甾体药物

甾体药物生产过程中，微生物转化反应占有不可取代的地位，其中重要的反应有羟基化反应和C1,2位脱氢反应。

Microbial conversion is playing an irreplaceable role in the synthesis of steroid medicines , among which hydroxylation and C1,2 dehydrogenation are the most important reactions .

甾体药物安宫黄体酮中杂质的分离和鉴定

Isolation and identification of impurity in steroid drug Megestrol acetate

我国利用剑麻皂素合成甾体药物的研究进展

Development of Synthesis of Steroid Drugs from Tigogenin in China

妇女计划生育甾体药物的研究与开发

Research and development of steroidal drugs used in family planning for women

远位功能化及其在甾体药物合成中的应用

Remote functionalization and its application in synthesis of steroid drugs

几种甾体药物及其生物转化中间产物的高效液相色谱分析

The high-performance liquid chromatography of the steroid medicine and their bio-transformation intermediates

甾体药物生产废水的生物处理

Biological Treatment of the Wastewater from Steroid Drug Production

甾体药物化学的新进展&甾体受体的研究近况

Recent Advances in Medicinal Chemistry of Steroid & The Survey of Researches in the Steroid Receptors

药品行政保护品种介绍：甾体药物（三）（续二）

Product brief of administrative protection of pharmaceuticals : steroidal agents ( 3 ) ( continuation 2 );

甾体药物作为仅次于抗生素第二大类药物，在日常生活中具有很广泛的应用。

Steroidal drugs is the second largest category drugs after antibiotic , it has extensive applications in our life .

本研究的目的是研究烟曲霉酸合成基因簇中后修饰基因的功能及其在甾体药物制备中的价值。

This study aims to identify the functions of post-modification genes of helvolic acid gene cluster and investigate their value in steroid drugs industry . 1 .

甾体药物的发现及成功合成是近半个世纪来医药工业取得最引人注目的两大进展之一，成为仅次于抗生素的第二大类药物。

During the past 50 years , the discovery and synthesis of steroid drugs is one of the two remarkable developments in medical industry , which has become the second large drug inferior to antibiotics .

金龟子绿僵菌中烟曲霉酸合成基因簇的克隆和基因功能分析金龟子绿僵菌是甾体药物羟化反应的常用菌，具有较高的烟曲霉酸生产水平。

Cloning of helvolic acid gene cluster of M. anisopliae and analysis of its gene functions . M. anisopliae , commonly used strain in the hydroxylation reaction of steroid drugs , has a high level of helvolic acid production .

非甾体抗炎药物与ACE抑制剂的相互作用

Drug Interaction between Nonsteroid Anti-inflammatory Drugs and Angiotensin Converting Enzyme Inhibitors

目的探讨非甾体类药物（NSAID）致消化道溃疡病及急性胃肠粘膜病变的内镜特点及影响因素。

Objective To present the endoscopic character of the gastrointestinal ulcer and acute mucosal disease by NSAID and their affection .

指出了COX2是非甾体抗炎药物治疗作用的靶酶。

It was indicated that COX 2 was the target enzyme of inflammation .

盾叶薯蓣（DioscoreazingiberensisC.H.Wright）是我国特有的、具有重要经济意义的药用植物，其有效成分薯蓣皂甙元（diosgenin）是合成甾体激素药物的重要原料。

Dioscorea zingiberensis C. H. Wright of dioscoreaceae is an important medicinal plant growing only in China by reason that diosgenin in its rhizome is a widely used starting material for hormone drugs .

目的建立一种非水毛细管电泳法（NACE）分离非甾体抗炎药物，并对奥沙普秦肠溶片进行定量分析。

OBJECTIVE To establish a method of nonaqueous capillary electrophoresis ( NACE ) to separate non-steroidal anti-inflammatory drugs ( NSAIDs ) and determine the content of oxaprozin in enteric-coated tablet .

甾体激素药物生产中，甾体母核的多个基团需要进行修饰，甾体微生物C11α-羟基化反应是重要的甾体转化反应之一。

In the production of steroid hormone drug , some groups of steroid need modifying , C_ ( 11 )α - hydroxylation is one of the most important ones .

Dio是合成各种甾体类药物的前体化合物，作为一种类固醇，其对免疫功能具有广泛的作用，具有促进TNF-α分泌，抑制IgE产生，上调调节性T细胞等作用。

Dio is a precursor compound to synthesize various steroidal drugs . As a steroid , it has a wide range of effects on immune function , such as inducing the TNF-a secretion , suppressing IgE production , and up-regulating T regulatory cell production .

本论文用生物转化和化学合成方法对C19甾体类药物中间体及其衍生物和异斯特维醇羟基衍生物的合成进行了研究。

In this paper , the studies on the microbial transformation and chemical synthesis of the intermediates of steroid drugs and isosteviols have been carried out with biological and chemical methods .

非水毛细管电泳法分离分析非甾体抗炎药物

Separation and analysis of non-steroidal anti-inflammatory drugs by nonaqueous capillary electrophoresis

环氧化酶及非甾体抗炎药物的研究进展

Progress in research on cyclooxygenase and non-steroidal anti-inflammatory drugs

武汉地区21家医院2000～2002年非甾体抗炎药物市场分析

Analysis of NSAIDs Used in 21 Hospitals of Wuhan Area During 2000 ~ 2002

微生物转化在当前甾体激素药物的生产中具有重要应用意义。

Microbial transformation of steroid hormones has important significance of application in the current production of drugs .

非甾体类药物致消化道溃疡病及急性胃肠粘膜病变60例内镜特征分析

Analysis endoscopic expression of 60 cases of gastrointestinal ulcer and acute mucosal disease by nonsteroidal anti-inflammatory drugs

治疗组用特效风湿酒治疗，对照组用雷公藤加非甾体类药物治疗。

The treatment group was treaded by Special Effective Wine for Rheumatism , the control group by Thunder God Vine plus non-steroid medicine .

目的：黄姜中提取的薯蓣皂甙元是合成甾体激素药物、抗炎药物和甾体避孕药物的主要原料。

Objective : The diosgenin extracted from yam can be synthesized the steroid hormone medicine , the anti-inflammatory medicine and the steroid contraceptive .

甾体类药物具有重要的生理活性，在临床上有广泛的应用，是仅次于抗生素的第二大类药物。

Due to the significant physiological activity , steroid drugs have been widely used in clinic application as its second place following antibiotic drugs .

其根茎中含有的薯蓣皂甙元是合成甾体类药物的重要前体，具有极高的药用经济价值。

The rhizome of it contains much diosgenin which is an important precursor for synthetic production of steroid drugs , and it has high economic value .