链脲霉素
- 网络Streptozotocin;STZ;streptozocin
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方法:给大鼠灌胃3个不同剂量的牛初乳粉(BCP)溶液15d后腹腔注射链脲霉素(STZ)55mg/kg。
Methods : The solution of BCP ( three different doses ) had been poured into stomach of rats for 15 days . Then STZ ( 55mg / kg ) were injected into abdominal cavity of them .
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选用纯系Lewis大鼠,用链脲霉素诱导成糖尿病模型,在同系间成功地施行了全胰十二指肠肾脏整块联合移植,手术成功率82.6%。
Diabetic models were induced by intravenous STZ injection in inbred lewis rats and en bloc transplantation of pancreas , duo (?) enum and kidney ;
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链脲霉素引起的高血糖抑制大鼠杏仁核点燃发展进程(p0.01)。
Streptozocin induced hyperglycemia significantly inhibited amygdala kindling development ( p0.01 ) .
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方法采用44只SD大鼠尾静脉注射链脲霉素的方法,建立超负荷血糖模型。
Methods Hyperglycemia model was made by intravenous injection of streptozocin in 44 SD rats .
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醛糖还原酶抑制剂对链脲霉素糖尿病小鼠眼晶状体代谢影响、ATP酶及抗氧化性防御的评价:一项干预性研究
Evaluation of an aldose reductase inhibitor on lens metabolism , ATPases and antioxidative defense in streptozotocin-diabetic rats : an intervention study
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目的:观察糖肾复元汤对链脲霉素(STZ)糖尿病肾病大鼠的疗效。
Objective : To observe Tangshen Fuyuan decoctions effect on DN rats due to STZ .
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方法:采用化学药品链脲霉素(streptozotocin)制备小鼠糖尿病模型,用葡萄糖氧化酶法测小鼠血糖含量。
Method : Using chemicals streptozotocin prep rats diabetes model ; to measure rats blood-sugar content with glucose oxidase method ;
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PL-AG比AG更有效的抑制链脲霉素糖尿病大鼠体内脂质过氧化。
The inhibitory activity of PL-AG against lipid peroxidation in diabetic rats was higher than that of AG .
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AG给药后引起链脲霉素糖尿病大鼠肝磷酸吡哆醛含量严重低下,但PL-AG仅仅轻度影响肝磷酸吡哆醛含量。
AG dramatically decreased the pyridoxal phosphate level of diabetic rat liver , whereas PL-AG only moderately affected it .
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目的:探讨大鼠侧脑室注射链脲霉素(Streptozotocin,STZ)阻断脑内胰岛素信号传导与Aβ表达的关系。
AIM : To investigate the effect of intracerebroventricular administration of streptozotocin ( STZ ) on expression of A β in rat brain .
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目的观察钒酸盐(Va)对链脲霉素诱导的糖尿病(DM)大鼠肾脏功能和结构的影响。
Objective : To study the effects of Vanadate ( Va ) on renal function , and structure in streptozotocin induced diabetic rats and to provide the experimental bases for clinical application of Va.
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【方法】1.采用链脲霉素(streptozotocin,STZ)60mg/kg尾静脉一次性注射法诱导建立Wistar大鼠Ⅰ型糖尿病模型。
Methods 1 . The diabetes Wistar rats were induced by intravenous administration of streptozotocin ( STZ ) in a single dose of 60mg / kg via penis dorsal vein .
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苦瓜素(14,28,56mg/kg)能降低链脲霉素诱发高血糖大鼠的血糖及HbA1C,能推迟大鼠口服蔗糖后血糖升高时间及降低血糖峰浓度。
MCE ( 14,28,56 mg / kg ) postponed the increase of the blood sugar level and decrease the peak sugar concentration of the rats after taking sucrose .
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糖尿病模型由一次性注射链脲霉素(STZ)获得,通过注射STZ获得的糖尿病模型是胰岛素依赖型糖尿病,即一型糖尿病。
Diabetes was induced by a single injection of streptozotocin ( STZ ) . The form of diabetes mellitus induced by parenteral STZ administration in rats is insulin-dependent ( type I ) .
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方法腹腔注射小剂量链脲霉素(streptozotocin,STZ),30mg/kg轻度损伤胰岛β细胞,造成大鼠糖耐量异常后加喂高果糖高脂肪饲料,并饮用10%果糖水,造成胰岛素抵抗。
Methods Female Wistar rats were injected a low dose of streptozotocin ( 30mg / kg ) intraperitoneally followed by a high fat high fructose diet and drank 10 % fructose water .
