氯硝柳胺

另外，参考《中华人民共和国药典》（2005版）和《英国药典》（2003），对氯硝柳胺分析方法进行了改进，制订了HPLC分析方法。

With referrence of Chinese pharmacopoeia and British pharmacopoeia , the HPLC analysis method of niclosamide has been made .

在适当溶剂中将氯硝柳胺与乙醇胺反应，制得氯硝柳胺乙醇胺盐，经元素分析、IR和NMR鉴定了结构。对该化合物的熔点测定进行了讨论。

Ethanolamide salt of niclosamide was prepared by reaction niclosamide with ethanol amide and identified by elemental analysis , IR and1HNMR.Its melting point was discussed .

Top-down方法制备氯硝柳胺纳米剂的研究

Preparation of niclosamide nanoparticle by the method of Top - down

最后采用氯硝柳胺粗品与有机胺成盐继酸性水解精制产品，通过HPLC内标法测定其纯度达99%以上，符合医药级标准，回收率高达≥97%，产品质量稳定。

Finally , good results were obtained with above 99 % product purity by HPLC and more than 97 % recovery through purification of the crude with some organic amines . grade .

并将氯硝柳胺与EcM2、氯硝柳胺可湿性粉剂与EcM2按不同比例混合，在25±1℃恒温条件下浸泡钉螺48h和72h，观察钉螺死亡情况。

The snails were immersed at the condition of constant temperature 25 ? 1 ℃ for 48 hours and 72 hours and then to observe the death of snails .

24h抑制钉螺上爬半数有效浓度（EC50）为5.86mg/L。现场喷洒试验：密达利2g/m2喷洒后7d钉螺死亡率大于90%，灭螺效果和氯硝柳胺1g/m2相当（P>0.05）。

When sprayed with active ingredient 2 g / m2 of META-Li in the field , the snail death rate was above 90 % after 7 days , similar to that of niclosamide .

氯硝柳胺乙醇胺盐喷粉法现场灭螺效果与费用研究

Cost-effective analysis of eliminating oncomelania with 4 % niclosamide ethanolamine salt

氯硝柳胺现场检测方法和检测仪的研究与开发

Development of method and detector for niclosamide detection in field

50%氯硝柳胺乙醇胺盐可湿性粉剂的高效液相色谱测定

Determination of Niclosamide Ethanolamine Salt 50 % WP by HPLC

黄素腺嘌呤二核苷酸二钠盐和氯硝柳胺的合成与分析

Synthesis and Analysis of Both Flavine Ademine Dinucleotide and Niclosamide

强化微电解法预处理氯硝柳胺生产废水的研究

Research on pretreatment of niclosamide wastewater by improved micro-electrolysis

目的研究氯硝柳胺在现场水体及土壤中对螺作用的持效期。

Objective To study the effective duration of niclosamide in water and soil .

氯硝柳胺悬浮剂对钉螺影响的酶组织化学观察

Enzyme-histochemical observation on influence of suspension concentrate of niclosamide in Oncomelania hupensis snails

4%氯硝柳胺乙醇胺盐粉剂现场杀灭钉螺效果观察

Snail Control Effect of 4 % Powder of Niclosamide Ethanolamine Salt in Field Trial

目的实验室条件下，采用萃取光度法测定水中氯硝柳胺含量。

Objective To study the method and conditions of determination of niclosamide in water .

本文对氯硝柳胺的提纯分离方法进行了研究。

In this article , separation and purification methods of niclosamide have been studied .

结论萃取光度法能用于水样中氯硝柳胺含量的现场检测。

Conclusion Extraction photometry is suitable for determination of niclosamide in water in the field .

环保型氯硝柳胺缓释球杀灭血吸虫尾蚴现场研究

Killing effect of slow release niclosamide ball on cercariae of Schistosome japonicum in the field

氯硝柳胺缓释球研制与杀血吸虫尾蚴的效果观察

Development of slow - release niclosamide ball and studies on its effect of killing cercaria

目的制备氯硝柳胺乙醇胺盐纳米剂并观察其杀螺效果。

Objective To prepare a novel nano-suspension of niclosamide ethanolamine and evaluate its molluscicidal effect .

氯硝柳胺控释扩散剂的研制及杀灭血吸虫尾蚴效果

Preparation of controlled-diffuse concentrate of niclosamide and its effect on killing cercariae of Schistosoma japonicum

氯硝柳胺生产废水处理工程实践

Engineering Practice on Niclosamide Wastewater Treatment

氯硝柳胺乙醇胺盐的合成

Synthesis of Ethanolamide Salt of Niclosamide

聚乙二醇基氯硝柳胺衍生物体外抑制钉螺乙酰胆碱酯酶活性的研究

Inhibitory effects of niclosamide derivatives containing polyethylene glycol groups on acetylcholinesterase activity of Oncomelania snail in vitro

萃取光度法测定水中氯硝柳胺含量的研究结果在实验室条件下，氯硝柳胺的提取率达93%。

Determination of niclosamide in water with extraction photometry Results The recovery of niclosamide was 93 % .

复方增效氯硝柳胺悬浮剂的研究Ⅰ复方悬浮剂的研制及特性分析

Development of a novel synergism compound suspension concentrate Of niclosamide and chlorphoxim I . Formula and its characteristics

氯硝柳胺的熔点在233℃。熔点：151～155℃；

The melt point of niclosamide is 233C . the melting range : between 151C and 155 C .

目的评价4%氯硝柳胺乙醇胺盐粉剂现场灭螺效果。

Objective To evaluate the snail control effect of4 % powder of niclosamide ethanolamine salt in the field .

氯硝柳胺脂肪胺盐和水杨酰胺化合物的合成及其杀螺、抗血吸虫活性

Studies on the synthesis of salicylamides and alkamine salts of niclosamide and their activities against Schistosoma japonicum and Oncomelania

通过对匀质压力及循环次数的控制，可以制得符合粒径要求的氯硝柳胺纳米悬浮液。

By controlling homogenization pressure and cycle number , niclosamide nano suspension meeting the size requirement could be prepared .