tfh

AIM : The influence of TFH on myocardial ischemic reperfusion injury was studied by observing pathological change of ultrastructure and level of SOD and MDA .

目的：观察沙棘总黄酮对大鼠心肌再灌注损伤时超微结构及对心肌组织SOD活性和MDA含量的影响。

Without IL-21 , the all-important TFH cells could neither develop nor survive .

没有IL-21，所有重要的辅助性滤泡T细胞既不能发育也不能生存。

The Development of TFH Sustained - released Capsule

TFH缓释胶囊的研制

TFH cells play a critical role in that they communicate with , and help activate , B cells .

辅助性滤泡T细胞在与B细胞之间传递信息以及辅助活化B细胞方面发挥关键作用。

In addition , we also observed that TFH could make the spontaneous abnormal beating of cell change into regular beating .

此外还观察到TFH可使异常自发搏动节律转为有规律的搏动。

TFH could also reduce Ca ~ ( 2 + ) - dependent contraction in rabbit aortic preparations .

TFH还可明显抑制家兔主动脉条Ca~（2+）内流依赖性收缩。

OBJECTIVE To prepare sustained-release Hippophae rhamnoides ( TFH ) tablet and evaluate the rule of drug release property .

目的评价醋柳黄酮缓释片的缓释效果并考察其体外释放规律。

Conclusion : TFH can effectively decrease the serum levels of TC , LDL-C , TG and increase serum level of HDL-C.

结论：醋柳黄酮能有效地降低TC、TG、LDL-C，升高HDL-C。

Conclusion It is a simple and efficient method to separate the TFH from H. rhamnoides leaves with FL-1 resin .

结论FL-1树脂用于沙棘叶总黄酮的分离纯化简便有效。

Roughly eight years ago , a new subset of T cells , T follicular helper ( TFH ) cells , was identified .

大约八年前，人们鉴定出一种新的T细胞，辅助性滤泡T细胞。

RESULTS Six weeks later , blood pressure in TFH was decreased 18.1 ± 8.2 / 12.4 ± 10.1 mmHg compared with that in Enalapril without statistical difference .

结果醋柳黄酮治疗6周后血压下降18.1±8.2/12.4±10.1mmHg，与依那普利的降压水平相似。

Method : Drug concentration of TFH and TFH-SLN in blood , heart , liver , spleen and kidney of mice after oral administration was determined by HPLC .

方法：采用HPLC法测定小鼠口服醋柳黄酮（TFH）和TFH-SLN后血液、心、肝、脾、肾的药物浓度。

Objective : To study a method to determine the concentration of TFH in mice plasma , then to compare the concentration of TFHC to that of TFH-SLN .

目的：研究醋柳黄酮在小鼠体内血药浓度的测定方法，比较醋柳黄酮胶囊和其口服固体脂质纳米粒在小鼠血液中的药物浓度。

The incidence of side effect in TFH group was 11.27 % ( 8 / 71 ), which was significantly lower than that of enalapril 29.6 % ( 21 / 71 ) .

醋柳黄酮组副作用发生率为1127%（8/71），明显低于依那普利组（296%，21/71）。

RESULTS : After 40 min ischemia and 30 min reperfusion TFH could obviously improve the development of ultrastructural pathological change at myocardial ischemic reperfusion areas and significantly increase the SOD activity and reduce the production of MDA in rats .

结果：缺血40min，再灌30min后TFH（77mg·kg－1、231mg·kg－1）能明显减轻缺血再灌损伤区超微结构的病理改变，显著提高大鼠心肌组织SOD活性并减少MDA的生成。