a02

K562 , K562 / A02 and clinic sample were used in the study .

蛋白质芯片检测多药耐药蛋白，是以细胞株（K562和K562/A02）、汉防己甲素和屈洛昔芬单独或联合作用的K562/A02耐药细胞及部分临床样品为实验研究对象。

Study on reversal effects of Oridonin on multidrug resistant cell line K562 / A02

冬凌草甲素逆转多药耐药细胞系K562/A02耐药性的研究

PSC 833 could increase DNR retention in K562 / A02 cells .

PSC833能增加K562/A02耐药细胞系的DNR潴留。

The cell growth inhibition of K5662 / A02 cells was assayed using MTT method .

实验方法：K562/A02耐药性以MTT法检测阿霉素抑制细胞生长作用，计算耐药倍数。

The Effect of Three Anthracycline Antineoplastic Drugs on K562 / A02 Cell Line Proliferation in vitro

三种蒽环类抗肿瘤药物对K562/A02细胞体外抑制作用

Establishment and Evaluation of a Model using K562 / A02 Multidrug Resistant Tumor Xenografts in Nude Mice

多药耐药细胞系K562/A02裸小鼠皮下移植瘤模型的建立与鉴定

Study of the effect of quercetin on expression of multidrug resistant gene and protein in K562 / A02 cells

槲皮素对K562/A02细胞多药耐药基因及糖蛋白表达的影响

Effect of Intracellular Acidification on P-glycoprotein in Drug-resistant K562 / A02 Cells

细胞酸化对K562/A02耐药细胞株中P-糖蛋白的影响

Study on Effect of Momordin on Reversion of Multidrug Resistance in K562 / A02 Cells

苦瓜蛋白对K562/A02耐药逆转作用的研究

Reversal effect of artesunate on the multidrug-resistance of human leukemia K562 / A02 cells

青蒿琥酯逆转K562/A02细胞对阿霉素耐药性机理的研究

Mechanism of tetrandrine in reversion of multidrug resistance of leukemic cell line K562 / A02

汉防己甲素逆转白血病细胞株K562/A02耐药的机制

Effect of 4 cytokines on intracellular accumulation of daunorubicin in K562 / A02

4种细胞因子对K562/S及其耐药细胞株K562/A02积蓄柔红霉素的影响

Study on reversal of drug resistance in K562 / A02 cells by antisense oligodeoxynucleotide targeting survivin

Survivin反义寡核苷酸逆转K562/A02细胞的耐药研究

Primary observation of reversal of multidrug resistance in K562 / A02 cells with Radix Angelicae sinensis

当归药物血清逆转K562/A02细胞对阿霉素耐药性的初步观察

CONCLUSION : Lomerizine could reverse the MDR in K562 / A02 cells by increasing the intracellular drug concentration .

结论：洛美利嗪对K562/A02细胞的ADM、VCR细胞毒性有剂量相关性增敏作用，其机制可能与增加细胞内药物浓度有关。

Moreover , the expression of MAGE-3 gene mRNA in K562 / A02 cells was higher than that in K562 cells .

此外，与K562细胞比较，K562/A02细胞MAGE3mRNA表达明显上调。

Functional study of mdrl and GST π expression reversed by hairpin siRNA in K562 / A02 cell line

发夹状siRNA逆转白血病K562/A02细胞株mdr1和GSTπ功能的研究

Effect of Tetrandrine Combined with Daunorubicin on Expressions of P21 and P-gp in K562 / A02 Cells

汉防己甲素联合柔红霉素对K562/A02细胞株P21蛋白和P糖蛋白表达的影响

Objective : To compare the effect of three kinds of anthracycline antineoplastic drugs on K562 / A02 cell line proliferation in vitro .

目的：比较表阿霉素，柔红霉素和吡喃阿霉素对多药耐药细胞株K562/A02体外增殖的抑制作用。

Study on the Relationship Between [ Ca ~ ( 2 + ) ] I and the MDR Formation in K562 / A02 Cells

细胞内钙与K562/A02细胞多药耐药相关性的研究

Enhancement of cytotoxicity of anthracycline antineoplastic drugs by neferine in K562 / A02 cells

甲基莲心碱增强蒽环类药物对K562/A02细胞增殖抑制作用实验研究

Objective To study the effect of thapsigargin on chemotherapeutic sensitivity in multidrug-resistant leukemia cell line K562 / A02 induced by ADM.

目的探讨内质网Ca2+ATP酶抑制剂thapsigargin对白血病多药耐药细胞株K562/A02化疗敏感性的影响。

Conclusions Antisense oligonucleotides complementary to CYP3A5 gene may obviously reverse the drug-resistant phenotype of K562 / A02 cells .

结论：针对CYP3A5基因的反义寡核苷酸可显著逆转K562/A02细胞的耐药性。

Apoptosis of Multidrug-resistant Human Leukemia Cell Line K562 / A02 Induced by Fraction C ⅱ from Naja Naja Actra Venom

中华眼镜蛇毒组分CⅡ诱导多药耐药白血病细胞K562/A02凋亡

Decrease of cellular GSH concentration may be one of the MDR reversal mechanisms in K562 / A02 cell line by neferine and erythromycin .

结论：细胞内GSH含量增高是K562/A02细胞产生MDR的机制之一；Nef，EM能使K562/A02细胞内GSH含量下降可能是其逆转耐药白血病细胞MDR的机制之一。

Morphological change of K562 / A02 cells treated with thapsigargin was examined with AO / EB fluorescent staining under fluorescent microscopy .

丫啶橙（AO）/溴化乙锭（EB）染色荧光显微镜观察thapsigargin处理后K562/A02细胞形态改变；

Objective To study the molecular mechanism underlying multidrug resistance ( MDR ) and identify unknown genes that might be involved in drug resistance development in K562 / A02 cells .

目的分析K562/A02细胞多药耐药性（MDR）分子机制，寻找可能参与K562/A02细胞耐药机制的新基因。

In conclusion , the mechanism of Tet and DRL reversing multidrug resistance has no correlation with the apoptosis of K562 / A02 cells .

结论：汉防己甲素，屈洛昔芬逆转耐药的机理与诱导K562A02细胞凋亡无关。

50 % inhibition concentration ( IC_ 50 ) of doxorubicin ( ADM ) for K562 / A02 cell line was determined by MTT method .

MTT法检测阿霉素对K562/A02细胞半数抑制浓度（IC50）。

Methods : After treatment with TNF - α and IFN - α respectively , K562 / A02 sensitivity to ADR was investigated using tetrazolium dye assay .

方法：应用MTT法，分析TNFα和IFNα（均为100U/ml）分别处理K562/A02前后，K562/A02对ADR敏感性的变化。