麝香酮

麝香酮对谷氨酸所致PC12细胞损伤的保护及作用机制研究

Protective effects and machanism of muskone on pheochromocytoma cell injure induced by glutamate

麝香酮对完全性脑缺血大鼠的保护作用

Protective Effects of Muskone on Rats with Complete Cerebral Ischemia

（±）-麝香酮和（R）-麝香酮的自由基扩环合成法

A Synthesis of (±) - and ( R ) - Muscone by Radical Ring Expansion

运用彗星试验检测麝香酮对苯并（a）芘致DNA损伤的影响

A Study of Effect of Musk Ketone on Benzo ( a ) pyrene-induced DNA Damage by Comet Assay

采用HPLC和GC法分别测定了东莨菪碱和麝香酮的含量。规定了乌头碱的限量检查。

The content of scopolamine and muscone were determined separately by HPLC and GC .

手性助剂诱导下的α，β-不饱和酮的不对称加氢反应及其在合成（R）-麝香酮中的应用

Asymmetric Hydrogenation of α,β Unsaturated Ketones in the Presence of Chiral Auxiliaries & Preparation of ( R ) Muscone

HPLC-MS在麝香酮分析中的应用

Application of HPLC - MS to analysis of muscone

麝香酮抑制血管内皮细胞与中性粒细胞黏附及其表面ICAM-1、VCAM-1和CD44表达

Inhibitory effects of muscone on PMNs adherence to HUVEC and the expression of ICAM-1 , VCAM-1 and CD44 of HUVEC

麝香酮至少是麝香中增强NGF生物效应的最有效成分之一。

Among all of moschus ingredients , muscone is one of the most effective , enhancing the biological effect of NGF , at least .

大鼠、家兔和狗之间的药代动力学过程存在着显著的种属差异，大鼠iv麝香酮12,18和24mg/kg三种剂量间的药代动力学主要参数无显著性差异。

Significant species differences were observed in the pharmacokinetic parameters among rats , rabbits and dogs , while no significant differences were found among the three dosages of 12,18 and 24 mg / kg after iv administration to rats .

结果：对6个不同批次的醒脑注射液采用本方法进行测定，本品含麝香酮每1ml在0.030～0.038mg之间。

RESULT : Muscone has 0.030 mg ~ 0.038 mg per ml in Xin'nao injection according to muscone date of six samples of different lot number .

目的：研究麝香酮对大鼠局灶性脑缺血模型不同缺血时间海马神经元谷氨酸转运体EAAC1在转录水平表达的影响。

Objective : To investigate the effect of muscone on neuronal glutamate transporter EAAC_1 transcriptional level at different is-chemic times in acute ischemic hippocampus in rats .

合成麝香酮（dl-3-甲基十五环酮）及其杂质分析

The analysis of synthetic Muscone ( dl-3-methylcyclopentadecanone ) and its impurities

大鼠血浆和脑组织中麝香酮含量的测定

Quantitative Determination of Muscone in Rat Plasma and Brain

MS/MS目标化合物分析法鉴定中药中的麝香酮

Identification of Muskone in Chinese Medicines by MS / MS Targeted Compound Analysis

麝香酮对急性脑缺血损伤大鼠神经元谷氨酸转运体的影响

Effect of Muscone on Neuronal Glutamate Transporter of Acute Cerebral Ischemia in Rat

麝香酮抗局灶性脑缺血损伤的实验研究

Study of protection of muscone against local cerebral ischemia

人工合成麝香酮对小鼠早期妊娠的影响

Effects of synthetic Muskone on early pregnancy in mice

用气相色谱法测定麝香酮的含量。

The content of muscone was determined by GC .

论述了到目前为止反映在麝香酮结构上的混乱。

Confusion on the structure of muscone was discussed ;

4种中成药中微量麝香酮的毛细管气相色谱测定

Determination of Muscone in four species of Chinese patent medicines by capillary gas chromatography

~3H-麝香酮显微放射自显影研究

Study on ~ 3H-muscone by micro - autoradiography

麝香酮对易卒中型肾血管性高血压大鼠血浆内皮素和脑血管重塑的影响

Effects of Muscone on Plasma Endothelin and Cerebral Vascular Remodeling in Stroke-prone Renovascular Hypertensive Rats

麝香酮及长链二酮的仿生合成

Biomimetic Synthesis of Muscone and Long-chain Diketones

麝香酮的GC&MS联用定量分析方法研究

Quantitative Determination of Muscone by GC-MS

此外还对麝香酮色谱峰纯度作了色质联用分析，确定了本法所分离的麝香酮色谱峰是单一组分峰。本法简便、准确，并且重现性较好。

GC & MS was used to ana-lyse the purity of the chromatographic peak of muscone .

目的：探讨麝香酮减轻兴奋毒性、抗急性脑缺血损伤的作用。

Objective : To study the effect of muscone on attenuating excitotoxity and brain damage in acute cerebral ischemia .

目的建立腰痛灵栓中桂皮醛的含量测定及麝香酮鉴别的方法。

Objective To establish a method for the determination of cinnamaldehyde and qualitative identification of muscone in Yaotongling suppository .

方法采用气相色谱法，以麝香酮含量为测定指标，分别对人工麝香β环糊精包合物和混合物进行强光照射、高温、高湿和挥发性试验。

METHODS The stability of artificial moschus β cyclodextrin inclusion complex and the mixture were studied by determining the changes of muscone contents by GC after subjected to lamp light , high temperature , high humidity and volatility test respectively .

结果：麝香酮HP-β-环糊精分子包合物以及脂质体后的经皮渗透速率明显大于麝香酮，麝香酮β-环糊精包合物则较低。

Result : Among the different inclusion complexes and liposome , the penetrating rate of muscone in the HP - β - cyclodextrin inclusion and the liposome were higher than muscone , and that of muscone in the β - cyclodextrin inclusion is the lowest .