遗传毒性

结论钬化物对小鼠骨髓细胞具有一定的遗传毒性，DNA断裂作用可能是其分子机制之一。

Conclusion Holmium ions of rare earths have genotoxicity to bone-marrow cells of mice , and DNA breakage may be one of its molecular mechanisms .

MTBE及其代谢产物具有一定的遗传毒性和轻微的生殖毒性；

MTBE and its metabolites have some genotoxicity and a little reproductive toxicity ;

几种代谢和抗代谢药物对λDNA的遗传毒性分析

Analysis of genetic toxicity of several metabolic and anti-metabolic chemicals to λ DNA

铅化合物体外诱导人的淋巴细胞DNA损伤的遗传毒性

Effect of Pb Compounds on DNA Breakage Capacity in Vitro in Human Lymphocytes

22种化学物和紫外线对λDNA的遗传毒性分析

Analysis of genetic toxicity of 22 chemicals and ultraviolet ( uv ) to λ dna

结论甲醛能引起离体小鼠睾丸细胞不同程度的DNA损伤，对小鼠睾丸细胞具有生殖遗传毒性。

Conclusion Formaldehyde may cause DNA damage in isolated mice testicular cells in various degree .

苯DNA加合物的组织分布及其与细胞遗传毒性的关系

DNA adducts distribution in tissues and it 's correlation with cytotoxicity in mice exposure to benzene

结论甲基叔丁基醚在DNA水平和染色体水平有一定的遗传毒性作用。

Conclusion MTBE produced in the domestic had some genotoxicity at DNA level and chromosome level .

目的了解摩托车使用无铅汽油后其尾气对DNA的遗传毒性作用。

Objective To research the DNA damage and semina deformity of motorbike exhaust using lead-free gasoline .

氯化饮用水的煮沸效果遗传毒性变化和对细胞色素P450及其自由基效应影响的研究

Study on Effects of Boiling of Chlorinated Drinking Water Change of Genotoxicity and Influence on Cytochrome P-450 and Induction of Chemiluminescence

综述了遗传毒性化学物质与DNA的加合作用，以及DNA加合物形成后在致癌作用中的影响。

Review on combination of genotoxic chemicals with DNA and the effects of DNA adduct formation on carcinogenesis were presented .

目的研究甲醛对小鼠胸腺淋巴细胞DNA的交联作用，探讨甲醛的遗传毒性作用及机制。

Objective To explore the DNA cross-links in thymocytes of formaldehyde exposed mice and explore genotoxic effects of formaldehyde and possible mechanism .

被动吸烟对Wistar大鼠的遗传毒性作用

Genotoxicity Effects of Passive Smoking on Wistar Rats

目的：通过研究燃汽油机动车尾气成分，及其对DNA分子的氧化损伤，在分子生物学水平上探讨燃汽油机动车尾气污染物的遗传毒性效应与机制。

Objective : The genotoxicity and its molecular mechanism of gasoline vehicle exhaust were studied through examining exhaust components and the oxidative DNA damage induced by them .

目的通过研究丙烯醛对DNA分子的损伤，探讨丙烯醛的遗传毒性效应及其分子机制。

Objective To study the genotoxicity and its molecular mechanism of the typical environmental pollutant , acrolein through the studying on DNA damage effects induced by acrolein .

选用Wistar大鼠和昆明系小鼠对马波沙星的遗传毒性进行研究。

Wistar rat and closed Kunming strain mice were selected to study the genetic toxicity of marbofloxacin .

ICH遗传毒性研究指导原则修订的最新进展

ICH Guideline on Genotoxicity : Latest Progress in Revision

应用SOS显色试验研究消毒剂的遗传毒性

Study of the genotoxicity of disinfectants with the SOS chromotest

SOS显色法测定水体中遗传毒性

SOS Color Development Method for Determining Genetic Toxicity Substances in Water Sample

遗传毒性试验，包括Ames试验和小鼠骨髓嗜多染红细胞微核试验。

Heredity toxicity test , including Ames test and mouse micronucleus test .

用Ames试验检测水源水和自来水中的遗传毒性

Determination of Genetic Toxicity of Source Water and Drinking Water by AMES Test

结论HQ可致HLF细胞DNA和细胞核损伤，产生遗传毒性作用。

Conclusions Exposure to HQ could cause DNA and nucleus damage inducing genotoxic effects on HLF .

目的研究甲醛对中国仓鼠肺细胞（CHL细胞）DNA和RNA的损伤作用，探讨甲醛遗传毒性的分子机制。

Objective To study the damage of DNA and RNA in CHL Chinese hamster cells induced by formaldehyde and explore its genotoxic mechanism .

目的探索应用彗星实验（单细胞凝胶电泳技术，SCGE）测定鲤鱼红细胞DNA损伤以评价地面水污染遗传毒性效应的可行性。

Objective To explore the feasibility of assessing the genotoxic effect for surface-water pollution using carp erythrocytes with comet test .

从染色体、生殖细胞和DNA的角度对其遗传毒性进行研究，利用骨髓微核试验和鼠伤寒沙门氏菌回变试验对其致突变性进行研究。

Study genetoxic of the secondary metabolites of Rhizoctonia Leguminicola from three angles : chromosome , cell granule and DNA . Research its mutagenicity through bone marrow micronucleus test and Ames test .

GMA对雄性小鼠生殖细胞也有遗传毒性。

GMA was also genotoxic to germ cells of male mice in vivo .

结论氯化消毒饮用水浓集物对N2具有DNA损伤作用，具有遗传毒性。

Conclusion The organic concentrate of drinking water can cause the DNA damage of ras gene and it is considered as a kind of genotoxic substance .

目的了解甲氨蝶呤（MTX）的作用机制，探测其作用的遗传毒性靶器官。

Objective To explore the mechanism of methatrexate ( MTX ) further and the genotoxic target organs .

T-2毒素遗传毒性作用的初步研究

The genotoxic effects of T-2 toxin , a trichothecene produced by Fusarium fungi

同时，采用人外周血淋巴细胞彗星试验，对各水样有机浓集物的生物毒性进行了研究，结果表明水样浓集物可对淋巴细胞DNA产生不同程度的损伤，存在一定的遗传毒性。

In addition , the Comet assay was employed , and results showed DNA damages in human lymphocytes were induced after exposure to organic extracts from water samples and the potential genetic hazardousness existed .