3TC

Anti-virus effect of combination of attenuated measles virus with 3TC on duck hepatitis B model

减毒麻疹病毒联合拉米夫定体内抗鸭乙型肝炎病毒作用的研究

The effects of 3TC and IFN a in various concentrations on development of embryos were observed .

采用微滴培养法连续培养72h，对比观察不同浓度3TC和IFNα对体外胚胎细胞早期发育的直接影响。

Objective To evaluate the anti virus effect of combination of attenuated measles virus with 3TC on duck hepatitis B model .

目的观察减毒麻疹病毒与拉米夫定（3TC）联合用药在鸭体内抗乙型肝炎病毒的作用。

Efficacy of 3TC + D4T + NVP Regimen Anti-HIV-1 Treatment and Drug Resistance Mutations

3TC+D4T+NVP方案抗HIV-1治疗效果评价及耐药性的研究

Experimental Study on the Effect of JIA WEI SI NI SAN Decoction Anti-DHBV 3TC Persister and the Effect of Anti-inflammatory and Anti-lipid Peroxidation

加味四逆散抗DHBV3TC耐药株和抗炎、抗脂质过氧化作用的实验研究

Objective To summarize progresses of chemosynthesis and biological activity of lamivudine ( 3TC ) and its analog ( - ) FTC .

目的综述抗病毒药拉米夫定（3TC）及其类似物（-）FTC的化学合成、药理活性研究进展。

Lamivudine ( 3TC ), an anti-HIV nucleotide analog , is a promising drug developed in recent year for treat-ing of HBV persistent patient .

拉米呋啶（Lamivudine）是近年来开发成功的一种治疗HBV慢性感染病人的核苷类药物。

Positive control group , combivir ( AZT / 3TC ) , was given by intragastrical administration with 200 mg · kg-1 · day-1 for consecutive 14 days .

阳性对照组用双汰芝（200mg·kg-1·d-1）灌胃，连续给药14d。

Furthermore , the combination of 3TC and PA can not only slowed down the 3TC absorption rate in rats to increase their uptake , but also significantly slow down the absorption and the elimination speed of PA in rats , extended their duration of action in vivo .

PA与3TC合用，不仅能明显减慢3TC在大鼠体内的吸收速度、增加其吸收总量，也能明显减慢PA在大鼠体内的吸收与消除速度、延长其体内作用时间。