulated neurons of hypothalamic slices in rats in vitro .
-
目的:观察肾上腺摘除新生大鼠下丘脑促肾上腺皮质激素释放激素(CRF)和精氨酸加压素(AVP)神经元对急性低氧的应答。
Aim : To investigate the response of hypothalamic corticotropin releasing factor ( CRF ) and arginine vasopressin ( AVP ) of adrenalectomized neonatal rats to hypoxia .
-
目的探讨大鼠下丘脑神经元表达促肾上腺皮质激素释放激素(CRH)mRNA的蛋白激酶A(PKA)信号调控机制。
Objective To investigate protein kinase A ( PKA ) signal regulatory mechanism of corticotropin-releasing hormone ( CRH ) mRNA expression , after CRH stimulated neuron of hypothalamic slices in rats in vitro .
-
[目的]观察加味四逆散(JSS)对慢性心理应激大鼠下丘脑促肾上腺皮质激素释放激素(CRH)及环核苷酸系统的影响。
[ Objective ] To investigate the regulatory effect of Jiawei Sini San ( JSS ) on psychological stress in rats with chronic psychological stress .
-
目的探讨G蛋白偶联受体激酶2/3(GRK2/3)在大鼠下丘脑室旁核促肾上腺皮质激素释放激素(CRH)分泌调节中的作用。
Objective To study effect of G protein-coupled recepter kinase 2 / 3 ( GRK 2 / 3 ) on the regulation of corticotrophin-releasing hormone ( CRH ) secretion in hypothalamic paraventricular nucleus ( PVN ) of rats .
-
子宫平滑肌间隙连接蛋白43、促肾上腺皮质激素释放激素、皮质醇与分娩发动的研究CRH在感染性早产胎盘滋养细胞中的表达
The relationship between CRH 、 cortisol and the expression of Cx-43 on myometrium before and during term labor . A study on the expression of CRH in infection-associated preterm labor placenta
-
目的研究G蛋白偶联受体激酶(GRK)在大鼠下丘脑的分布和严重创伤后时相变化及其与应激早期下丘脑促肾上腺皮质激素释放激素(CRH)分泌的关系。
Objective To study the distribution of G protein-coupled receptor kinase ( GRK ) in rats ' hypothalami and its role in the secretion of corticotrophin-releasing hormone ( CRH ) early after severe trauma .
-
结果如下:7km低氧暴露24h,大鼠下丘脑的促肾上腺皮质激素释放激素(corticotropin-releasingfactor,CRF)和肾上腺皮质激素皮质酮分泌显著增加,大鼠的HPA轴被激活。
Hypoxia with 7 km altitude exposed for 24 h resulted in increased corticotropin releasing factor ( CRF ) release from hypothalamus and corticosterone secretion in rat , the activity of HPA was stimulated by hypoxia .
-
目的探讨中药白松片对慢性应激大鼠行为学及血浆促肾上腺皮质激素释放激素(CRH)和促肾上腺皮质激素(ACTH)浓度的影响。
Objective To investigate the effects of Tablet Baisong ( TBS ) on the levels of CRH and ACTH in the plasma of modeling rats following chronic stress and on the behavior of these animals .
-
观察电针对关节炎症局部及下丘脑促肾上腺皮质激素释放激素(CRH)、β-内啡肽(βEP)、白细胞介素-2(IL-2)含量的影响,并比较不同穴位间的作用差异。
Effects of electroacupuncture on local joint inflammation and corticotropin-releasing hormone ( CRH ), β - endorphin (β - EP ) and interleukin-2 ( IL-2 ) contents in the hypothalamus were observed and differences of the actions among different points were compared .
-
目的观察穹窿切断对大鼠下丘脑促肾上腺皮质激素释放激素(CRH)表达的影响,探讨海马对HPA轴的抑制作用是否通过穹窿介导。
Objective To observe the effects of fornix transection on the expression of corticotrophin-releasing hormone ( CRH ) in the hypothalamus of rats , amd to discuss whether the hippocampus plays a role in the tonic neuronal inhibition of the HPA axis via the fornix .
-
HPA轴激活的中枢控制是十分复杂的,在这一系列神经内分泌调节过程中,下丘脑合成和释放的促肾上腺皮质激素释放激素(CRH)起着关键的作用,它控制着HPA轴的兴奋水平。
It is very complicated to control the activation of HPA axis in central nervous system . Synthesis and release of corticotropin-releasing hormone ( CRH ) from hypothalamus plays a key role in the regulation of the HPA axis . CRH controls the stimulating level of HPA axis .
-
额叶癫痫与促肾上腺皮质激素释放激素基因突变的关系
Frontal lobe epilepsy and mutations of the corticotropin-releasing hormone gene
-
妊娠期血浆促肾上腺皮质激素释放激素水平与分娩时间的关系
Study on relationship between plasma corticotropin-releasing hormone level in pregnancy and delivery time
-
乌头碱对大鼠下丘脑促肾上腺皮质激素释放激素含量的影响
Effect of Aconitine on Content of Corticotropin - Releasing Hormone in Hypothalamus of Rats
-
人胎盘促肾上腺皮质激素释放激素自身受体激活效应
Action of Corticotropin - releasing Hormone on Its Own Receptor Type-1 in Human Placenta
-
促黄体素释放素试验雌激素受体和视黄酸受体对促肾上腺皮质激素释放激素的调控
The Regulatory Effects of Estrogen Receptor and Retinoic Acid Receptor on the Corticotropin-releasing Gene Expression
-
应激与早产孕妇胎盘促肾上腺皮质激素释放激素信使核糖核酸的表达
Correlative study between stress and preterm birth expression corticotropin releasing hormone mRNA in women with preterm birth
-
可溶性细胞粘附分子1、促肾上腺皮质激素释放激素及白细胞介素6在妊娠高血压综合征发病中的作用
Role of Soluble Intracellular Adhesion Molecule-1 , Corticotropin-releasing Hormone and Interleukin-6 in the Pathogenesis of Pregnancy-induced Hypertension
-
胎盘组织中尿皮素和促肾上腺皮质激素释放激素2β受体表达变化与先兆子痫发病的关系
Study on the level of placental urocortin and corticotropin - releasing hormone receptor 2 β of preeclampsia
-
脐血促肾上腺皮质激素释放激素、皮质醇及硫酸脱氢表雄酮在足月分娩中的作用
Effect of corticotropin-releasing hormon , Cortisol and dehydroepiandrosterone sulfate in fetal umbilical cord blood for term labor
-
下丘脑室旁核区促肾上腺皮质激素释放激素Ⅰ型受体表达及信号通路的研究进展
Recent advances in research of expression and signal pathways of corticotropin-releasing hormone type ⅰ receptor in hypothalamic paraventricular nucleus
-
结论:逆灸、佐剂和逆灸后再接受佐剂3种情况对大鼠下丘脑中促肾上腺皮质激素释放激素、β内啡肽应激激素产生不同的影响。
CONCLUSION : Preventive moxibustion , adjuvant , and adjuvant after preventive moxibustion have different influences on hypothalamic corticotropin releasing hormone and beta endorphin of rats .
-
研究促肾上腺皮质激素释放激素受体的水平与分娩的关系,探索其结构,及其在应激、分娩中的病理生理学作用有着重要意义。
The research on relationship between CRH-Rs level and labor and exploration for their structure and the pathophysiological roles in stress and labor are of great significance .