PARP

Structure and Function of PARP and Its Relation to DNA Injury

PARP的结构、功能及其与DNA损伤的关系

PARP may play an important role in the colon adenocarcinoma growth and metastasis .

PARP在结肠癌生长和转移过程中可能具有重要作用。

PARP is one of the most important substrates of caspase-3 .

PARP是Caspase-3最重要的底物之一。

Characteristics of the deletion of integrated genes induced by inhibitor of PARP

PARP抑制剂诱导外源整合基因删除的作用特点

Effects of Lowering PARP Enzyme Activity on the Stable Integration of the Exogenous Gene

降低PARP酶活性对外源基因稳定整合的影响

Effect of ursolic acid on caspase-3 and PARP expression of human MCF-7 cells

熊果酸对乳腺癌细胞caspase-3和PARP表达的影响

Implications of PARP expression in hepatocellular carcinoma and cirrhosis tissues

PARP在原发性肝癌和肝硬化组织中的表达及意义

Comparison of PARP activity and spontaneous DNA breakages between leukemic cells and normal peripheral blood lymphocytes

白血病细胞与正常外周血淋巴细胞的PARP活性及本底DNA链断裂的比较研究

The inhibition of PARP and Calpain can prevent and cure cerebral ischemic damage .

PARP与Calpain抑制剂对缺血性脑损伤的防治具有非常重要的意义。

Role of PARP and caspase-3 in the airway epithelial injury induced by peroxynitrite

多聚（ADP-核糖）聚合酶和半胱天冬蛋白酶-3在过氧亚硝基阴离子致气道上皮细胞损伤中的作用

To estimate the relative risk and the population attributable risk percent ( PARP ) of main risk factors by comprehensive analysis .

利用综合分析方法估计我国人群三种肿瘤的主要危险因素的相对危险度及人群归因危险度百分比。

Death substrate ( PARP ) and apoptosis

死亡底物PARP与细胞凋亡

Study on the Difference of DNA Damage and Repair Between the Normal Cell and Its Carcinomatous Cell After Treatment with PARP ′ s Inhibitor

NIH3T3细胞与其癌变细胞的PARP酶被抑制后DNA损伤修复的差异研究

Study on the Association between PARP and Rho-Kinase on Apoptosis Induced by Ischemia / Reperfusion Injury in Neonatal Rat Myocardial Cells

Rho激酶与PARP在乳鼠缺血再灌注心肌细胞凋亡中关系的研究

Role of PKC-MAPK Pathway and PARP in Neurodevelopmental Toxicity by Prolonged Low Level Exposure of MMC

PKC-MAPK信号通路及PARP在长期接触低剂量氯化甲基汞所致脑发育损伤中的作用

Expressions of PARP and TRAP and their clinicopathological significances in the benign and malignant lesions of gallbladder

胆囊良恶性病变组织中PARP和TRAP表达及其临床病理意义

Construction of antisense PARP cDNA recombinants and establishment of the HeLa transformant after antisense plasmid introducing

反义PARP基因真核表达重组体的构建及其HeLa转化细胞系的建立

The projection of the structure of eulytite and the cell parp - meter of BGO are given .

给出eulytite的结构投影和BGO晶体的点阵常数。

Studies on Reversion of a Transformant Line and Loss of Exogenous ras Oncogene after Treatment with an Inhibitor of PARP Enzyme

PARP酶抑制剂诱导转化细胞逆转及外源ras癌基因丢失的研究

PARP , as a death substrate , involving in the execution of apoptosis is one of the hottest area of modern biology in home and abroad .

PARP酶作为死亡底物参与凋亡的实施是近年国内外现代生物学研究的热点之一。

The population attributable risk percentage ( PARP ) of all causes of death for smokers was 2.5 times of that for dust exposed workers .

人群死亡归因危险度百分比（PARP）吸烟者是接尘者的2.5倍。

With the PARP inhibitor ABT-888 increased the concentration along , PAR inhibited the expression of that PARP activity was inhibited .

随着PARP-1抑制剂ABT-888的浓度的增高，PAR的表达也受到抑制，即推测PARP-1的活性也受到于制。

Objective To investigate the expression of Poly ADP-Ribose Polymerase ( PARP ) and morphological changes after varies duration of retinal ischemia reperfusion in rats .

目的观察大鼠视网膜缺血再灌注损伤后不同时相视网膜结构变化及多聚二磷酸腺苷核糖聚合酶（PARP）的表达情况。

Z-DEVD-fmk may decrease PARP cleavage by inhibiting activity and auto-activation of caspase-3 , and prevent the injured neurons from apoptosis .

zDEVDfmk可通过抑制caspase3活性和自活化，减少PARP切割灭活，阻止受损神经元凋亡。

Expression of apoptosis-related proteins ( Caspase-3 , Caspase-8 and poly ADP-ribose polymerase ( PARP )) was determined by immunohistochemistry .

利用间接免疫荧光技术和免疫细胞化学技术检测细胞内凋亡相关蛋白Caspase-8、Caspase-3以及死亡底物聚ADP核糖聚合酶[poly（ADP-ribose）polymerase，PARP]的表达活性变化。

Western blot assay was applied to detect the protein-expression changes of caspase 3 and its substrate PARP during the aloe-emodin-induced apoptosis .

应用westernblot方法检测细胞凋亡过程中caspase3及PARP蛋白的表达变化情况。

When DNA damages of cells appear , as a kind of molecular sensor of cells , PARP will recognize and bind to DNA breakages , then be activated .

当细胞DNA发生损伤时，PARP可作为细胞内的分子感受器，识别、结合到DNA断裂处，并被激活。

Poly ( ADP-ribose ) polymerase ( PARP ) is a post-translational modification enzyme which exists in eukaryote cells , except yeasts .

多聚ADP核糖聚合酶（PolyADP-ribosepolymerase，PARP）是广泛存在于除酵母以外真核细胞中的蛋白质翻译后修饰酶。

Taeho Kim and others reported in2001 that biological selenium can promote apoptosis and division of PARP and activity of Caspase-3 , while sodium selenite cannot ;

TaehoKim等2001年报道生物硒能够提高腺苷二磷酸-核糖聚合酶（PARP）凋亡分裂和半胱天冬酶-3活性，而亚硒酸钠不行；

During the course of TNF α - induced cell death , the DNA repair enzyme , poly ( ADP-ribose ) polymerase ( PARP ) was not degraded .

在TNFα诱导L929细胞凋亡过程中，细胞核内的DNA修复酶poly-（ADP-ribose）polymerase（PARP）未被降解。