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方法采用正常小鼠,葡萄糖致高血糖小鼠,链脲霉素(STZ)诱发的糖尿病小鼠,用葡萄糖氧化酶法测定血糖值。
METHOD Normal mice , glucose induced hyperglycemic mice and streptozotocin ( STZ ) induced diabetic mice were used in this study ; The serum glucose concentrations were determined by method of glucose oxidase .
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方法利用hFasL转基因小鼠,用低剂量的链脲霉素(STZ)来诱导糖尿病。
Methods : Low dose injections of STZ were used to induce type I diabetes mellitus in the CMV-human Fas-ligand ( hFasL ) transgenic mice .
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目的:探讨链脲霉素(Streptozotocin,STZ)诱导的糖尿病鼠视网膜β-连环蛋白(β-catenin)表达以及与早期糖尿病视网膜病变发展的可能关系。
· AIM : To study the expression of β - catenin in streptozotocin ( STZ ) - induced diabetic rat retina and the possible relevance of β - catenin in the early stage of STZ-induced diabetic retinopathy .
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注射链脲霉素后9d以上时进行胰岛移植,在无生理盐水负荷的条件下,全部出现PNF,两者差异显著(P<001)。
Results ① Islet graft primary nonfunction did not appear in any diabetic rats within the 4 ~ 7 days after injection of STZ , but appeared in all recipients without normal saline loading 9 days later after injection of STZ ( P < 0 01 ) .
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海藻提取物对链脲霉素糖尿病大鼠的降血糖作用
Anti-diabetic effects of extractives of Marine algae in streptozotocin-induced diabetic rats
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链脲霉素所致糖尿病大鼠主动脉胶原非酶糖化的观察
Aortic Collagen Nonenzymatic Glycosylation Level in Streptozotocin-induced Diabetic Rats
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方法建立链脲霉素诱导的大鼠糖尿病模型。D组:糖尿病组;
Methods Rats were made diabetic with streptozotocin . group D , streptozotocin - induced diabetic rats ;
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方法腹腔注射链脲霉素(50mg/kg)制作糖尿病大鼠模型。
Methods : Diabetic rats established by abdominal injection of streprotozin ( 50mg / kg ) were taken as the model group .
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目的观察罗格列酮对由链脲霉素引起的2型糖尿病大鼠模型的血清胰岛素、肝细胞胰岛素受体及血糖的影响。
OBJECTIVE To observe the effect of rosiglitazone maleate on insulin sensitizing and blood lipid level of diabetic rats induced by streptozotocin .
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侧脑室注射链脲霉素引起大鼠脑Aβ(1-40)和Aβ(1-42)表达增加
Expression of A β _ ( 1-40 ) and A β _ ( 1-42 ) after intracerebroventricular injection of streptozotocin in rats
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本研究重点观察苦瓜对链脲霉素诱导的糖尿病大鼠肾脏硫酸类肝素的调节作用。
In the present investigation , effect of bitter gourd on streptozotocin-induced diabetic rats with particular emphasis on kidney heparan sulfate ( HS ) was studied .
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方法给正常和链脲佐霉素(STZ)诱导的糖尿病小鼠食用添加一定量豆渣粉的饲料5周,观察和测定相应指标。
[ WT5FZ ] Method : Normal mice and mice with streptozotocin ( STZ ) induced diabetes ( MD ) are given feed containing a certain amount of soybean fibers .
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Ⅰ组为正常对照组,Ⅱ、Ⅲ组动物静脉内注射链脲菌霉素(STZ)导致糖尿病,Ⅲ组于注射STZ3周末开始每日灌饲复方鱼油,实验结束时取血检测血浆脂质水平。
Group ⅰ was the normal control , group ⅱ and ⅲ were induced diabetic with streptozocin ( STZ ) injection . Three weeks after injection , group ⅲ was fed with fish oil compound . At the end of the study , plasma lipids were assayed .
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口服富铬啤酒酵母对链脲佐霉素诱导糖尿病大鼠的生物效应
Biological effects of chromium-rich brewer yeast in STZ-induced diabetic rats
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葫芦巴粗提物对链脲佐霉素诱导的糖尿病大鼠骨密度的作用
Effect of Crude Extract of Trigonella on Bone Mineral Density in Rats with Streptozotocin-induced Diabetes Mellitus