乙酰胆碱酯酶抑制剂

一系列研究已证实乙酰胆碱酯酶抑制剂治疗VaD的作用，它不但能改善认知功能，而且还对脑功能恢复也有一定的益处。

A series of studies have suggested the effect of acetylcholinesterase inhibitors in the treatment of VaD . They can not only improve cognitive function , but also have certain benefits in recovering brain function .

乙酰胆碱酯酶抑制剂研究现状

Current Situation in the Research of Acetylcholinesterase Inhibitors

AD患者长期使用乙酰胆碱酯酶抑制剂的神经生理学预测因素

Neurophysiological predictors of long term response to AChE inhibitors in AD patients

乙酰胆碱酯酶抑制剂territremB类似物的合成新方法

The New Method for the Preparation of Territrem B Analogues as AChE Inhibitors

酒石酸卡巴拉汀是一种乙酰胆碱酯酶抑制剂，用于治疗中、轻度老年痴呆症（即阿尔茨海默氏症：AD），目前已在瑞士上市，市场前景看好。

Rivastigmine , a sort of acetylcholinesterase inhibitor , is used in the symptomatic treatment of mild to moderate Alzheimer 's Disease ( AD ) . Now it has been launched in Switzerland , and the market prospect is very good .

通过以上三方面的研究，希望能够指导分子优化设计和虚拟筛选出来高活性、高选择性乙酰胆碱酯酶抑制剂分子，减少在AD疾病治疗中乙酰胆碱酯酶抑制剂可能引起的副作用。

Through the research , we hope that it can provide a guide for the design of the molecular and can screen out AChE inhibitor molecules with high activity and high selectivity , reduce the side effects in the treatment of AD disease .

乙酰胆碱酯酶抑制剂Corydaline的分子对接与开环衍生物的虚拟筛选

Molecular Docking of the Acetylcholinesterase Inhibitor Corydaline and Virtual Screening of Open Ring Derivatives

使用TopomerCoMFA方法构建三维定量构效关系模型，为指导设计高活性和高选择性的乙酰胆碱酯酶抑制剂分子提供理论基础。

The models can provide theoretical basis for designing new high activity molecules . ( 2 ) Three-dimensional quantitative structure-activity relationship models were developed on a series of inhibitors of Acetylcholinesterase by Topomer CoMFA method .

乙酰胆碱酯酶抑制剂多奈哌齐可改善阿尔茨海默病患者的脑血管动态调节

Acetylcholine esterase inhibitor donepezil improves dynamic cerebrovascular regulation in Alzheimer patients

基于双中心理论的乙酰胆碱酯酶抑制剂研究进展

Advances in search for acetylcholinesterase inhibitor based on the double active sites hypothesis

乙酰胆碱酯酶抑制剂虚拟筛选方法研究

Method research on virtual screening of acetylcholinesterase inhibitors

乙酰胆碱酯酶抑制剂酶法筛选的探索研究

Pilot Study on Method of Selection for Acetylcholinsterase ( AChE ) Inhibition Enzymatic Measure

乙酰胆碱酯酶抑制剂的研究进展

Advances in the Research of Acetylcholinesterase Inhibitors

静脉用胺碘酮致严重肝功能损害一例他克林是一个选择性较好但毒副作用明显的乙酰胆碱酯酶抑制剂。

Tacrine is a selective acetylcholinesterase ( AChE ) inhibitor which has serious liver toxicity .

用途：第二代中枢性乙酰胆碱酯酶抑制剂，是一只具有高度选择性、可逆性治疗阿尔茨海默病（老年痴呆）的药物。

Usage : The second generation of central acetylcholinesterase inhibitor , used as a highly selective and reversible treatment of Alzheimer 's disease .

以28株可能产生物碱的内生真菌为出发菌株，通过乙酰胆碱酯酶抑制剂筛选模型，从中筛选出10株产乙酰胆碱酯酶抑制剂的内生真菌。

Through the screening of acetylcholinesterase inhibitors , ten strains of endophytic fungi producing acetylcholinesterase inhibitors were selected from the twenty-eight strains which produced alkaloids .

摘要石杉碱甲是一高效、高选择性乙酰胆碱酯酶抑制剂，由于其独特的药理特徵和低毒性，引起了人们的广泛注意。

Huperzine A has been shown to be a powerful selective inhibitor of acetylcholinesterase and has attracted widespread attention because of its unique pharmacological profile and low toxicity .

石杉碱甲是一种高效、高选择性乙酰胆碱酯酶抑制剂，是临床上治疗老年性痴呆具有很好疗效的一种中药有效成分。

Huperzine A is a powerful selective inhibitor of acetylcholinesterase and an effective component of the Chinese traditional medicines , which has good therapeutic effect on clinical therapy to the alzheimer 's disease .

作为一种神经系统乙酰胆碱酯酶的抑制剂，沙林可导致抽搐、呼吸停止和死亡。

As an inhibitor of the nervous system enzyme acetylcholinesterase , sarin can cause convulsions , stoppage of breathing and death .

目的：分离大鼠皮层乙酰胆碱酯酶G4和G1分子亚型以阐明乙酰胆碱酯酶抑制剂药物的作用。

To isolate the G4 and Gl molecular forms of acetylcholinesterase in rat cortex for interpreting the therapeutical effect of the AChE inhibitor drugs .