daz
- 网络达兹;无精症缺失
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Determination of the DAZ Gene in Human Sperm by Quantitative PCR
定量PCR法测定人精子中DAZ基因的相对含量
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Use of fluorescent PCR in diagnosis of male infertility related DAZ Gene
荧光PCR在男性不育相关DAZ基因检测中的运用
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Idiopathic male infertility and partial copy deletion of DAZ gene family
男性原发不育与DAZ基因家族部分拷贝缺失
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The clinical significance of DAZ and RBM gene detection in male infertility
男性不育症患者RBM、DAZ基因检测的临床意义
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Diagnosis of the DAZ gene deletion in human sperm of infertile men by quantitative polymerase chain reaction
定量聚合酶链反应法对不育患者精子中DAZ基因缺失的诊断
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Study on DAZ Gene Copy Deletion in Severe Oligozoospermia Sperm Donor for ICSI
严重寡精症ICSI精子供体的DAZ基因拷贝缺失研究
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Methods DAZ gene of peripheral blood leukocytes was detected by PCR technique in 38 azoospermia and 12 severe oligozoospermia patients .
方法应用PCR技术对50例无精子症和严重少精子症患者(其中无精子症38例,严重少精子症12例)的外周血细胞进行DAZ基因检测。
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Objective : To study the relationship of the sperm quality , DAZ ( deleted in azoospermia ) gene and the male infertility .
目的:探讨精子质量及DAZ(DeletedinAzoospermia)基因与男性不育症的关系。
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Analysis of Chromosomal Abnormality in Azoospermia Relationship between the entire DAZ genes as well as DAZ1 / DAZ2 deletion and azoospermia
无精症患者的染色体异常分析无精症DAZ基因缺失研究
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Results : 54 patients with chromosomal aberration , 3 patients with DAZ gene deletion and 5 patients with mutations in the exon A of androgen receptor gene were found .
结果139例原发不育患者G、C显带发现54例染色体核型异常,3例DAZ基因缺失,5例雄激素受体基因外显子A发生点突变。
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[ Objective ] To investigate the relationship of the entire deleted in azoospermia ( DAZ ) genes as well as DAZ1 / DAZ2 deletion and azoospermia .
目的探讨无精症患者的DAZ基因全缺失和DAZ1/DAZ2缺失。
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Objective To analyze the pattern and prevalence of partial copy deletion of deleted-in-azoospermia ( DAZ ) gene in the azoospermia factor C ( AZFc ) region of patients with idiopathic azoospermia or severe oligozoospermia .
目的分析原发无精症和严重少精症患者Y染色体无精症因子C区(azoospermiafactorC,AZFc)DAZ基因(deleted-in-azoospermia,DAZ)部分拷贝缺失的类型与频率。
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Conclusion RBM and DAZ genes are one of the important candidates for azoospermia factor ( AZF ) . Microdeletion on RBM and DAZ is a major cause of azoospermia and severe oligozoospermia leading to male infertility .
结论RBM和DAZ为无精子因子(AZF)的重要候选成分,RBM及DAZ微缺失是引起无精子和严重少精子并造成男性不育的重要原因之一。
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Methods Deletions in 25 azoospermic and 27 severe oligozoospermic Chinese patients were screened by STS PCR strategy . A total of 23 STSs in interval 6 of Yq , including 4 STSs in the deleted azoospermia gene ( DAZ ) region were analyzed .
方法运用STSPCR法对25例无精症和27例严重少精症患者的Y染色体interval6的23个序列标签位点(STS)进行缺失筛查。
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Conclusion The frequency of partial copy deletion of DAZ gene in Chinese idiopathic azoospermia or severe oligozoospermia patients is much higher than that of fertile controls , suggesting that the deletion of DAZ1 / DAZ2 may be one of the important genetic etiological factors of spermatogenesis damage .
实验组与对照组DAZ1/DAZ2共缺失率差异有极显著性。结论原发无精和严重少精症存在较高频率的AZFc区DAZ基因的部分缺失,这可能是中国男性原发不育的病因之一。
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[ Methods ] The entire DAZ genes and DAZ1 / DAZ2 deletion were analyzed by multiplex polymerase chain reaction ( multi-PCR ) and polymerase chain reaction-restriction fragment length polymorphism ( PCR-RFLP ) in 228 infertile patients with azoospermia and 252 normospermic men as controls .
方法应用多重PCR和PCR-RFLP技术,对252个正常生精男性和228例无精症患者的DAZ基因全缺失和DAZ1/DAZ2缺失进行了分析。