染料木

结论：染料木黄酮促进体外培养的乳鼠颅盖骨成骨细胞DNA和胶原的合成，促进增殖和分化。

Conclution : Genistein increased osteoblast DNA and collagen synthesis in neonatal rat calvaria cultures , and promoted osteoblast proliferation and differentiation .

染料木黄酮对MCF-7细胞肿瘤相关基因表达的影响

Effects of genistein on tumor-associated gene expression in MCF-7 cells

染料木黄酮在Beagle犬体内代谢动力学的剂量依赖性研究

Dose-dependent pharmacokinetic study of genistein in Beagle dogs

目的研究染料木黄酮（Genistein，GST）对人子宫内膜癌细胞株HEC-1B的作用。

Objective To investigate the effect in human endometrial carcinoma cell line HEC-1B induced by Genistein .

研究了用高效液相色谱法测定大豆制品中2种异黄酮成分染料木黄酮Genistein和大豆黄素Daidzein含量的色谱条件。

Two isoflavones in soybean product , genistein and daidzein , were determined by High performance liquid chromatography ( HPLC ) .

pKa值7.9942。结论：染料木黄酮为弱酸性脂溶性药物。

The pKa value of genistein was 7.9942 . CONCLUSIONS Genistein is a kind of subacid and fatsoluble drug .

染料木黄酮抑制子宫内膜癌细胞HEC-1B增殖作用的研究

Antiproliferative Effect of Genistein on Human Endometrial Carcinoma Cells HEC-1B in Vitro

目的：研究染料木黄酮（Gen）对T细胞体外活化及增殖的影响，并探讨其机制。

AIM : To study the effect of genistein on activation and proliferation of T cells , and explore the molecular mechanism of genistein .

此外，染料木黄酮可明显降低MDA-MB-435细胞对人工重组基膜的黏附能力，其效应呈剂量依赖性。

Meanwhile , genistein also reduced the adhesion of MDA-MB-435 cells to Matrigel .

大豆异黄酮（soybeanisoflavones）是大豆中重要的非营养成分，它主要包括以糖苷结合形式存在的染料木黄酮苷（genistin）和黄豆苷（daidzin）。

Soybean isoflavones are the important non-nutritious ingredients in soybeans . They mainly contains of genistin and daidzin , which exist in glucoside-combined forms .

目的研究染料木黄酮（Genistein，Gen）对137Csγ射线照射提高小鼠的免疫功能。

Objective To study the effect of genistein on immune functions of ~ ( 137 ) Cs γ - ray irradiated mice .

目的探讨染料木黄酮（Genistein）和正钒酸钠（SodiumOrthovanadate，Na3Vo4）对椎间盘软骨终板软骨细胞的作用。

Objective To study the effects of Genistein and Sodium orthovanadate ( Na3Vo4 ) on the chondrocyte in the endplate of intervertebral discs .

实验测定了染料木黄酮在不同溶剂中的溶解度、不同pH值下的油/水分配系数（HBL）和pKa值。

Determine the physical and chemical constans of genistein The solubility in different solvents , the oil / water detached coefficient and pKa value of genistein were determined by UV spectrophotometry .

目的：体外研究染料木黄酮（genistein）对人乳腺癌细胞（MDA-MB-435）肌动蛋白细胞骨架及黏附能力的影响。

Objective : To investigate the effects of genistein on the the actin cytoskeleton and the adhesion of human breast cancer cells ( MDA-MB-435 cells ) .

目的：测定染料木黄酮在不同溶剂中的溶解度、油/水分配系数、pKa值。

OBJECTIVE The solubility in different solvents , the oil / water detached coefficient and pKa value of genistein were determined for the study of its absorption in vivo .

目的：观察染料木黄酮（genistein）对前列腺癌细胞PC-3生物学行为的影响，探讨genistein预防前列腺癌的可能性。

AIM : To investigate the effect of genistein on the biological behavior of PC 3 cell line of carcinoma of prostate and explore the possibility of genistein used as a preventive drug .

研究了D160大孔吸附树脂对染料木黄酮的吸附性能。

The sorption behavior of macroporous adsorption resin ( D160 ) for genistein was studied .

染料木黄酮（genistein）是一种具有生物活性的植物雌激素，以异黄酮苷的形式广泛存在于豆科植物之中，尤其富含于黄豆（0.2～1.5mg·g~（-1））及其制品中。

Genistein , a principal soy isoflavone and a kind of plant estrogen with bioactivity , exists in leguminosae plant in the form of genistin , especially in soy and its products .

结论染料木黄酮能下调MCF-7/HER-2细胞HER-2/neu受体的PTK活性和蛋白磷酸化水平，抑制uPA表达，这可能是染料木黄酮抗乳腺癌血管生成的分子机制之一。

Conclusion Genistein could down-regulate the activity of PTK and the protein phosphorylation of HER-2 / neu receptor , and inhibit the expression of uPA in breast cancer cells , which is possible one of the molecular mechanisms of genistein anti-angiogenesis in breast cancer .

许多类黄酮都具有抗肿瘤活性，如槲皮素、染料木黄酮、黄芩素、Flavopiridol等，且它们对正常细胞没有或很少有毒性。

Flavonoids , such as quercetin , genistein , baicalein and Flavopiridol have antitumor activity , in which only a few compounds present cytotoxic properties in cells that do not proliferate .

大豆中的异黄酮主要有两种形式：染料木黄酮和黄豆苷原。

Main isoflavones derived from soybean were genistein and daidzein .

不同剂量染料木黄酮及其代谢产物在大鼠胆汁中的排泄动力学

Biliary excretion of genistein and its metabolite at different doses in rats

染料木黄酮对骨形成的促进作用研究

Study on the promotive effect of genistein on bone formation

染料木黄酮对γ射线损伤小鼠免疫功能的影响

Effect of genistein on immune function of γ - ray irradiated mice

染料木黄酮对生长板软骨细胞胶原合成的影响及其机制

The effect and mechanism of genistein on collagen synthesis of growth plate chondrocytes

染料木黄酮在大鼠肝微粒体代谢的酶动力学

Enzyme kinetics of genistein metabolism in rat liver microsomes

染料木黄酮对慢性缺氧大鼠血管活性物质的调节作用

The Regulative Effects of Genistein on Vascular Active Factors in Chronic Hypoxic Rats

结论染料木黄酮有促进骨形成，减少切除卵巢后骨量丢失的作用。

Conclusions Genistein reduces bone loss in ovariectomized rats .

染料木黄酮抑制小鼠变应性接触性皮炎的实验研究

Inhibitory effects of genistein on mouse allergic contact dermatitis

染料木黄酮不是通过雌激素受体促进成骨细胞增殖

Genistein plays a role in the proliferation of osteoblast not through estrogen receptor